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BumRushDaShow

(128,516 posts)
Tue Jun 28, 2022, 07:35 PM Jun 2022

As Monkeypox Spreads, U.S. Plans a Vaccination Campaign

Source: New York Times

Clinics nationwide will begin offering vaccinations against monkeypox to anyone who may have been exposed to the virus, federal health officials announced on Tuesday. Until now, immunizations were offered only to people with a known exposure. States will receive doses of a safer and newer monkeypox vaccine called Jynneos from the federal stockpile, based on the number of cases and the proportion of the state’s population at risk for severe disease, the officials said at a news briefing.

State health authorities may also request supplies of an older vaccine developed for smallpox, which is believed to protect against monkeypox, as well. The Department of Health and Human services will provide 56,000 doses of the Jynneos vaccine immediately and an additional 240,000 doses in the coming weeks. Another 750,000 doses are expected to become available over the summer, and a total of 1.6 million doses by the end of this year. “This vaccine currently has some limitations on supply, and for this reason the administration’s current vaccine strategy prioritizes making it available to those who need it most urgently,” Dr. Rochelle Walensky, director of the Centers for Disease Control and Prevention, said.

The older smallpox vaccine, called ACAM2000, is associated with harsh side effects, including death, in people who are immunocompromised, pregnant women and older adults. The new vaccination plan drew quick criticism from experts, who said the campaign was too small and slow to make an impact. The longer it takes to contain the monkeypox outbreak, the greater the chances that the virus will become entrenched in the United States, particularly among men who have sex with men, researchers warned. “Many of us are concerned that the window is closing for us to be able to eliminate monkeypox,” said Dr. Celine Gounder, an infectious disease expert and editor at large for public health at Kaiser Health News.

“If we don’t start vaccinating more quickly and broadly, we’re going to have a very difficult time containing this,” she said. Ideally, tests and vaccines for monkeypox could have been offered at L.G.B.T.Q. Pride events across the country in order to reach men at high risk of contracting the virus, Dr. Gounder added. Some experts said the plan was also unfair to men at risk who will not have access to the Jynneos vaccine, especially those who have H.I.V. and cannot safely take the older smallpox vaccine.

Read more: https://www.nytimes.com/2022/06/28/health/monkeypox-vaccinations-cdc.html

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As Monkeypox Spreads, U.S. Plans a Vaccination Campaign (Original Post) BumRushDaShow Jun 2022 OP
Ty for sharing! SheltieLover Jun 2022 #1
Oh, yeah, that'll work great. n/t malthaussen Jun 2022 #2
In other Monkeypox-related News.... TheRealNorth Jun 2022 #3
I had... myohmy2 Jun 2022 #4
None of the old smallpox vaccinations are protective anymore BumRushDaShow Jun 2022 #5
There are studies that say you are protected but CDC says opposite womanofthehills Jun 2022 #7
Well I'm not gonna be rushing out for ANOTHER vaccine just yet. oldsoftie Jun 2022 #6

TheRealNorth

(9,471 posts)
3. In other Monkeypox-related News....
Tue Jun 28, 2022, 07:49 PM
Jun 2022
Virus causing monkeypox outbreak has mutated to spread easier


https://www.cidrap.umn.edu/news-perspective/2022/06/virus-causing-monkeypox-outbreak-has-mutated-spread-easier

The strain of the virus in the current monkeypox outbreak in nonendemic countries likely diverged from the monkeypox virus that caused a 2018-19 Nigerian outbreak and has far more mutations than would be expected, several that increase transmission, according to a study today in Nature Medicine.

The study comes from Portugal's National Institute of Health in Lisbon, which was the first institution to genetically sequence the current strain behind more than 3,000 cases of monkeypox in Europe, North America, and other regions that had never seen the virus until this year.

Researchers found the current strain diverges from the original strain by 50 single nucleotide polymorphisms (SNPs), and several mutations made the virus more transmissible. The strain belongs to clade 3 of the West African strain of the virus, which is less fatal than the Congo Basin clade. Monkeypox outbreaks from clade 3 are typically reported from western Cameroon to Sierra Leone and usually carry a less than 1% case-fatality rate.

The authors said the outbreak was likely not caused by undetected silent spread, or from an animal-to-human crossover event. Instead, "Current data points for a scenario of more than one introduction from a single origin, with superspreader event(s) (e.g., saunas used for sexual encounters) and travel abroad likely triggering the rapid worldwide dissemination."

The authors also said the 50 SNPs that diverge from the original strain are far more (roughly sixfold to 12-fold more) than one would expect considering previous estimates of the substitution rate for orthopoxviruses, which typically have 1 to 2 substitutions per site per year.

Modeling study shows potential growth of outbreak
In another study, this one published today in The Lancet Microbe, scientists use modeling to predict what will happen in nonendemic countries if public health measures to curb ongoing outbreaks are not taken.

They predict that, without interventions, the introduction of 3 cases in a country could cause 18 secondary cases, 30 could cause 118 secondary cases, and 300 cases could cause 402 secondary cases.

Contact tracing and surveillance, isolation of symptomatic cases, and ring vaccination would reduce the number of secondary cases by up to 86.1% and the duration of the outbreak by up to 75.7%, the authors conclude.

The authors also said the outbreak is a moderate international concern. Currently, consultants to the World Health Organization are weighing if the outbreak constitutes an international public health emergency during a 2-day meeting.

US, Portugal add more cases
In the United States, the Centers for Disease Control and Prevention said the national total is now 173 in 24 states, an increase of 17 cases since yesterday.

A New York City sexual health clinic offering monkeypox vaccine to men who have sex with men was forced to close because of overwhelming demand. Many men sought the vaccine in the days leading up to Pride celebrations.

Portugal now has 348 monkeypox cases, with 20 new cases in the last 24 hours. Along with Spain and the United Kingdom, Portugal has the most cases in Europe.

In other news, Croatia and Taiwan each reported their first cases of the virus.

myohmy2

(3,142 posts)
4. I had...
Tue Jun 28, 2022, 07:57 PM
Jun 2022

...a smallpox vaccine 65+ years ago, am I still protected?

...actually, I still wear my COVID mask when I'm in public places...(maybe there's about 10% of us who still do)

...remember, we can't force pukes to wear masks or get vaccines like they can force us into unwanted pregnancies...so I hope this monkeypox thing doesn't take off...

...I'm epidemic-ed out...

BumRushDaShow

(128,516 posts)
5. None of the old smallpox vaccinations are protective anymore
Tue Jun 28, 2022, 08:09 PM
Jun 2022

although I do still see mention that it might have left a little bit of antibody memory enough to trigger a tiny bit of a response. Oherwise, in general, I think the thought was that it might be effective for 5 - 10 years if that.

Over the decades, there have been some like miltary, medical personnel, some travelers, etc., who may have received smallpox boosters (and there had been stores of it generated back after 9/11 in case of some kind of bioterrorism).

womanofthehills

(8,661 posts)
7. There are studies that say you are protected but CDC says opposite
Tue Jun 28, 2022, 11:06 PM
Jun 2022

Smallpox Vaccination Effective For Decades, Study Suggests

Summary:
There is concern that bioterrorists might obtain smallpox from a laboratory and release it into the population. However researchers found that lifetime protection is obtained from just one vaccination, even when that vaccination occurred as much as 88 years ago. They conclude that in the event of a smallpox bioterrorist attack, vaccinia smallpox vaccine should be used first on individuals who have not been vaccinated previously.

https://www.sciencedaily.com/releases/2008/11/081130201926.htm

oldsoftie

(12,492 posts)
6. Well I'm not gonna be rushing out for ANOTHER vaccine just yet.
Tue Jun 28, 2022, 08:31 PM
Jun 2022

There ARE downsides to taking vaccine after vaccine. Many RELIABLE specialists have this same opinion. Not "Q" idiots

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