2020 US Senate Election cycle will result in a 50 Democrats and 50 Republicans.
Democrats lose AL(Jones-D) but will pick up CO(Gardner-R),AZ(whoever Ducey-R appoints), NC(Tillis-R) and ME(Collins-R).
CO,AZ,and NC are easy pickups for Democrats.
CO(Gardner-R) won in 2014 by a 2 percent margin against a Udall-D a Democratic incumbent who ran a weak campaign. 2014 was a Republican wave election year. CO is now and will be more Democratic friendly in 2020 than it was in 2014. Democrats won every statewide election in CO in 2018 and in 2016 Democrats won the Presidential and US Senate Race in CO. Democrats have plenty of top tier candidates for CO(Gardner-R). Hickenlooper-D, Perlmutter-D, Cary Kennedy-D, Johnston-D, Joe Salazar-D, Duran-D, Romanoff-D and/or Garnett-D.
AZ(McSally-R) lost in 2018 to Sinema-D by a 2.5 percent margin. The 2018 AZ US Senate Race was an open seat.
NC(Tillis-R) won in 2014 by a 1.5 percent margin against Hagan-D a Democratic incumbent. Whoever is the Democratic nominee against NC(Tillis-R) will benefit from Governor Cooper-D coattails.
Democrats will pick up ME if Collins-R retires or loses in the Republican primary. If Collins-R wins the Republican nomination, she is likely to win by a high single digit margin due to the fact that Collins-R won her US Senate Races in ME in 1996 by a 5.3 percent margin, 2002 by a 16.8 percent margin, 2008 by a 23 percent margin, and 2014 by a 36.8 percent.
The 50th US Senate seat for Democrats is likely to be in GA(Perdue-R loses to Abrams-D or Ossoff-D in 2020).