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Response to Raine (Reply #51)

Wed Apr 7, 2021, 06:07 AM

53. Sorry to burst your bubble, but no clear evidence of cross-protective immunity to different strains

While immunity is believed to be at least 4 years to the strain of Norovirus causing original infection, but we really don't know if that applies to the other genotypes of Norovirus (NoV) That is but one of the challenges to creating vaccines against NoV. Since most of what we know comes from challenge studies (where individuals are actually intentionally infected with far higher doses than is necessary for natural infection--NoV requires an incredibly low dose in real-world infection), the duration of immunity may be less and far more limited.

All the more reason to take surface disinfection seriously, especially during winter months or in crowded settings.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410000/

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LineLineLineNew Reply Sorry to burst your bubble, but no clear evidence of cross-protective immunity to different strains
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