The story begins in 1970, when Frampton and his old band Humble Pie scored a gig playing two sets a night at the Fillmore West in San Francisco. Frampton says the first night was a rough go: The guitar he was using fed back at loud volumes and made soloing a chore. After the show, an audience member approached him and offered to help.
"He said, 'Well, look, I have a Les Paul that I've sort of modified myself a little. Would you like to try it tomorrow?'" Frampton tells weekends on All Things Considered host Guy Raz. "I said, 'Well, I've never really had much luck with Les Pauls, but you know what? At this point, I'll try anything.'"
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That guitar — a shiny black number with an added pickup — became Frampton's signature instrument. He continued to use it with Humble Pie, and in his solo material, played it almost exclusively for years. It even made the cover of his classic 1976 live album, Frampton Comes Alive!

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In 1980, while Frampton was on tour in South America, the guitar was put on a cargo plane in Venezuela, en route to Panama. The plane crashed right after takeoff.
"Basically I'm thinking, 'It's gone,'" Frampton recalls. "But the thing is, I'm also sitting in a restaurant where I can see the pilot's wife. She's waiting in the hotel for her husband, who, unfortunately, didn't make it. So we were all overcome, because people lost their lives as well as our complete stage of gear."
What Frampton didn't know is that the guitar had survived....
Read more:
http://www.npr.org/2012/01/07/144799712/framptons-dream-guitar-recovered-decades-later
Or Listen:
http://www.npr.org/player/v2/mediaPlayer.html?action=1&t=1&islist=false&id=144799712&m=144840341

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