If Pence gets sick& can't take over if need be, Nancy has to resign speaker to take over POTUS.

one position at a time.

She would only be assuming its powers as an acting president.

https://constitutioncenter.org/interactive-constitution/amendment/amendment-xxv

President Pelosi has a GREAT ring to it

It would be ironic if Amy Coney Barrett sunk her own nomination on a microscopic scale.

Pence would become president. There's roughly four weeks between now and the election, so the likelihood of him getting sick (or worse dying) is very low. If it should, then yes, Nancy would have to resign as Speaker of the House to become the president, something which I suspect she would have no problem with - she is old enough that it would be a nice retirement present. If Biden wins, it's almost certain that she would work closely with Biden during the transition, and maybe even give a nice jumpstart to what would likely be a very tumultuous transition otherwise.

Additionally, is it necessary for an acting president (as opposed to a president who succeeded to the actual office) to resign from Congress?

If the president can't fulfill the duties, pence is president. If he can't fulfill the duties, Nancy is president. Lines of succession. There is not an acting President in the constitution.

It's in the 25th amendment.



It is only when the president dies or is removed from office that that the Vice President becomes President.


https://constitutioncenter.org/interactive-constitution/amendment/amendment-xxv
https://www.law.cornell.edu/constitution/amendmentxxv

I only just read the actual amendment myself today.

I was wondering why neither Bush nor Cheney had to resign the vice presidency when they temporarily took over for an incapacitated president.

Pence is likely to have only mild symptoms even if he were to get covid.

not clear what the question or concern is

will be very interesting to see how it all plays out.

The Speaker would be assuming the powers and the duties of the presidency, not the office itself.

She'll have much more power than she has now. Moscow Mitch would be totally impotent.

Nancy could step down temporally---the House appoints Biden Speaker---he assumes the Presidency-appoints Harris as VP--Nancy gets reelected to Speaker ---EZPZ-------and this is what might happen ---if the GOP Senate is sick ----maybe AOC could be appointed to SCOTUS

The Constitution does not require the speaker to be an incumbent member of the House of Representatives, although every speaker thus far has been.[4] The speaker is second in the United States presidential line of succession, after the vice president and ahead of the president pro tempore of the Senate.[2]