DocwillCuNow
DocwillCuNow's JournalAlzheimer's type dementia clinical trial, still recruiting
http://www.clinicaltrials.gov/ct2/show/NCT01479855?term=alzheimer%27s+vitamin+d&rank=7The purpose of the study is to compare the concentrations of Vitamin B1 (thiamine), Vitamin B6 (pyridoxal-5-phosphate), folate, Vitamin B12 (cobalamin), Vitamin C (ascorbic acid), Vitamin A (retinol), Vitamin E (alfa-tocopherol), homocystein, uric acid, F2 8-?-isoprostane, 8-deoxyguanosine, retinoids, tau-protein and ?-amyloid in spinal fluid, metabolomics, proteomics, m-RNA for DNA repair enzymes and DNA in patients who suffer from mild cognitive impairment (MCI) or mild dementia of Alzheimers type, with healthy controls.
A second aim is to explore the association between vitamin and nutrient reductions, if any, and cognitive function as well as vascular score and possible changes in the MRI.
Question submitted by DocwillCuNow
Curing rheumatoid arthritis in mice: Antibody-based delivery of IL4
http://www.sciencedaily.com/releases/2014/08/140806102806.htmDate:
August 6, 2014
Source:
ETH Zurich
Summary:
With a new therapeutic product, researchers have managed to cure arthritis in mice for the first time. The scientists are now planning to test the efficacy of the drug in humans. Rheumatoid arthritis is a condition that causes painful inflammation of several joints in the body. The joint capsule becomes swollen, and the disease can also destroy cartilage and bone as it progresses. Rheumatoid arthritis affects 0.5% to 1% of the world's population
Rheumatoid arthritis is a condition that causes painful inflammation of several joints in the body. The joint capsule becomes swollen, and the disease can also destroy cartilage and bone as it progresses. Rheumatoid arthritis affects 0.5% to 1% of the world's population. Up to this point, doctors have used various drugs to slow or stop the progression of the disease. But now, ETH Zurich researchers have developed a therapy that takes the treatment of rheumatoid arthritis in mice to a new level: after receiving the medication, researchers consider the animals to be fully cured.
The drug is a biotechnologically produced active substance consisting of two fused components. One component is the body's own immune messenger interleukin 4 (IL-4); previous studies have shown that this messenger protects mice with rheumatoid arthritis against cartilage and bone damage. ETH scientists have coupled an antibody to IL-4 that, based on the key-lock principle, binds to a form of a protein that is found only in inflamed tissue in certain diseases (and in tumour tissue).
Localized drug delivery
"As a result of combination with the antibody, IL-4 reaches the site of the disease when the fusion molecule is injected into the body," says pharmacist Teresa Hemmerle, who has just completed her dissertation in the group of Dario Neri, a professor at the Institute of Pharmaceutical Sciences. Together with Fabia Doll, also a PhD pharmacist at ETH, she is the lead author of the study. "It allows us to concentrate the active substance at the site of the disease. The concentration in the rest of the body is minimal, which reduces side-effects," she says.
Link between vitamin D, dementia risk confirmed (sciencedaily)
From the "not this s**t again arena. Release the hounds.
http://www.sciencedaily.com/releases/2014/08/140806161659.htm
Link between vitamin D, dementia risk confirmed
Date:
August 6, 2014
Source:
University of Exeter
Summary:
Vitamin D deficiency is associated with a substantially increased risk of dementia and Alzheimer's disease in older people, according to the most robust study of its kind ever conducted. An international team found that study participants who were severely vitamin D deficient were more than twice as likely to develop dementia and Alzheimer's disease.
An international team, led by Dr David Llewellyn at the University of Exeter Medical School, found that study participants who were severely Vitamin D deficient were more than twice as likely to develop dementia and Alzheimer's disease.
The team studied elderly Americans who took part in the Cardiovascular Health Study. They discovered that adults in the study who were moderately deficient in vitamin D had a 53 per cent increased risk of developing dementia of any kind, and the risk increased to 125 per cent in those who were severely deficient.
Similar results were recorded for Alzheimer's disease, with the moderately deficient group 69 per cent more likely to develop this type of dementia, jumping to a 122 per cent increased risk for those severely deficient.
I loved my mittens, but no more....
Had to share, saw this today and almost got caught by an elderly gentleman as he was coming out of the store.... either he tried to scrape it off, stepping in dog poo comes to mind, or some democrat put the blue to it, either way I was chuckling when I saw it. Buyers remorse as they say.
I work with my hands
I work with my hands. I sweat each and every day, I often do hard physical work and have done so for over 40 years. This is an indisputable fact. I do work for my age that pretty much belongs to the 20-40 year old workers. I do not, have not, nor (most likely) will I ever sell anything, anywhere, period. Those convinced otherwise are severely mistaken.
I posted something that on the surface appears to be some sort of sales gimmick, it was not. When my dad took ill a long time ago, a victim of pesticides (DDT/Monsanto) and Philip Morris, he was simply chemoed and radiated until the end. In those days, little was known about strengthening the immune system, antioxidant protection, etc. Dad died a horrible death, literally suffocating to death. Then it rings in your head, if I knew then what I know now, and damn it why didn't I.
Now, with another family member critically ill with fungal meningitis, see the great meningitis outbreak of 2012 for information on the tainted steroids that were distributed and used on thousands of people across several states. http://www.cdc.gov/hai/outbreaks/meningitis.html
I do not know if our family member received one of these shots or not but at this point it doesn't matter. I was, out of frustration, trying to put out there examples of people who through unorthodox means, means that most hospitals and physicians would laugh at or say :that is voo doo medicine etc." I am hoping that by giving these examples of what some would refer to as miracles that others will take note and give it a try, it is in their own literature as exampled by the site that explains the New Zealander who made it through the viral pneumonia and the hairy cell leukemia.
Here is the gold standard of proof.
http://healthimpactnews.com/2013/vitamin-c-saves-man-dying-of-viral-pneumonia/
>>Three Randomized Placebo Controlled Studies
Apparently Dr Galler is unaware of three double blind placebo controlled studies of IV Vitamin C in critically ill patients in the ICU. These studies were published in Dr. Galler’s own peer-reviewed specialty medical literature. (1-5)
These three studies showed reduced mortality and reduced time on ventilators for septic and critically ill patients in the ICU setting. In addition, numerous other studies have measured blood vitamin C levels in critically ill patients in the hospital showing vitamin C is typically depleted with levels below 25 % of healthy individuals.(6-11) As Dr Levy points out in Part Four of the Series (see below), there are thousands of studies over 70 years in the medical literature showing effectiveness, and safety of vitamin C for viral illness. Dr Levy’s cites 1200 such articles supporting the use of Vitamin C.
The chart below is from Nathens et al , showing serum vitamin C levels in critically ill surgical patients. The red line shows subnormal blood vitamin C values in untreated patients. The green line shows high normal blood vitamin C values in patients treated with IV vitamin C. The normal range is 0.5 to 2.0 ng/dl. Vitamin C treated patients (green line) had less pulmonary morbidity, less multi-organ failure and less ventilator dependency when compared to untreated patients (red line).<<
I have a family member who may die or become severely disabled by the illness he is facing. He has been in the ICU, he is not doing well. What I hope in some sort of bizarro way is that exposure of the Alan Smith story will somehow prod some doctor somewhere to do what goes against his instincts, and hopefully one of those doctors will be involved with my family members case. I know this is a huge exercise in futility however there is nothing more I can do to intervene. Apologies to those who were offended by the post, apologies to the mods, jurors and executioners who may have had to wring their hands trying to decipher my motives. I shall not do it again, I appreciate their allowing me to say what I had to say in a feeble effort to affect a loved ones chances for survival. Thank you all, I will not do it again.
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