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question everything

(47,465 posts)
Mon Sep 5, 2016, 12:57 PM Sep 2016

For some drug firms, highs and lows of value pricing are evident

Consumers who are outraged by huge increases in the price of the lifesaving EpiPen allergy drug could also direct a little of their anger toward what’s happened with another old-fashioned drug, called H.P. Acthar Gel.

Hardly cutting-edge science, it’s derived from the pituitary glands of pigs and was actually developed by the Armour & Co. meatpacking company, and has long been used to treat infantile spasms. And like the EpiPen, whose maker has come under harsh criticism lately, it’s a shockingly expensive drug that once used to be very cheap.

Not that long ago the drug sold for maybe $50 per vial, giving it so little commercial value that a drug company called Questcor in 2001 acquired rights to it for $100,000. Questcor jacked up the price and turned itself into a hot enough specialty pharmaceutical company to be bought by Mallinckrodt PLC. H.P. Acthar Gel now costs about $35,000 per vial (with a coupon!) and Mallinckrodt’s pricing practices have been pounded by health care systems, insurers and a bearish investment pro.

(snip)

What pharmaceutical companies do is called value pricing, setting the price based upon the product’s perceived value to the customers who will buy it. Cost is irrelevant. What’s important to grasp as well is that it’s the same pricing process pretty much every savvy business manager has adopted. Anti-inflammatory medication, tacos from a food truck, a replacement battery for the car or estate planning advice from a lawyer, it doesn’t matter, the prices for all were arrived at pretty much the same way. It’s hard to think of a product with a price set only on what it costs to make it.

(snip)

Congressional hearings don’t usually get called to look into the pricing of a drug if the price inches up over a long period, even though by 2016 the price may be eye-popping. A great example is a drug developed by Novartis called Gleevec. This drug was a genuine breakthrough medication for patients with a chronic form of leukemia when it came out in 2001. Novartis developed it for what the company thought of as a relatively small market.

Initially Novartis priced it to cost about $26,000 for a year of treatment. Novartis admitted at the time that getting acceptance for a drug so expensive could be an uphill battle. Well, the customers did buy it, enough for the company to steadily increase its price. It’s now more than $145,000 for a year’s treatment, making this one-time niche drug the biggest seller for a multibillion-dollar global company. Gleevec sales last year were nearly $4.7 billion.

There are something like 18 generic versions of the drug now available around the world including a few in Canada. North of the border the generic medication is sold for about $8,800 a year, according to an analysis published in May in the cancer treatment journal the ASCO Post. A year’s supply costs only about $400 in India. A generic version of the same medication finally came to the market here, too, after a delay when Novartis essentially paid a generic maker to hold off bringing it out. It was priced about $140,000 per year.

So what’s the value-based pricing argument here? Can drugmakers really claim that this miracle drug has a genuine value here, with our richly funded health care system, that’s 350 times the perceived value to buyers in India? It’s doubtful too many Americans relying on this drug will buy that argument. They may yet take to Facebook in droves to share their disgust.

http://www.startribune.com/lee-schafer-for-some-drug-firms-highs-and-lows-of-value-pricing-are-evident/392181281/

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For some drug firms, highs and lows of value pricing are evident (Original Post) question everything Sep 2016 OP
self kick (nt) question everything Sep 2016 #1
Interesting Egnever Sep 2016 #2
 

Egnever

(21,506 posts)
2. Interesting
Tue Sep 6, 2016, 04:10 AM
Sep 2016

As someone who is on not gleevec but a similar TKI called dasatinib I am horrified at the cost.

My pills are 10k per month, completely out of affordability range. I am fortunate in that I have insurance and the manufacturer provides a copay coupon. The end result is my insurance pays 7.5k and the coupon covers the other 2.5k a month.

I see this as a complete scam of my insurance which wouldn't bother me much except my insurance is a co-op. So my pills are putting a fat dent in the co-ops ability to stay solvent something they are struggling with. Thinking about it it would still bother me if it was normal insurance.

The Dasatinib is for the same thing the gleevec is for but has a much higher success rate. I am fairly certain that there is not a generic for dasatinib yet which makes this story even more tragic as there are a lot of people that gleevec is not effective for that dasatinib would be. Also the side effects of dasatinib are generally lower than with gleevec. That means to me that there are a lot of people out there suffering needlessly until this drug is available in a generic form.

There has to be a better way to do this.

I will say that despite all of the above the drug is an amazing accomplishment. Until gleevec CML was a death sentance within 3-5 years now with gleevec and the newer even better TKI drugs you are more likely to die of something else.

Hard to put a price you are willing to pay on that.

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