New test can detect autism in children, scientists say

[nitpicker]

https://www.theguardian.com/society/2018/feb/19/autism-children-blood-urine-test

New test can detect autism in children, scientists say

Blood and urine test, believed to be first of its kind, could lead to earlier diagnosis of autism spectrum disorders

Press Association

Mon 19 Feb 2018 01.05 GMT Last modified on Mon 19 Feb 2018 02.27 GMT

Scientists in Britain say they have developed a blood and urine test that can detect autism in children. Researchers at the University of Warwick said the test, believed to be the first of its kind, could lead to earlier diagnosis of autism spectrum disorders (ASD) in children who could then be given appropriate treatment much earlier in their lives.
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Scientists said their research found a link between ASD and damage to proteins in blood plasma. They found the most reliable of the tests they developed was examining protein in blood plasma, which found children with ASD had higher levels of the oxidation marker dityrosine (DT) and certain sugar-modified compounds called advanced glycation end-products (AGEs).
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The Warwick team worked with collaborators at the University of Bologna in Italy, who recruited 38 children who had been diagnosed with ASD along with a control group of 31 other children between the ages of five and 12. Blood and urine samples were taken from the children for analysis.

The Warwick team discovered there were chemical differences between the two groups. Working with a further collaborator at the University of Birmingham, the changes in multiple compounds were combined using artificial intelligence algorithm techniques to develop a mathematical equation to distinguish between ASD and healthy controls. The outcome was a diagnostic test better than any existing method.

They said the next steps were to repeat the study with further groups of children to confirm the good diagnostic performance and to assess if the test could identify ASD at very early stages, indicate how the ASD is likely to develop further to more severe disease, and assess if treatments were working.
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