Moderna's coronavirus vaccine found to be nearly 95 percent effective in a preliminary analysis
Source: Washington Post
Biotechnology firm Moderna announced Monday that a preliminary analysis shows its experimental coronavirus vaccine is nearly 95 percent effective at preventing illness, including severe cases a striking initial result that leaves the United States with the prospect that two coronavirus vaccines could be available on a limited basis by the end of the year.
The news comes a week after pharmaceutical giant Pfizer and its German partner BioNTech lifted the stock market and peoples hopes with the news that their coronavirus vaccine was more than 90 percent effective.
Its extremely good news. If you look at the data, the numbers speak for themselves, said Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases, who was one of three people briefed on the data by an independent committee Sunday morning. I describe myself as a realist, but Im fundamentally a cautious optimist. I felt wed likely get something less than this.
I said certainly a 90-plus-percent effective vaccine is possible, but I wasnt counting on it.
Modernas vaccine, co-developed with Faucis institute, is being tested in 30,000 people. Half received two doses of the vaccine, and half received a placebo. To test how well the vaccine works, physicians closely monitored cases of covid-19 to see whether they predominantly occurred in people who received the placebo group.
Read more: https://www.washingtonpost.com/health/2020/11/16/covid-moderna-vaccine/
Link to tweet
underpants
(182,279 posts)mpcamb
(2,855 posts)per Washington Post:
https://www.washingtonpost.com/health/2020/11/16/covid-moderna-vaccine/
Also, no dilution required at the point of care, unlike the Pfizer vaccine.
Some big advantages.
Johnson and Johnson may soon have a single dose vaccine, too.
underpants
(182,279 posts)People lose track of things like that. I know I forgot my second shingles shot.
Regular freezer level is a really big deal.
https://www.democraticunderground.com/100214562663
KewlKat
(5,624 posts)BumRushDaShow
(127,312 posts)I can't believe the fact that the U.S. registered 1,000,000 positives in JUST ONE WEEK (this past week) where in the past it initially took months, then a month, then several weeks.
LisaL
(44,962 posts)NT
Iliyah
(25,111 posts)wherein millions will die, but alas, science will prevail, and thank goodness the USA has elected Biden/Harris who gives a damn.
Bengus81
(6,907 posts)Living in Kansas and hunkered down like never before. Covid is raging through this State as Republicans did everything they could to strip Dem Gov Laura Kelly of power to stop or at least slow this shit. A big day in Kansas used to be 250 new cases, now we're hitting 5,000+. Set a new record of 6,051 in one day just a couple of days ago.
Now...the price is being paid big time and I would guess the majority down with this virus are Republicans who wanted their fucking mega churches open, bars open and life as normal back in May. They yelled and screamed about any kind of a mask requirement in business establishments.
These are the same Republican POS that will take a bed away from someone who tried their best to keep from being infected.
BumRushDaShow
(127,312 posts)that here in PA, we have been consistently hitting 5000+ cases a day for almost a week now and we have 4 times the population of Kansas.
And once again I do a -->
Steelrolled
(2,022 posts)with results better than anyone dared to predict. This means the Oxford vaccine and others still coming have a good chance of being effective as well.
The Moderna trial all started with this mother of two, on March 16.
https://www.npr.org/2020/03/21/818759617/i-wanted-to-do-something-says-mother-of-2-who-is-first-to-test-coronavirus-vacci
Yee haw!
icwlmuscyia
(296 posts)"severe cases of prevention" means?
Also, did Moderna purposely expose subjects to the corona virus? I am so curious - article indicates no:
Moderna has committed to completing its trial before applying for emergency-use authorization which means waiting until there are 151 cases of covid-19 in the study. A previous projection showed that the trial might end sometime early next year, but it is instead expected to reach its endpoint in seven to 10 days, Bancel said, because of surging coronavirus cases in the United States. The explosion of virus cases translates into an expedited ability to ascertain whether a vaccine works.
I am skeptical, but hopeful
beachbumbob
(9,263 posts)the need for details is staggering. Were all subjects exposed to COVID?
JustGene
(421 posts)appear to affect the vaccines effectiveness. (No structural change)
Exposure is random (ethics)
Steelrolled
(2,022 posts)Some drug company (not Moderna) said their vaccine was effective with the new mutation (which was not a big surprise, based on what is known about how the vaccine is mutating).
LisaL
(44,962 posts)Because covid is surging, subjects are naturally infected in a community, speeding up the trial.
JustGene
(421 posts)Last edited Mon Nov 16, 2020, 09:33 AM - Edit history (1)
They don't do "direct exposure" without a reliable treatment.
Edit: wrong trial, sorry.
TheRickles
(2,000 posts)WaPo is behind a paywall, unfortunately.
icwlmuscyia
(296 posts)The paragraph I posted said they are nearing 151 (must be some statistically significant number)
TheRickles
(2,000 posts)(thanks for the tip about Covid access being free)
The King of Prussia
(735 posts)Of the total cases (severe & otherwise) 90 were in the placebo group, and 5 were in the vaccine group. Of those 95 cases, 11 were severe and of those 11 severe cases, all 11 were in the placebo group.
[link:https://www.theguardian.com/world/2020/nov/16/moderna-covid-vaccine-candidate-almost-95-effective-trials-show|
TheRickles
(2,000 posts)The King of Prussia
(735 posts)of the 15,000 who were vaccinated, 0 became seriously ill. I'm not sure HOW good that is, but it's put a smile on my face.
TheRickles
(2,000 posts)only 11 got seriously ill. That's a very low morbidity rate, around 0.07%. That seems like very good news, too.
JustGene
(421 posts)I think it would be the same as general stats
Steelrolled
(2,022 posts)This has been widely discussed, but it was not done, not even considered.
I think it should have been seriously considered, and there were no shortage of volunteers. The medical community is very cautious, and I guess the pandemic would have had to be much worse before they would consider.
LisaL
(44,962 posts)Which means many people in control group are quickly getting it, speeding up the trial.
Steelrolled
(2,022 posts)LisaL
(44,962 posts)Of course many would die if that is the case.
Steelrolled
(2,022 posts)I think there might be areas where the large number of infections does start to slow down the spread. Herd immunity is not black-and-white.
not_the_one
(2,227 posts)https://investors.modernatx.com/news-releases/news-release-details/moderna-congratulates-dr-moncef-slaoui-his-appointment-oversee
Strangely, the virus does not require extreme storage and is a few points more effective. What a coincidence.
Sorry, but I will wait for Pfizer, which had NOTHING to do with the turd.
I posted this in the other thread that got locked. It seems no one is making the connection to trump. I will trust no drug company that has anything to do with a vaccine, that has any connection with the turd.
Sherman A1
(38,958 posts)FBaggins
(26,697 posts)It's actually the recent surge in new cases that allowed the trials to see results so quickly... so it's his super-spreader events that made this day possible!
/sarcasm
Kablooie
(18,572 posts)With a lot of side effects and deaths.
Hope these are safer.
Loki Liesmith
(4,602 posts)Dont come close to ours.
Steelrolled
(2,022 posts)but I have seen nothing that suggests deaths or harmful side effects. Is that real news, or just gossip?
yaesu
(8,020 posts)workers seem to dispute the effectiveness claim.
oldsoftie
(12,410 posts)Steelrolled
(2,022 posts)Is there reliable reporting of this?
Ace Rothstein
(3,109 posts)If their vaccine was working then Russia wouldn't be seeing a continuing rise in cases and deaths.
Hortensis
(58,785 posts)A graph in the Moscow Times shows a steep rise from a summer plateau that never dropped.
Ace Rothstein
(3,109 posts)Either nobody in Russia is getting the vaccine or the effectiveness is much closer to 0% than 100%.
Steelrolled
(2,022 posts)Russia, but the US are a number of weeks away (at least) from the vaccine being deployed to the first person (outside the trial). I doubt Russia has any magical ability to instantly manufacture and distribute millions of doses of vaccine, any more than the US does.
Ace Rothstein
(3,109 posts)I think both are expected to have 100 million available in January.
oldsoftie
(12,410 posts)So could be
Steelrolled
(2,022 posts)You need a significant deployment of vaccine before the infections and death rate will be affected. I have not seen any reporting on this, just idle speculation.
LisaL
(44,962 posts)NT
Kablooie
(18,572 posts)Lonestarblue
(9,880 posts)These vaccines have been developed at super speed, and thus neither company has been able to judge possible long-term effects of their vaccines. Once Biden is in office and his team of scientists have reviewed the data, Ill be satisfied. Ill line up for whatever they recommend. Im tired of putting my life on hold.
yaesu
(8,020 posts)review.
Steelrolled
(2,022 posts)A team of independent scientists review the data and report the results.
There continues to be misinformation about how the vaccine development process works. I shouldn't be surprised.
ForgoTheConsequence
(4,846 posts)Facebook and Twitter posts do NOT count. Respectable medical and epidemiological journals only. Thank you.
h2ebits
(632 posts)I have a subscription to the Washington Post but they are offering all coronavirus information for free according to their header. Please click the linked article and check it out. I'd appreciate confirmation from someone who doesn't have a subscription.
Lasher
(27,501 posts)TheRickles
(2,000 posts)Lasher
(27,501 posts)If you are using Chrome as a browser, right click on the link, then select 'open in incognito window'. You're welcome.
iluvtennis
(19,758 posts)forthemiddle
(1,373 posts)After front line workers, and at risk patients I will lining up!
I feel the speed of the vaccine in the best news of this miserable year!
Science Rocks. I cant wait to travel again!
Steelrolled
(2,022 posts)A lot of people don't want to believe good news, maybe because there has been so much bad news this year. The great thing about the vaccine trial results is they come from a panel of independent investigators. And the good thing about the FDA processes is that they have been fine-tuned over many years to reduce conflict of interest.
Aussie105
(5,214 posts)The questions really were:
When?
How long before widespread vaccinations will have the effect of reducing infection and death numbers?
Give it a few years, and you will get a combined flu and COVID shot - updated of course, to cover the latest strains that have shown up.
Then we can all go back to believing the human race is invincible.
In the meantime, while we are waiting, be safe - facemasks, social distancing, avoiding crowds, washing hands.
You know, the basic stuff, that some people seem to have problems with.