Nearly One-Third of Covid Patients in Study Had Altered Mental State

[octoberlib]

Nearly a third of hospitalized Covid-19 patients experienced some type of altered mental function — ranging from confusion to delirium to unresponsiveness — in the largest study to date of neurological symptoms among coronavirus patients in an American hospital system.

And patients with altered mental function had significantly worse medical outcomes, according to the study, published on Monday in Annals of Clinical and Translational Neurology. The study looked at the records of the first 509 coronavirus patients hospitalized, from March 5 to April 6, at 10 hospitals in the Northwestern Medicine health system in the Chicago area.These patients stayed three times as long in the hospital as patients without altered mental function.

After they were discharged, only 32 percent of the patients with altered mental function were able to handle routine daily activities like cooking and paying bills, said Dr. Igor Koralnik, the senior author of the study and chief of neuro-infectious disease and global neurology at Northwestern Medicine. In contrast, 89 percent of patients without altered mental function were able to manage such activities without assistance.

Patients with altered mental function — the medical term is encephalopathy — were also nearly seven times as likely to die as those who did not have that type of problem.

https://www.nytimes.com/2020/10/05/health/Covid-patients-mental-state.html?smtyp=cur&smid=tw-nytimesscience

[erronis]

1. Covid brain

https://www.emptywheel.net/2020/10/04/october-covid-surprise-so-much-bullshit-so-little-time/

Given how little stable genius he had to start with...

Trump’s little joy ride this evening did himself no favors. His body’s under huge stress and he doesn’t appear to recognize this, even if the Regeneron multi-antibody therapy is working.

There’s a dearth of news about that antibody cocktail’s success under compassionate use with other COVID patients. Regeneron released information about a study in which 275 out of a total 1100 participants received this therapy.

What’s weird about the antibody cocktail is that they didn’t release a study with data but a goddamned press release on Tuesday September 29, at 4:01 p.m.

Conveniently one minute after market close but before the debate, and potentially after some persons in the White House knew they were COVID-positive.

The steroid Trump received — dexamethasone — was the next appropriate step in the protocol for COVID based on Trump’s depleted oxygen levels, which means the antibody cocktail wasn’t working as quickly or as well as needed.

Dexamethasone would have been dispensed because Trump’s oxygen level fell substantially; when asked, Conley said his level had not fallen into the low 80s — a level which would be cyanotic. This means Trump’s O2 probably did fall to 85% and likely needed oxygen and the steroid to prevent cyanosis.

...

But Trump is NOT receiving respiratory support consistently based on yesterday’s photos and proof-of-life video, this evening’s his stunt ride as well as the sketchy information his physicians have given. The steroid would not be as beneficial to him as it would be to patients on ventilators.

To my knowledge Trump’s physicians have already shot their COVID arsenal. If Trump has additional difficulty breathing he’ll likely be put under anesthesia into an induced coma and intubated. If he gets to that point he won’t have a choice about it because his low oxygen level could cause a cascade of organ failures — a crash.

We can deduce his lungs are compromised because of Dr. Conley’s hedging about their appearance (“There’s some expected findings, but nothing of any major clinical concern,” he said).

It’s likely Trump’s being monitored for cardiac symptoms given the use of ultrasound and the frequency with which COVID causes myocarditis. We can’t rule out the possibility Trump had cardiac symptoms when he went on an unscheduled visit to Walter Reed last November which may mean he’s at greater risk of myocarditis.

And it’s likely Trump’s got some degree of COVID brain as well, which the steroid will make worse — he’ll have cloudy thinking but with mania. A number of doctors from different fields have expressed concerns about dexamethasone’s affect on Trump’s capacity given the possibility of mania, delirium/confusion while under its influence.

We don’t even know yet if Trump has been free of fever without antipyretic medication.

I’m not a doctor, but none of this suggests to me that Trump will be ready to be released from Walter Reed tomorrow, joy ride or not.

[octoberlib]

4. Informative post . Thanks!

[The Velveteen Ocelot]

2. But with Trump it's impossible to tell.

[BigmanPigman]

3. How are we supposed to be able to tell with the fucking moron?

He is normally crazy. Covid can make you crazy while ill. The massive amounts or steroids he's on makes you crazy. He could have Crazy × 3.

Chris Cuomo had a guest and doctor on a month ago and both the guest and Chis have lingering health issues after recovering from Covid. Depression and mental issues is a common lingering problem.

[underpants]

5. One person I knew thought her granddaughter was a nurse who visited

her in the hospital

[tinrobot]

6. He already has an altered mental state.

I guess this is the point where he gets even worse.