That annoys me. Not to mention that the manufacturer walks right up to the line of saying it is "FDA-Approved for memory loss." It is NOT.
The ridiculously small self-funded study it refers to as "evidence of its effectiveness is summarized on a pretty lay term basis here:
The evidence to support Prevagen’s use is limited and flawed. Quincy Bioscience published a small study in 2016 comparing 10 mg of apoaequorin per day to placebo (a pill with no medication in it) for 90 days. All study participants self-identified as having memory problems, but none had any serious memory loss conditions like Alzheimer’s disease or dementia.
At the end of the study, people taking apoaequorin had higher scores than those taking placebo on some of the tests used to measure their overall memory. The study authors noted the difference between the two groups was significant, and Quincy Bioscience — who also sponsored the study — has been using these results to back up Prevagen’s claims.
But there are a few issues with the study. First, it only included a little over 200 participants and only ran for 90 days. This number of people is smaller than what we typically require when trying to prove a medication is effective for the general population. Also, conducting the study for only 90 days means we don’t know the long-term safety or effectiveness of Prevagen.
Another problem with this study is the types of tests the researchers used to test memory. None of the cognitive assessments used in this study are standard tests used by healthcare providers to look for and diagnose memory loss conditions. Using a non-standard test makes the results difficult to interpret, so we can’t say for sure just how effective Prevagen is.
https://www.goodrx.com/well-being/supplements-herbs/prevagen-for-memory-loss-claims
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