GREAT NEWS: They found a perfect bone marrow donor for my Dad!!

[jus_the_facts]

....got the news monday mornin' before we buried my mammaw...they found a 100% match from a stranger no less AND two backups that're only a point from bein' perfect. The only bad thing is now his insurance co. wants to weigh in and nitpick as to whether or not they wanna pay for it...BUT this is the BEST NEWS we've had in over two years since he was diagnosed with Leukemia. :bounce:

And another tid bit of potential good news for me personally...I proposed an idea to my Dad's *son he never had* who's quite wealthy and has an investment business and he is interested in possibly investing in my idea and maybe I'll get to be a big part in makin' it happen....a few weeks ago a business man in my town bought the empty super K-mart building here and wants to sell spaces for like a mini mall...so my idea was to rent the center section of it and open an ice skating rink as we've never had one in my town...the city had a minor league hockey team and had the equipment to turn our civic center into an ice rink at one time...but it went belly up...they would let people skate on the rink when the team was outta town...so I thought it'd be a good idea to give the kids something new to do around here and center a rink inside this building and have shops around it to give parents something to do while their kids skate....he's supposed to call me so we can discuss this further...I hate to get my hopes up but hell if I could just drive the Zamboni I'd be happy to have a damn JOB at least...sigh. *fingers crossed* :)

[Nicholas D Wolfwood]

1. That's fantastic news!!!

Congrats!!!!

[jus_the_facts]

4. Thanks!

:hi:

[Zing Zing Zingbah]

2. That's awesome! n/t

[jus_the_facts]

5. yeah 'tis!

:hi:

[Lone_Wolf_Moderate]

3. Praise God. That's really great news.

[jus_the_facts]

8. AMEN!

:hi:

[commander bunnypants]

6. good news

congrats

CB

[jus_the_facts]

9. Thanks!

:hi:

[GreenPartyVoter]

7. Excellent! *hugs*

[jus_the_facts]

10. VERY! {{{hugsback}}}

:hi:

[MissMillie]

11. That's terrific!

I'm very happy that you found several good matches.

I'm sure he'll be on the road to recovery in no time.!

[jus_the_facts]

12. I'm so relieved...his last doctor said he wasn't a candidate...

....they moved back here and I talked to his new doctor and asked just WHY he wasn't a candidate and he got the ball rollin' on a transplant as soon as my dad went back into remission this last time...after I told him *I* wanted everything that could be done to be done...sigh..but he listened and hopefully this will be exactly what he needs to be cured. :hi:

[uppityperson]

13. Congratulations and good job for not giving up for your Dad

And thanks for the good news of today.

[jus_the_facts]

14. Thanks.....

...and you're welcome as well!! :hi:

[arcane1]

15. sweet!!

:bounce:

[jus_the_facts]

17. yep...best news in a looong time.....

:hi:

...gotta take my kitties in for surgery tomorrow mornin'! x(

[arcane1]

20. ah

that always sucks :(

[jus_the_facts]

22. yeah I'm dreadin' it for 'em too....poor babies...

.....gonna be beside m'self for the next couple days...s'gonna be really quiet and lonely here without 'em. :cry:

[maveric]

16. Maybe there is a God? Thats great news!

[jus_the_facts]

18. Yeah...go figure eh.....

:hi:

[Beetwasher]

19. I'm So Happy For You!!!

You really needed that good news darlin'!!! That's terrific!

[jus_the_facts]

21. Indeed....for once there was good news that followed the bad....

...and I'm SOOOO thankful for it too....Thanks sweetie!! :hi:

[bigwillq]

23. Great news!

:bounce:


Wish your dad the best for me!

Hope you're hanging in there!:hi: :hug:

[jus_the_facts]

25. I will and I am.....

...thank you!! :hi: :hug:

[da_chimperor]

24. Wonderful news!

I hope that his insurance company goes along with everything. I'm crossing my fingers for you and your dad. :hi:

[jus_the_facts]

26. Thanks.....

....they just HAVE TO dammit!!! :hi:

[joeybee12]

27. Great news! Don't know much about bone marrow transplants, but

I sort of recall matching people up is extremely difficult. Your father is very lucky!

[jus_the_facts]

28. a perfect match from a stranger is literally 1 in 1 million....

...yes indeed he certainly has been extremely fortunate!! :hi:

[joeybee12]

32. Wow! Then I guess saying he's "lucky" is quite an understatement!

:hi:

[egoprofit]

29. congrats!!!!

[jus_the_facts]

34. Thanks!!

:smoke:

:hi:

[southpaw]

30. Exxxxxxxccccelllent!!!!

Good luck with the financial plan, too!

:hi:

[jus_the_facts]

35. Thanks sweetie.....

:hi: :hug:

[CatBoreal]

31. Doing the Snoopy Dance of Joy for you and your Dad!

That's terrific news!

[jus_the_facts]

36. LOL....thank you!!

:hi:

[DU GrovelBot]

33. ## PLEASE DONATE TO DEMOCRATIC UNDERGROUND! ##

==================
GROVELBOT.EXE v3.0
==================



This week is our first quarter 2005 fund drive. Democratic
Underground is a completely independent website. We depend almost entirely
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your support.

[blondeatlast]

39. YOU GOT A LOTTA DAMN NERVE, GB!

Don't you beg in JTF's good news!

Perhaps GB wants us to donate in Dad jus_the_facts' name?

[jus_the_facts]

42. Awwwww.....let him grovel......

...he doesn't know any better!! :D Thanks again dear!! :hug:

[blondeatlast]

37. How wonderful!

Just fantastic news. Sending blessings to Dad jus_the_facts and to you.

Keep us posted.

Here's a little analgesic: :hug:

[jus_the_facts]

38. Thank you so much....{{{{hugsback}}}}

:hi:

[GumboYaYa]

40. I bet an ice skating rink would kick ass in Monroe.

That's a good idea. Good luck.

Also, great news on your Dad.

[jus_the_facts]

41. Hey stranger....I thought so too....

....sure hope he'll give it a lot more thought...I learned to ice skate when we lived in Shreveport for 2 years when I was in kindergarden and 1st grade....before I ever learned to roller skate...never got to again after movin' here and always missed it!!

How've you been? :hi:

[GumboYaYa]

43. I'm doing well.

I haven''t talked to you in ages. I'm so glad to hear so much positive news.

With all the minor league hockey in LA now, I'm sure there is a market for an ice-skating rink.

[jus_the_facts]

44. Glad to hear you're well....

:hug:

....sure hope it pans out...the kids need something new to do around here...and I definitely need something to do too...quick..fast...and in a hurry lol! :D

[nothingshocksmeanymore]

45. Kudos on both accounts!

Here's hoping the cells work for your dad and here's to your entrepreneurial streak :toast:

[jus_the_facts]

46. Thank you.....

....you know I've been beside m'self about the flip/flop that other doctor did about the transplant...sooo glad he finally got another doctor..and the man actually listened to me!! :toast:

Sure would be nice to have a cool job drivin' a zamboni...guess I could attempt to re-learn to skate too lol!! :hi: :loveya:

[nothingshocksmeanymore]

50. I WANNA DRIVE THE ZAMBONI!!!!

:D

[jus_the_facts]

56. Okay....I'll let you fill in for me.....

....if/when it happens....you gotta PROMISE you and yours will come visit me and my establishment!!! :D

[nothingshocksmeanymore]

59. Are you kidding me????

YOu live in one of my favorite states on the planet! We'll get down there.

[matcom]

47. WOOOOOOHOOOOOO

congrats :toast:

to your dad too! keep us posted!

[jus_the_facts]

51. Thanks babe....

....will do!! :beer: :hi:

[Padraig18]

48. Awesome!

Great news!

:thumbsup::bounce::party::toast::beer:

[jus_the_facts]

52. Yes indeed!!

:hi: :hug:

[guitar man]

49. That's great!!

good to hear!!! :bounce:

[jus_the_facts]

53. Yesssss....oooo I LOVE your sig pic....the MULE RULES!!!!!

:loveya:

:hi:

[guitar man]

57. I can't get enough

One of the last real rock bands out there. :bounce:

[jus_the_facts]

66. I can't either..and I totally agree.....

...ZombyWoof sent me a bunch o'stuff I'd never heard...s'all I wanna listen to now!! :headbang:

[guitar man]

69. me too

I just finished recording an album for a local band. We wound up with 9 great original tunes and one intoxicating cover of the Mule's "Soulshine". Can't wait to release it. :bounce:

[jus_the_facts]

71. Oh MAAAAN....that's my most favorite song by 'em too.....

...I LOVE LOVE LOVE that song!!! :loveya:

[guitar man]

72. We cut a hell of a version of it

It is the song on the disc where we called in a few friends from the local music scene to make some guest appearances, including Rocky Frisco from JJ Cale's band on piano.

[jus_the_facts]

73. I'd love to hear it....

:headbang:

[guitar man]

74. I should have

..an mp3 I can post soon. We just sent the disc off to Nashville for mastering, it should be back by next week.

[jus_the_facts]

75. Don't let me miss it.......

...pm me the link if/when you do post it! Thanks in advance! :bounce:

[guitar man]

77. I sure will!

[Skittles]

54. OUTSTANDING

man, I've been on that blood registry list for years and have never been called - I just think it would be so cool to be called! :D

[jus_the_facts]

58. I know it me too...sure hope I'll be able to do the same for someone.....

....one day as well!! :hi: :hug:

[Book Lover]

55. Oh good

Thanks for sharing the good news.

[jus_the_facts]

60. S'been what I've waited to hear for a couple years now....

....my Dad told me right before we buried his Momma on Valentines day...my heart went from crushed to filled lemme tell ya! :hi:

[Misunderestimator]

61. Yay! That's wonderful news!!!

Keeping good thoughts for you... :hug:

[jus_the_facts]

63. Thank you so very much.....

:hug:

....ya'll will have to come visit me so Teena can guest drive the zamboni!! :D

[Misunderestimator]

68. You Know it! You'll be one of the first we visit!

:hug:

[jus_the_facts]

70. Coolness....

:bounce:

[LeftPeopleFinishFirst]

62. yayyyyy

Glad things are looking up for you! :hug:

[jus_the_facts]

65. Thanks Maggie....

....hope all's well with you these days...sure did need some good news for a change!! :hi: :hug:

[Richard Steele]

64. Warm fuzzies fer everyone! Nice to hear some good news here~!

[jus_the_facts]

67. INDEED!!!

..so GLAD I could oblige! :bounce:

[shesemsmom]

76. I'm sorry about your mammaw

but thrilled for you day. Hold those insurance people's feet to the fire make them do right by your POP. And good luck on your business venture!!!!

[jus_the_facts]

78. Thank you....

...very much....will definitely be interesting to see what these insurance people tell us..and it BETTER be good news too....and thanks again about the venture...that'd be just too awesome to be involved in...to be able to give back to my community would be a dream come true. :hi:

[shesemsmom]

79. Keep us posted on both!!!

[HysteryDiagnosis]

80. You need to read and great news about the donor... please do a little

reading here, it cannot hurt, and it may help you to understand what you are up against and what you may be able to do to help him be stronger in his fight. Best wishes, 4Mor

http://www.lef.org/protocols/prtcl-067.shtml#leukemia

[jus_the_facts]

81. Thank you for the link.....

....he's been sick for over 2 years now and dreads all that the transplant entails...especially since his last chemo and recent remission...but eventhough it's going to be extremely difficult to endure and an even longer stint in the hospital with a transplant..he's still willing to fight hard to try and stay around for awhile longer for my mom and the rest of our family....just hopin' the insurance will cover it...thanks!! :hi:

[HysteryDiagnosis]

82. Well... you see.... much of the damage done by almost all diseases is done

by oxidative stress... now before I get labeled an antioxidant freak.. just look at these papers from the NIH that explains how certain "special" antioxidants help protect against disease... I believe Alpha Lipoic Acid was listed on the link I put up as an adjunct therapy... here is why.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11841833
1: Mol Immunol. 2002 Feb;38(10):733-45. Related Articles,
Differential effects of the antioxidant alpha-lipoic acid on the proliferation of mitogen-stimulated peripheral blood lymphocytes and leukaemic T cells.

Pack RA, Hardy K, Madigan MC, Hunt NH.

Department of Pathology, University of Sydney, NSW 2006, Sydney, Australia.

The effects of the antioxidant alpha-lipoic acid (LA) on the proliferation of mitogen-stimulated human peripheral blood lymphocytes (HPBL) were investigated in comparison to its effects on the proliferation of two leukaemic T cell lines, Jurkat and CCRF-CEM. At low mM concentrations, LA inhibited in a dose-dependent manner DNA synthesis of HPBL stimulated with either phorbol myristate acetate (PMA) in combination with ionomycin (IoM), or phytohaemagglutinin (PHA). At similar concentrations, LA inhibited the proliferation of Jurkat and CCRF-CEM cells. However, LA was preferentially cytotoxic to the leukaemic cell lines. The selective toxicity of LA to Jurkat cells was shown by electron microscopy (EM) to be due to the induction of apoptosis. Furthermore, LA had different effects on the secretion of interleukin-2 (IL-2) and steady-state levels of IL-2 mRNA in mitogen-stimulated HPBL depending on the mitogens used. LA dramatically increased the induction of IL-2 mRNA and IL-2 protein secretion in PMA/IoM-stimulated HPBL, whereas it inhibited these in HPBL stimulated with PHA. The differential effects of LA on normal and leukaemic T lymphocytes may indicate a new route towards development of therapeutic agents.

PMID: 11841833

1: Leukemia. 1997 Sep;11(9):1546-53. Related Articles, Links

Induction of the differentiation of HL-60 promyelocytic leukemia cells by vitamin E and other antioxidants in combination with low levels of vitamin D3: possible relationship to NF-kappaB.

Sokoloski JA, Hodnick WF, Mayne ST, Cinquina C, Kim CS, Sartorelli AC.

Department of Pharmacology, Cancer Center, Yale University School of Medicine, New Haven, CT 06520, USA.

Epidemiological studies have provided evidence that diets rich in antioxidant nutrients may reduce the risk of cancer. To evaluate the possibility that dietary phytochemicals with antioxidant potential would create an environment capable of affecting the differentiation of HL-60 leukemia cells, we measured the effects of vitamin E and other dietary antioxidants on the differentiation produced by low levels of vitamin D3 and analogs thereof. Vitamin E succinate and other antioxidant compounds (ie butylated hydroxyanisole, beta-carotene and lipoic acid) used alone had no significant effect on the differentiation of HL-60 cells; however, these agents markedly increased the differentiation produced by vitamin D3. Previous studies from this laboratory have shown that a sequence-specific antisense phosphorothioate oligonucleotide to the Rel A subunit of NF-kappaB enhanced the differentiation of HL-60 cells produced by several inducing agents. Consistent with these observations, vitamin E succinate caused a marked reduction in the nuclear content of NF-kappaB both in the presence and absence of vitamin D3. These findings suggest that NF-kappaB may be a factor in regulating the differentiation of myeloid leukemia cells. The results also indicate that combinations of vitamin D3 and analogs thereof with dietary antioxidants may be useful in overcoming the differentiation block present in acute promyelocytic leukemia cells.

PMID: 9305611

[jus_the_facts]

83. Much appreciated....

....will pass this along as well! :)

[HysteryDiagnosis]

84. Well.... I hate to do this.... but.... I am forced to.

http://www.google.com/search?hl=en&q=glyconutrients+leukemia&btnG=Google+Search

[jus_the_facts]

85. Again...I will definitely pass this information along....

....very interesting that it's not more well known since it seems as if it's quite beneficial...but that is how our healthcare system works these days...if it's not pharmacutical then it's unknown and not to be trusted..eventhough we are seeing how untrustworthy they're becoming every day now...thanks again for giving me this information. :hi:

[HysteryDiagnosis]

86. No problem... funny thing is, these saccharides, are naturally

ocurring in your body. You create them from glucose and perhaps sucrose everyday all day. It is a rather large metabolic strain to produce them, and then if you are stressed, bacterially/virally challenged, genetically "imperfect", etc, it can be an impossibility to produce them in sufficient quantities to have good and proper cell to cell communication. I hope you will find your way to understanding their importance IN VIRTUALLY ALL DISEASE PROCESSES.

Scientific/Medical info at www.glycoscience.com

[salin]

87. Great news about your father...

going to have faith that the insurance co will come around.

love the personal news as well - very cool! :loveya:

[jus_the_facts]

92. Thanks salin.....

:hi: :loveya:

[GOPisEvil]

88. Woohoo!!!

Good news all around! Best wishes to you and your dad! :party:

[jus_the_facts]

93. Thanks David...

:hi:

[Michigander4Dean]

89. SWEET!

Best of luck to you!

[jus_the_facts]

95. Thank you...

:hi:

[Pale Blue Dot]

90. WOO HOO!

Keeping you and your dad in my thoughts. :loveya:

[jus_the_facts]

96. Thanks sweetie...

:hi: :loveya:

[Lisa]

91. I've been in the Unrelated Bone Marrow donor registry for years ...

A couple of people I know have gotten "the call", and judging by how they felt, you can bet that the excitement is just as high on that end!

Good luck to your dad -- but with the improvement in techniques and anti-rejection drugs, the odds sound pretty good even if you have to go with one of the kinda-close matches (4 or 5 out of 6 factors?).

[jus_the_facts]

97. Thanks...

....yeah he's so very fortunate....sure hope I'll be able to pass it forward to someone one day as well!! :hi:

[roguevalley]

94. honey, what great news. I am so happy for you. :-D

[jus_the_facts]

98. Thank you...

:hi: