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kristopher

(29,798 posts)
Tue Sep 13, 2016, 10:51 AM Sep 2016

Study: Sugar Industry Secretly Paid Harvard Researchers to Blame Fat for Health Risks

In 2007, Cristin Kearns was a general manager at Kaiser Permanente, where she ran a large group of dental practices. She was working with medical doctors at Kaiser to figure out ways they could provide better care for patients with diabetes, who are more likely to have gum disease. The work took her to a conference in Seattle focused on the links between the two diseases. As she watched the talks, attended the panel discussions, and read the materials handed out, she was struck by one thing: No one seemed to be talking about sugar. Even a pamphlet intended for diabetic dental patients didn’t suggest cutting back on sugar.

“I had this experience, which I found to be very strange, and I was wondering whether the sugar industry had an influence” on what was included in those patient materials, Kearns said in an interview. So she started digging. “I had a full-time job—research journalism wasn’t part of my job. I just was Googling at night after work.”

Today, as a postdoctoral researcher at the University of California, San Francisco, Kearns is publishing research based on the documents that her casual Googling led to: a trove of confidential documents, correspondence, and other materials that detail the relationship between the sugar industry and medical researchers in the 1960s and ’70s that UCSF has taken to calling the “Sugar Papers.”

Last year, she and her colleagues revealed that the sugar industry worked with the National Institutes of Health during those years to create a federal program to combat tooth decay in children that did not recommend limiting sugar consumption. On Monday, in a paper published in The Journal of the American Medical Association, Kearns details how in the 1960s, the leading sugar industry trade group paid three Harvard researchers nearly $50,000 in today’s dollars to publish a literature review that would link fat and cholesterol—and not sugar—to increased risk of heart disease.

The Sugar Research Foundation, which is now called the Sugar Association, “set the review’s objective, contributed articles for inclusion, and received drafts,” according to ...

https://www.yahoo.com/beauty/sweet-lies-sugar-industry-tricked-us-worrying-fat-233649580.html

Open access study published online: http://archinte.jamanetwork.com/article.aspx?articleid=2548255
September 12, 2016
Sugar Industry and Coronary Heart Disease Research
A Historical Analysis of Internal Industry Documents
21 replies = new reply since forum marked as read
Highlight: NoneDon't highlight anything 5 newestHighlight 5 most recent replies
Study: Sugar Industry Secretly Paid Harvard Researchers to Blame Fat for Health Risks (Original Post) kristopher Sep 2016 OP
At the time, researchers all over the country were noticing a generational increase Warpy Sep 2016 #1
That simply doesn't hold water; it's bunk and explicitly refuted by the evidence found. kristopher Sep 2016 #2
You're assuming one grant covered all research everywhere Warpy Sep 2016 #3
Write your opinion to Dr. Kearns, she is the one refuting your claim kristopher Sep 2016 #4
A more balanced perspective than the hype of today's "press." HuckleB Sep 2016 #5
That just tries to gloss over the corruption in academic research. kristopher Sep 2016 #6
No, it doesn't. HuckleB Sep 2016 #7
It's amazing how those who shout "science" loudest always go straight to personal attacks. kristopher Sep 2016 #8
Mr. Pot? Have you met Mr. Kettle? OKIsItJustMe Sep 2016 #9
Walking around muttering to yourself again? kristopher Sep 2016 #10
Muttering to myself, eh? OKIsItJustMe Sep 2016 #11
And we're still waiting kristopher Sep 2016 #12
This message was self-deleted by its author HuckleB Sep 2016 #13
Awww. That's cute. HuckleB Sep 2016 #14
Really?? kristopher Sep 2016 #15
The press, sir, is reporting on a peer-reviewed study. JackRiddler Oct 2016 #19
And the press did not give the full story. HuckleB Nov 2016 #20
That's some fantasy you have there. JackRiddler Nov 2016 #21
So when no fat started weight started going up. That is very telling! ScienceIsGood Sep 2016 #16
The glycemic index; the glycemic load kristopher Oct 2016 #17
Thanks for the great info. n/t ScienceIsGood Oct 2016 #18

Warpy

(111,250 posts)
1. At the time, researchers all over the country were noticing a generational increase
Tue Sep 13, 2016, 03:43 PM
Sep 2016

in the amount of arterial plaque deposits. It was a short but erroneous leap to blame it on animal fats, especially, since meat consumption had started to rise after the Great Depression and WWII had ended.

Unfortunately, they missed what else was happening, the appearance of trans fats that improved shelf life in the convenience foods that busy people everywhere were turning to.

Eventually the research was done, animal fats were declared preferable to trans fats, and we whole foods people were vindicated. Sort of.

While I'm sure the donation from the sugar industry sweetened the pot (ouch), I sincerely doubt it had much effect on the research that was ongoing. It seemed like a no brainer that fatty deposits were caused by fat. They just hadn't realized which kind.

kristopher

(29,798 posts)
2. That simply doesn't hold water; it's bunk and explicitly refuted by the evidence found.
Tue Sep 13, 2016, 06:17 PM
Sep 2016

Abstract from
Sugar Industry and Coronary Heart Disease Research
A Historical Analysis of Internal Industry Documents

Linked in OP


Early warning signals of the coronary heart disease (CHD) risk of sugar (sucrose) emerged in the 1950s. We examined Sugar Research Foundation (SRF) internal documents, historical reports, and statements relevant to early debates about the dietary causes of CHD and assembled findings chronologically into a narrative case study.

The SRF sponsored its first CHD research project in 1965, a literature review published in the New England Journal of Medicine, which singled out fat and cholesterol as the dietary causes of CHD and downplayed evidence that sucrose consumption was also a risk factor.

The SRF set the review’s objective, contributed articles for inclusion, and received drafts.

The SRF’s funding and role was not disclosed.

Together with other recent analyses of sugar industry documents, our findings suggest the industry sponsored a research program in the 1960s and 1970s that successfully cast doubt about the hazards of sucrose while promoting fat as the dietary culprit in CHD.

Policymaking committees should consider giving less weight to food industry–funded studies and include mechanistic and animal studies as well as studies appraising the effect of added sugars on multiple CHD biomarkers and disease development.


The academic environment today is even worse. The academic literature is chock full of industry sponsored, narrowly framed research that is DELIBERATELY designed to produce results which can be distorted. While there is internal validity to the work of these academics; all to often, like the work here, the external validity of the effort is sabotaged by design.

Warpy

(111,250 posts)
3. You're assuming one grant covered all research everywhere
Tue Sep 13, 2016, 06:26 PM
Sep 2016

and that researchers hadn't already come to the erroneous conclusion that increased dietary animal fat was causing an increase in fatty plaque deposits. Evidence about the harm of increased sucrose was coming from diabetes researchers, not cardiovascular researchers and it continued to increase. Eventually the twain met when metabolic syndrome was described.

The sugar lobby is powerful but not that powerful.

kristopher

(29,798 posts)
4. Write your opinion to Dr. Kearns, she is the one refuting your claim
Tue Sep 13, 2016, 06:52 PM
Sep 2016

You really, really need to learn how industries work to shape policy through academia.

kristopher

(29,798 posts)
6. That just tries to gloss over the corruption in academic research.
Wed Sep 14, 2016, 02:30 PM
Sep 2016

The idea that transparency is a firewall is bunk.

The idea that transparency is actually universally practiced is bunk.

Case in point - ethanol and all of the corn state universities.

What is needed is to cultivate ethics that include shunning of academics whose work is transparently crafted to play politics for corporations.

HuckleB

(35,773 posts)
7. No, it doesn't.
Wed Sep 14, 2016, 02:31 PM
Sep 2016

You seem to have preconceived notions that aren't open to discussion, and your history of wanting to ignore science makes your take here rather questionable, to be kind.

That's not really worth my time.

kristopher

(29,798 posts)
8. It's amazing how those who shout "science" loudest always go straight to personal attacks.
Wed Sep 14, 2016, 04:38 PM
Sep 2016

*That's in quotes because the process of science is virtually never present in their dialog.

kristopher

(29,798 posts)
10. Walking around muttering to yourself again?
Thu Sep 15, 2016, 12:43 PM
Sep 2016

Here you spend an entire thread engaging in nothing but personal attacks and misdirection.
How about answering the very, very legitimate question put to you?

http://www.democraticunderground.com/?com=view_post&forum=1127&pid=104917

kristopher

(29,798 posts)
12. And we're still waiting
Fri Sep 16, 2016, 12:11 PM
Sep 2016

...for your defense of hydrogen's requirement for significant additional generating infrastructure.

You've spent an untold amount of time and effort trying to avoid that issue, isn't it time to just act like a responsible adult and address it?

http://www.democraticunderground.com/1127104808



Response to OKIsItJustMe (Reply #9)

HuckleB

(35,773 posts)
14. Awww. That's cute.
Fri Sep 16, 2016, 04:58 PM
Sep 2016

Personal attacks are all the pseudoscience crowd ever offers, and there was no personal attack, in the first place.

Try a little intellectual honesty, and stop treating your fellow DUers like crap by spreading BS, and claiming "attack" when none has been made.

kristopher

(29,798 posts)
15. Really??
Fri Sep 16, 2016, 08:53 PM
Sep 2016

Your post 7:

No, it doesn't.
You seem to have preconceived notions that aren't open to discussion, and your history of wanting to ignore science makes your take here rather questionable, to be kind.
That's not really worth my time.

You wrote the post above and the comments are specifically intended to belittle me, the person. That was in lieu of an answer to the substance of the post I made. Note that none of the content is directed at you, the person, but instead relays a perception that is well accepted and widely acknowledged in academic circles. The solution is my belief.
. That just tries to gloss over the corruption in academic research.
The idea that transparency is a firewall is bunk.
The idea that transparency is actually universally practiced is bunk.
Case in point - ethanol and all of the corn state universities.
What is needed is to cultivate ethics that include shunning of academics whose work is transparently crafted to play politics for corporations.


After being called on that failure to address the arguments presented your response isn't to at least belatedly address the content of my post, it is to double down with more attempts to belittle me, the person.

Your post 14:
Personal attacks are all the pseudoscience crowd ever offers, and there was no personal attack, in the first place.
Try a little intellectual honesty, and stop treating your fellow DUers like crap by spreading BS, and claiming "attack" when none has been made.
 

JackRiddler

(24,979 posts)
19. The press, sir, is reporting on a peer-reviewed study.
Sun Oct 30, 2016, 06:45 PM
Oct 2016

Which is also linked in the OP. The press, for once, are doing their job of reporting. But that is all they are doing here.

HuckleB

(35,773 posts)
20. And the press did not give the full story.
Wed Nov 2, 2016, 07:52 PM
Nov 2016

As you know, but you are unwilling to acknowledge.

Why do you want to live in a fiction-based universe?

 

JackRiddler

(24,979 posts)
21. That's some fantasy you have there.
Thu Nov 3, 2016, 12:24 AM
Nov 2016

Based on the persona you present here, one would not expect you believe in remote viewing, telepathy, inner voice of the universe, or whatever else is deluding you into thinking you are inside my head, and know what I am thinking but withholding from you.

My guess is the power of projection.

kristopher

(29,798 posts)
17. The glycemic index; the glycemic load
Wed Oct 26, 2016, 02:28 PM
Oct 2016
Cardiovascular Disease & Diabetes

Updated:Mar 23,2016

The following statistics speak loud and clear that there is a strong correlation between cardiovascular disease (CVD) and diabetes.

At least 68 percent of people age 65 or older with diabetes die from some form of heart disease; and 16% die of stroke.
Adults with diabetes are two to four times more likely to have heart disease or a stroke than adults without diabetes.
The American Heart Association considers diabetes to be one of the seven major controllable risk factors for cardiovascular disease.

Why are people with diabetes at increased risk for CVD?


Diabetes is treatable, but even when glucose levels are under control it greatly increases the risk of heart disease and stroke. That's because people with diabetes, particularly type 2 diabetes, may have the following conditions that contribute to their risk for developing cardiovascular disease.

High blood pressure (hypertension)
High blood pressure has long been recognized as a major risk factor for cardiovascular disease. Studies report a positive association between hypertension and insulin resistance. When patients have both hypertension and diabetes, which is a common combination, their risk for cardiovascular disease doubles.

Abnormal cholesterol and high triglycerides
Patients with diabetes often have unhealthy cholesterol levels including high LDL ("bad&quot cholesterol, low HDL ("good&quot cholesterol, and high triglycerides. This triad of poor lipid counts often occurs in patients with premature coronary heart disease. It is also characteristic of a lipid disorder associated with insulin resistance called atherogenic dyslipidemia, or diabetic dyslipidemia in those patients with diabetes. Learn more about cholesterol abnormalities as they relate to diabetes.

more at: http://www.heart.org/HEARTORG/Conditions/Diabetes/WhyDiabetesMatters/Cardiovascular-Disease-Diabetes_UCM_313865_Article.jsp/#.WBD0R3dh2Rs


The glycemic index (GI) is a measure of the power of foods (or specifically the carbohydrate in a food) to raise blood sugar (glucose) levels after being eaten. The GI values of foods must be measured using valid scientific methods. It cannot be guessed by looking at the composition of the food. Currently, only a few nutrition research groups around the world provide a legitimate testing service. Professor Jennie Brand-Miller at the Human Nutrition Unit, Sydney University has been at the forefront of glycemic index research for over a decade, and her research group has determined the GI values of more than 2500 foods.

The GI value of a food is determined by feeding 10 or more healthy people a portion of the food containing 50 grams of digestible (available) carbohydrate and then measuring the effect on their blood glucose levels over the next two hours. For each person, the incremental area under their two-hour blood glucose response (glucose iAUC) for this food is then measured. On another occasion, the same 10 people consume an equal-carbohydrate portion of glucose sugar (the reference food) and their two-hour blood glucose response is also measured. A GI value for the test food is then calculated for each person by dividing their glucose iAUC for the test food by their glucose iAUC for the reference food. The final GI value for the test food is the average GI value for the 10 people.
http://www.glycemicindex.com/testing_research.php


Measuring carbohydrate effects can help glucose management

glycemix load


The glycemic index is a value assigned to foods based on how slowly or how quickly those foods cause increases in blood glucose levels. Also known as "blood sugar," blood glucose levels above normal are toxic and can cause blindness, kidney failure, or increase cardiovascular risk. Foods low on the glycemic index (GI) scale tend to release glucose slowly and steadily. Foods high on the glycemic index release glucose rapidly. Low GI foods tend to foster weight loss, while foods high on the GI scale help with energy recovery after exercise, or to offset hypo- (or insufficient) glycemia. Long-distance runners would tend to favor foods high on the glycemic index, while people with pre- or full-blown diabetes would need to concentrate on low GI foods. Why? People with diabetes can't produce sufficient quantities of insulin—which helps process blood sugar—which means they are likely to have an excess of blood glucose. The slow and steady release of glucose in low-glycemic foods is helpful in keeping blood glucose under control.

But the glycemic index tells only part of the story. What it doesn't tell you is how high your blood sugar could go when you actually eat the food, which is partly determined by how much carbohydrate is in an individual serving. To understand a food's complete effect on blood sugar, you need to know both how quickly the food makes glucose enter the bloodstream, and how much glucose it will deliver. A separate value called glycemic load does that. It gives a more accurate picture of a food's real-life impact on blood sugar. The glycemic load is determined by multiplying the grams of a carbohydrate in a serving by the glycemic index, then dividing by 100. A glycemic load of 10 or below is considered low; 20 or above is considered high. Watermelon, for example, has a high glycemic index (80). But a serving of watermelon has so little carbohydrate (6 grams) that its glycemic load is only 5.

To help you understand how the foods you are eating might impact your blood glucose level, here is a listing of the glycemic index and glycemic load, per serving, for more than 100 common foods...
http://www.health.harvard.edu/diseases-and-conditions/glycemic_index_and_glycemic_load_for_100_foods

A sampling from their list

FOOD Glycemic index (glucose = 100) Serving size (grams) Glycemic load per serving

Banana cake, made with sugar Glycemic index 47 60g load 14

Banana cake, made without sugar Glycemic index 55 60g load 12

...

Waffles, Aunt Jemima® Glycemic index 76 35g load 10

Bagel, white, frozen Glycemic index 72 70g load 25

...

Fruit Roll-Ups® 99 30 24

M & M's®, peanut 33 30 6

Microwave popcorn, plain, average 65 20 7

Baked russet potato 111 150 33

Boiled white potato, average 82 150 21

Hummus (chickpea salad dip) 6 30 0

Chicken nuggets, frozen, reheated in microwave oven 5 min 46 100 7

Pizza, plain baked dough, served with parmesan cheese and tomato sauce 80 100 22

Pizza, Super Supreme (Pizza Hut®) 36 100 9

Honey, average 61 25 12
http://www.health.harvard.edu/diseases-and-conditions/glycemic_index_and_glycemic_load_for_100_foods

From the same site:
The lowdown on glycemic index and glycemic load

If you have diabetes, you probably know you need to monitor your carbohydrate intake. But different carbohydrate-containing foods affect blood sugar differently, and these effects can be quantified by measures known as the glycemic index and glycemic load. You might even have been advised to use these numbers to help plan your diet. But what do these numbers really mean — and just how useful are they?

What these numbers measure

The glycemic index (GI) assigns a numeric score to a food based on how drastically it makes your blood sugar rise. Foods are ranked on a scale of 0 to 100, with pure glucose (sugar) given a value of 100. The lower a food's glycemic index, the slower blood sugar rises after eating that food. In general, the more cooked or processed a food is, the higher its GI, and the more fiber or fat in a food, the lower its GI.

But the glycemic index tells just part of the story. What it doesn't tell you is how high your blood sugar could go when you actually eat the food. To understand a food's complete effect on blood sugar, you need to know both how quickly it makes glucose enter the bloodstream and how much glucose it can deliver. A separate measure called the glycemic load does both — which gives you a more accurate picture of a food's real-life impact on your blood sugar. Watermelon, for example, has a high glycemic index (80). But a serving of watermelon has so little carbohydrate that its glycemic load is only 5.

Should you eat a low-GI diet?

Some nutrition experts believe that people with diabetes should pay attention to both the glycemic index and glycemic load to avoid sudden spikes in blood sugar. The American Diabetes Association, on the other hand, says that the total amount of carbohydrate in a food, rather than its glycemic index or load, is a stronger predictor of what will happen to blood sugar. And some dietitians also feel that focusing on the glycemic index and load adds an unneeded layer of complexity to choosing what to eat.

The bottom line? Following the principles of low-glycemic-index eating is likely to be beneficial for people with diabetes. But reaching and staying at a healthy weight is more important for your blood sugar and your overall health.

If you'd like to give low-glycemic-index eating a try, click here to see our table of the glycemic index and load for over 100 common foods.

And for more information on how to live well — and eat well — with type 2 diabetes, buy Healthy Eating for Type 2 Diabetes, a Special Health Report from Harvard Medical School.

Updated: September 26, 2016
Originally published: May 2016
http://www.health.harvard.edu/diseases-and-conditions/the-lowdown-on-glycemic-index-and-glycemic-load
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