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kpete

(71,984 posts)
Thu Sep 20, 2012, 10:01 PM Sep 2012

Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers

Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers

A pair of scientists at California Pacific Medical Center in San Francisco has found that a compound derived from marijuana could stop metastasis in many kinds of aggressive cancer, potentially altering the fatality of the disease forever.

"It took us about 20 years of research to figure this out, but we are very excited," said Pierre Desprez, one of the scientists behind the discovery, to The Huffington Post. "We want to get started with trials as soon as possible."

..........................

Desprez, a molecular biologist, spent decades studying ID-1, the gene that causes cancer to spread. Meanwhile, fellow researcher Sean McAllister was studying the effects of Cannabidiol, or CBD, a non-toxic, non-psychoactive chemical compound found in the cannabis plant. Finally, the pair collaborated, combining CBD and cells containing high levels of ID-1 in a petri dish.

"What we found was that his Cannabidiol could essentially 'turn off' the ID-1," Desprez told HuffPost. The cells stopped spreading and returned to normal.

more:
http://www.huffingtonpost.com/2012/09/19/marijuana-and-cancer_n_1898208.html
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Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers (Original Post) kpete Sep 2012 OP
Huge news, especially with the courts Bennyboy Sep 2012 #1
does this mean i'll live forever? spanone Sep 2012 #2
This is only ''news'' for those who haven't been paying attention. DeSwiss Sep 2012 #3
Good research -- thanks for posting it. nt. Mr_Jefferson_24 Sep 2012 #8
De nada. DeSwiss Sep 2012 #9
Oh, look. Science! Le Taz Hot Sep 2012 #12
You're welcome, and remember: DeSwiss Sep 2012 #13
Cannabis side-effects: Happiness, Stress Relief, Stops the Spread of Cancer, and Jail. tridim Sep 2012 #4
K&R Mnemosyne Sep 2012 #5
Good news fadedrose Sep 2012 #6
This explains in part why it's illegal. Mr_Jefferson_24 Sep 2012 #7
I hope so, kpete. Jack Sprat Sep 2012 #10
But, but, but. . .it's a gateway drug. It will lead to more, harder drugs, and the DEA has it Suji to Seoul Sep 2012 #11
In fact tama Sep 2012 #18
Gateway to twinkies and obesity. Suji to Seoul Sep 2012 #19
Not in my experience tama Sep 2012 #20
leave to someone in the medical field to ruin an attempt at levity. Suji to Seoul Sep 2012 #21
Joking is fine tama Sep 2012 #22
Can they derive some form of it that doesn't make you get high? MadrasT Sep 2012 #14
My sister in law used it during her cancer treatments. Cerridwen Sep 2012 #15
High CBD strains won't get you very high.. tridim Sep 2012 #17
this discovery is not new and these results will be buried as well piratefish08 Sep 2012 #16
Critical to the Colorado measure musiclawyer Sep 2012 #23
 

Bennyboy

(10,440 posts)
1. Huge news, especially with the courts
Thu Sep 20, 2012, 10:23 PM
Sep 2012

taking up the rescheduling of cannabis soon.

For the first time since 1994, the question of medical marijuana will go before a federal court. The United States Court of Appeals for the D.C. Circuit has agreed to hear a lawsuit challenging the DEA’s classification of marijuana as a dangerous drug with no medical value. The ten-year-old suit, brought by Americans for Safe Access, will present scientific evidence on marijuana’s therapeutic properties.
The appeal brief calls the DEA’s refusal to analyze numerous studies on the drug’s medical uses “arbitrary and capricious,” and asks the court to order the DEA to conduct a hearing on the scientific evidence.
Marijuana is currently a Schedule 1 substance with “high potential for abuse,” in the same legal classification as heroin and morphine. In spite of numerous petitions to reschedule the drug, the federal government has maintained that marijuana has no medical value and launched costly and aggressive eradication efforts. Just a few weeks ago, the Justice Department sued to close the largest medical marijuana dispensary in the country, even as Congress, in a rare bipartisan move, prepared a bill to protect medical marijuana possession.
But the conditions for the ASA’s case — in which oral arguments will be presented on the morning of October 16 — are optimal.

READ MORE AT LINK: http://thinkprogress.org/justice/2012/08/01/620211/federal-court-will-review-marijuanas-classification-as-a-dangerous-drug-with-no-health-benefits/

 

DeSwiss

(27,137 posts)
3. This is only ''news'' for those who haven't been paying attention.
Thu Sep 20, 2012, 10:30 PM
Sep 2012
- And that would include most people and certainly the leaders of this country. Here is a collection of links to scholarly articles and medical articles that I started back in 2006. I have no idea if the links still works. I gave up trying explain this to people who didn't give a shit. Particularly after our current leadership started arresting sick people and taking away their only cure:

The below research links are to articles, scientific studies and abstracts which report that the tetrahydrocannabinol and cannabinoids in marijuana can halt the spread the MRSA bacteria and numerous other types of cancer cells -- including:

MRSA: http://www.webmd.com/news/20080904/marijuana-chemicals-may-fight-mrsa

Prostate Cancer: http://www.goldjournal.net/article/S0090-4295%2805%2901160-X/abstract

Breast Cancer: http://mct.aacrjournals.org/cgi/content/abstract/6/11/2921

Lung Cancer: http://www.nature.com/onc/journal/v27/n3/abs/1210641a.html

Pancreatic Cancer: http://cancerres.aacrjournals.org/cgi/content/abstract/66/13/6748

Brain Cancer: http://www.ncbi.nlm.nih.gov/pubmed/16804518

And in addition to the cancer research, here's a report from an Austrailian newspaper about a French study that found that cannabidiol in marijuana may prevent the development of prion diseases such as BSE because it inhibits the accumulation of prion proteins in infected mice and sheep. Bovine Spongiform Encephalopathy (AKA: Mad Cow Disease: http://www.420magazine.com/forums/medical-marijuana-facts-information/82605-cannabidiol-may-effective-preventing-mad-cow-disease.html





===================
new ones:

http://www.medicalnewstoday.com/articles/120477.php

http://healthcare.zdnet.com/?p=1324

http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Marijuana-Active-Ingredient-Stimulates-Cancer-Cell/ArticleNewsFeed/Article/detail/591443?contextCategoryId=40139

Pharmacology: Marijuana and your heart
Michael D. Roth1 - Abstract
Marijuana smoke can have harmful effects on the heart. But one of its active components may ease inflammation and slow the progression of coronary artery disease.
http://www.nature.com/nature/journal/v434/n7034/full/434708a.html

JunD is involved in the antiproliferative effect of Delta9-tetrahydrocannabinol on human breast cancer cells
http://www.nature.com/onc/journal/v27/n37/abs/onc2008145a.html

A pilot clinical study of Delta9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme
http://www.nature.com/onc/journal/v27/n37/abs/onc2008145a.html

Pot of gold for glioma therapy
Daniele Piomelli

Department of Pharmacology, 360 Med Surge II, University of California, Irvine, California 92697-4625, USA
piomelli@uci.edu
Cannabinoid agonists arrest tumor progression in a rodent model of malignant glioma. Will these molecules provide a starting point for new strategies for anti-cancer therapy (313-319)?
http://www.nature.com/nm/journal/v6/n3/abs/nm0300_255.html

======================================================================

calamus
n. type of plant

Easton's Bible Dictionary

Calamus
the Latin for cane, Hebrew Kaneh, mentioned (Ex. 30:23) as one of the ingredients in the holy anointing oil, one of the sweet scents (Cant. 4:14), and among the articles sold in the markets of Tyre (Ezek. 27:19). The word designates an Oriental plant called the "sweet flag," the Acorus calamus of Linnaeus. It is elsewhere called "sweet cane" (Isa. 43:24; Jer. 6:20). It has an aromatic smell, and when its knotted stalk is cut and dried and reduced to powder, it forms an ingredient in the most precious perfumes. It was not a native of Palestine, but was imported from Arabia Felix or from India. It was probably that which is now known in India by the name of "lemon grass" or "ginger grass," the Andropogon schoenanthus. (See CANE.)

http://www.scribd.com/doc/2466222/Marijuana-The-Bible

======================================================================

by Terry Winger

Was there marijuana in the anointing oil as described in exodus 30:23?

The original Hebrew for calamus, is Kaneh-bosem or Qaneh (Kaw-naw) Bosem. Some translations have this as “fragrant cane” or “aromatic cane.” Some researchers have argued that this is actually Sweet Cane or Sugar Cane, although the term sweet does not occur in the original manuscripts.

Kaneh-Bos sounds remarkably close to the modern day word Cannabis. Could it be that cannabis was the plant given by God to be used in the Holy Anointing Oil?


Cannabis has certainly been cultivated since the beginning of recorded history. Its uses for rope, sails and rigging into ancient times are well documented.

Imagine the amount of cannabis rope it would have taken to construct the Temple of Solomon. What other way was there to construct ropes at that time, which could lift the weights of not only the Temple of Solomon, but in fact, the Pyramids themselves.

Cannabis was thought to be an Indo-European word specifically of Scythian Origin. The Scythians were largely responsible for the spread of cannabis into Europe. The Scythe, was an invention of the Scythians, used for the harvest of cannabis. This has come to us in the legends of the “Grim Reaper”

Herodotus, an early Greek ethnographer, in the 5th Century BC wrote of the Scythians and their use of cannabis.

The Scythians as they were known by the Greeks, were known, by the Semites as the Ashkenaz. Among the earliest references to Ashkenaz people is found in Genesis 10:3 where Ashkenaz was listed as the son of Gomer, the great Grandson of Noah. The Sythians lived around and traded with the Semites at least as early as 600 BC.

Zoroaster the prophet of the Ancient Magi, whose kings followed the Star of Bethlehem based on the ancient prophesies, used a drink called Haoma which has been documented to contain cannabis.

As early as 1925 experts have argued that, both the Assyrians and the Babylonians, used Cannabis in their temple incense, Circa 500 BC.

In 1993, the Albany New York Times Union reported, that the first physical evidence that Marijuana was used as a medicine in the ancient Mideast, was found. The Israeli scientists found residue of marijuana along with the skeleton of a girl who had died 1600 years before.

In this press release, researchers from the Hebrew University, stated that references to marijuana as a medicine are seen as far back as 1,600 BC in Egyptian, Assyrian, Greek, and Roman Writings.

If you actually buy the Calamus translation for the Holy Oil, then you assume that God specified in Exodus 30:23 a drug commonly known as Ecstasy. Calamus contains an ingredient called aserone. This is a hallucinogen which is metabolized in the liver as trimethoxyamphetamine or ecstasy. The Middle Eastern version of this plant is far more toxic than it`s North American Cousin. This is deadly to flies and other insects.The Exodus 30:23 reference refers to sweet Calamus. If you look at this in the Strong’s concordance where they spell this as qaneh rather than kaneh, they pronounce this as Kaw-Naw, a reed, calamus, and cane are listed as possible translations. The term sweet used in Exodus 30:23 in Hebrew is Bosem. According to the Webster's New World Hebrew Dictionary, Bosem is perfume; scent. The Concordance: the Hebrew is Bosem #1314, fragrance, by impl. spicery; also the balsam plant:----smell, spice, sweet (odour). In some Bibles sweet calamus is translated as aromatic or fragrant Cane. It is where the bosem is fused to the word kaneh or qaneh that the cannabis translation becomes apparent. So then to pronounce this we have kaw-naw-bosem, and is spelled in English qaneh-bosem or kaneh-bosem.

In 1936, Sara Benetowa, later Known as Sula Benet, an etymologist from the Institute of Anthropological Sciences, in Warsaw wrote a treatise, "Tracing One Word Through Different Languages." This was a study on the word Cannabis, based on a study of the oldest Hebrew texts. Although the word cannabis was thought to be of Scythian origin, Benet's research showed it had an earlier root in the Semitic Languages such as Hebrew. Benet demonstrated that the ancient Hebrew word for Cannabis is Kaneh -Bosem. She also did another study called Early Diffusion and Folk Uses of Hemp. There is a reprint of this in Cannabis and Culture ISBN : 90-279-7669-4. On page 44, she states, "The sacred character of hemp in biblical times is evident from Exodus 30:23, where Moses was instructed by God to anoint the meeting tent and all of its furnishings with specially prepared oil, containing hemp." On page 41 Sula Benet writes: In the course of time, the two words kaneh and bosem were fused into one , kanabos or kannabus know to us from the Mishna. According to the Webster's New World Hebrew Dictionary, page 607 the Hebrew for hemp is kanabos.

Sara Benetowa discovered that the Kaneh-Bosm or Cannabis is mentioned 5 times in the Old Testament. The first occurrence appears in the Holy Anointing Oil as Calamus, (Exodus 30:23). Sara argued that the translation of Calamus was a mistranslation which occurred in the oldest Bible the “Septuagint” and the mistranslation was copied in later versions.

Cheers
Terry Winger
Producer of "The Fire Baptism and the Lost Sacraments"

http://www.book-of-thoth.com/article1718.html

===================
Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition

Maria M Caffarel email, Clara Andradas email, Emilia Mira email, Eduardo Perez-Gomez email, Camilla Cerutti email, Gema Moreno-Bueno email, Juana M Flores email, Isabel Garcia-Real email, Jose Palacios email, Santos Manes email, Manuel Guzman email and Cristina Sanchez email

Molecular Cancer 2010, 9:196doi:10.1186/1476-4598-9-196
Published: 22 July 2010

http://www.molecular-cancer.com/content/9/1/196

=========================

Cannabidiol
What is Cannabidiol?

Cannabidiol, also known as CBD, is a cannabinoid found in Cannabis. It is a major constituent of the plant, representing up to 40% in its extracts.

CBD alone is not intoxicating, but displayed sedative effects in animal tests. It may decrease the rate of THC clearance from the body, perhaps by interfering with the metabolism of THC in the liver. CBD does not appear to affect either the CB1 or CB2 receptors. Some research, however, indicates that CBD can increase alertness.

Medically, it appears to relieve convulsion, inflammation, anxiety, and nausea, and to inhibit cancer cell growth. Recent studies have shown cannabidiol to be as effective as atypical antipsychotics in treating schizophrenia. In November 2007 it was reported that CBD reduces growth of aggressive human breast cancer cells in vitro and reduces their invasiveness. It thus represents the first non-toxic exogenous agent that can lead to down-regulation of tumor aggressiveness. It is also a neuroprotectiveantioxidant.

(Wikipedia)

http://www.showmethefacts.org/medical-marijuana-facts/cannabidiol/

==================================

Added: August 30, 2010

Marijuana effective in reducing pain, study shows
http://www.theglobeandmail.com/life/health/marijuana-effective-in-reducing-pain-study-shows/article1689573/

=================================
Added 6-22-2011

Marijuana and Diabetes
Submitted by ccason Mon 06/13/2011

Diabetics are always looking for the next big treatment option for controlling their disease. One such topic that is continuing to draw attention is using marijuana to curb the effects of the disease. But does it work?

In some parts of the country, marijuana is being used as a treatment for diabetes. This is due to media exposure concerning some interesting benefits that can be derived from it's use. Among those symptoms, the two main ones are increased blood flow and helping to control glucose levels.

http://www.battlediabetes.com/articles/diabetes/marijuana-and-diabetes

 

DeSwiss

(27,137 posts)
9. De nada.
Fri Sep 21, 2012, 02:45 AM
Sep 2012



[font color=green]''Hey, I don't like arresting little old ladies with
cancer anymore than the next guy, but what can
I do? This is a war!''[/font]


Le Taz Hot

(22,271 posts)
12. Oh, look. Science!
Fri Sep 21, 2012, 03:10 AM
Sep 2012

What a concept! Thank you so much for posting. I'm bookmarking this page for future reference. There is SO much mythology surrounding cannabis, wouldn't it be nice if we were to actually rely on FACT as opposed to hysteria ala Reefer Madness?

I was reading some of the responses in that thread and it's amazing that such misinformation and ignorance is still so rampant.

 

DeSwiss

(27,137 posts)
13. You're welcome, and remember:
Fri Sep 21, 2012, 03:20 AM
Sep 2012
- Whether you call it Kaneh-bosem or Qaneh (Kaw-naw) Bosem or even if you just call it ''weed'' -- it's approved by all the top Potentates, Religious and Spiritual Leaders, Disciples and Messiahs from time immemorial!

[center][/center]

tridim

(45,358 posts)
4. Cannabis side-effects: Happiness, Stress Relief, Stops the Spread of Cancer, and Jail.
Thu Sep 20, 2012, 10:41 PM
Sep 2012

I'll grow the high CBD strains. It's covered. We don't need it in $80/pill form.

Mr_Jefferson_24

(8,559 posts)
7. This explains in part why it's illegal.
Thu Sep 20, 2012, 11:48 PM
Sep 2012

Imagine how unhapppy Big Pharma would become if people were permitted to cultivate non-toxic, non-addictive, stress relieving, cancer inhibiting plants in their own back yard.


 

Jack Sprat

(2,500 posts)
10. I hope so, kpete.
Fri Sep 21, 2012, 03:00 AM
Sep 2012

But like another similar posting, you are bound to get some claiming this is nothing new or extraordinary at all. Like I said though, I sure do hope so.

 

Suji to Seoul

(2,035 posts)
11. But, but, but. . .it's a gateway drug. It will lead to more, harder drugs, and the DEA has it
Fri Sep 21, 2012, 03:03 AM
Sep 2012

classified as a Cat-1 drug, so there is no legitimate medicinal purpose or use for Marijuana.

 

tama

(9,137 posts)
20. Not in my experience
Sat Sep 22, 2012, 08:36 AM
Sep 2012

Munchies do happen, but the overall/holistic effect of pot over metabolism seems to be rather against than for obesity. Also severe cases of cannabis related psychosis can be a very effective anti-obesity treatment.

 

tama

(9,137 posts)
22. Joking is fine
Sat Sep 22, 2012, 10:39 AM
Sep 2012

and appreciated. I've heard that the medical field of Ayahuasca curanderos hold yearly event of getting together, drinking huge amounts of extremely concentrated and potent jungle juice and competing who can longest keep on sitting straight and joking before going BWUYAAAAARRRGGGGHHHH!!! We joke about and together with these kinds spirit guides and healers because because they are worth respect and serious attitude.

MadrasT

(7,237 posts)
14. Can they derive some form of it that doesn't make you get high?
Fri Sep 21, 2012, 07:08 AM
Sep 2012

Or have they already?

Pot makes me sick and paranoid. I hate it. I would have a big problem if it were a cure or even an effective treatment for a disease I had -- I can't use it in its natural form.

It is exciting news anyway, my issue aside, 'cause it isn't all about me.

Cerridwen

(13,257 posts)
15. My sister in law used it during her cancer treatments.
Fri Sep 21, 2012, 07:18 AM
Sep 2012

She, too, used to get sick and paranoid when she smoked pot and had stopped smoking it many years ago. When going through surgery, chemo, and radiation treatment, she smoked pot to help with the side effects of her treatment and experienced no sickness and paranoia and it helped her to eat and avoid the pain and nausea from the cancer treatment.

Pot, in her case at least, worked on the treatment side effects rather than making her high when she used it. After she was finished with her treatments, smoking pot, again caused her illness and paranoia. It appeared to effect her differently depending on whether or not she was ill to begin with.

I hope that made sense; my coffee's not quite kicked in yet.

tridim

(45,358 posts)
17. High CBD strains won't get you very high..
Fri Sep 21, 2012, 08:03 AM
Sep 2012

Lots of amazing people are developing high CBD strains right now for medical uses.

You likely got sick and paranoid because you were doing something illegal, not because of the effects of the cannabis. I have some friends that claimed the same side effects and I asked them, "Are you afraid of getting caught?" and they all say yes. The thought of jail can cause a pretty intense stress reaction.

musiclawyer

(2,335 posts)
23. Critical to the Colorado measure
Sat Sep 22, 2012, 11:42 AM
Sep 2012

I think it will pass. Does POTUS and Holder want to die in this hill ? This almost assures they will if they try to challenge thè people's will

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