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Sat Feb 3, 2018, 02:42 PM

Recent Animal Drug Approvals

I see there is a new flea/tick treatment coming out.

I see the study (32 beagles -- barely enough to make it a "study" ).
Study (singular) Date: March 9, 2015 to September 18, 2015

One dog died, reason unknown (dare I suggest POISONED?).

The other one got sick and was taken out.

Two out of 32 had a bad reaction and/or death.

More about the crap here (see Credelio):

lotilaner
Chewable Tablets
Dogs

>>*Two geriatric dogs developed mildly elevated BUN (34 to 54 mg/dL;
reference range: 6 to 31 mg/dL) during the study

One of these dogs also developed polyuria and a mildly elevated potassium (6.5 mEq/L;
reference range: 3.6 to 5.5 mEq/L) and phosphorous (6.4 mg/dL; reference range: 2.5 to 6.0 mg/dL).

The other dog also developed a mildly elevated creatinine (1.7 to 2.0 mg/dL; reference range: 0.5 to 1.6 mg/dL) and weight loss. One additional dog in the lotilaner group
also developed polyuria.

In addition, one dog experienced intermittent head tremors within 1.5 hours of administration of vaccines, an ear cleaning performed by the owner, and its first dose of lotilaner. The head tremors resolved within 24 hours without treatment. The owner elected to withdraw the dog from the study.

SMART OWNER WHO GIVES A DAMN!


*****

Adverse Reactions:
Although more dogs in the control group had episodes of vomiting and diarrhea than in the treated group, the frequency of vomiting and diarrhea was increased in two dogs in the lotilaner treated group.
One treated dog had four episodes of vomiting 14 to 34 days after treatment. Another treated dog had three episodes of bloody diarrhea 8 to 29 days after treatment and one episode of vomiting 36 days after
treatment. Neither dog required treatment. (uh huh ...)

and ...

In a single arm field study conducted in Australia, one dog with a history of seizures experienced seizure activity, characterized as tremors and glazed eyes, six days after receiving lotilaner. The signs resolved without treatment and the dog completed the 60-day study.

In another single arm field study conducted in Australia, a 10-year-old mixed breed dog died 33 days after receiving lotilaner. The dog was withdrawn from the study 16 days after receiving lotilaner due to pruritus secondary to a suspected harvest mite infestation.

The dog was treated with a topical ectoparasiticide containing pyrethrin, piperonyl butoxide, and N-ocytl bicycloheptene dicarboximide. The dog died seventeen days later. The dog exhibited vomiting, excessive thirst, and lethargy for a couple of days prior to death. The cause of death is unknown.

In three well-controlled field studies conducted in Europe (Germany, Hungary, Portugal, and Spain), seven dogs experienced episodes of vomiting within 2 days after lotilaner administration and two dogs experienced diarrhea within 3 days after lotilaner administration.

https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/3101

Will never recover from the death of my dear late cat that was poisoned by one of these topical/oral flea products that was RX'd to her via a local veterinarian. She had symptoms very similar to/identical to this crap.

Just say no to E L A N C O !!!!



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Reply Recent Animal Drug Approvals (Original post)
CountAllVotes Feb 2018 OP
democratisphere Feb 2018 #1
CountAllVotes Feb 2018 #2
democratisphere Feb 2018 #3
CountAllVotes Feb 2018 #4
democratisphere Feb 2018 #5

Response to CountAllVotes (Original post)

Sat Feb 3, 2018, 02:55 PM

1. Stick with reputable companies like Bayer. It may cost more, but

the four legged family members are worth it!

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Response to democratisphere (Reply #1)

Sat Feb 3, 2018, 03:18 PM

2. ummmmmmm

E L A N C O is supposedly a "reputable" company.

Who cares that their products are offing dogs and cats?



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Response to CountAllVotes (Reply #2)

Sat Feb 3, 2018, 03:27 PM

3. Supposedly but apparently not.

I care and I certainly wouldn't use their products.

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Response to democratisphere (Reply #3)

Sat Feb 3, 2018, 06:47 PM

4. thank you

and my late cat thanks you too!

You'd be surprised how effective word of mouth is on this. Every person I tell the story to is horrified and says, "What can we do?".

I tell every person to tell 10 more people and to tell those people to tell 10 more.

At present, the vet that offed her is not doing so hot.

He is selling the crap at buy 6 and get 2 free! No takers much is seems!

Even the county sheriff knows! He said that obviously business isn't so hot! He too was sickened by what happened and ... the local shelter throws away anything that is donated to them that bears that name
E L A N C O on it!

Power to the people eh?


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Response to CountAllVotes (Reply #4)

Sat Feb 3, 2018, 06:59 PM

5. Your welcome. Thanks for posting your story!

Sorry for the loss of your family member and best friend.

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