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BumRushDaShow

(127,271 posts)
30. Yes - they started working on them back in 2003
Mon Jul 26, 2021, 01:54 PM
Jul 2021

Pfizer and Moderna were both part of Operation Warp Speed. But because Pfizer has deep pockets, they didn't request any grants for research but still got an almost $2 billion government contract and Moderna did get seed money from the government since they were working with NIH personnel on the research and development of the vaccine candidates to be evaluated -

Trump Administration Selects Five Coronavirus Vaccine Candidates as Finalists

By Noah Weiland and David E. Sanger
Published June 3, 2020Updated July 27, 2020

WASHINGTON — The Trump administration has selected five companies as the most likely candidates to produce a vaccine for the coronavirus, senior officials said, a critical step in the White House’s effort to deliver on its promise of being able to start widespread inoculation of Americans by the end of the year.

By winnowing the field in a matter of weeks from a pool of around a dozen companies, the federal government is betting that it can identify the most promising vaccine projects at an early stage, speed along the process of determining which will work and ensure that the winner or winners can be quickly manufactured in huge quantities and distributed across the country.

The announcement of the decision will be made at the White House in the next few weeks, government officials said. Dr. Anthony S. Fauci, the federal government’s top epidemiologist and director of the National Institute of Allergy and Infectious Diseases, hinted at the coming action on Tuesday when he told a medical seminar that “by the beginning of 2021 we hope to have a couple of hundred million doses.”

The five companies are Moderna, a Massachusetts-based biotechnology firm, which Dr. Fauci said he expected would enter into the final phase of clinical trials next month; the combination of Oxford University and AstraZeneca, on a similar schedule; and three large pharmaceutical companies: Johnson & Johnson, Merck and Pfizer. Each is taking a somewhat different approach.

(snip)

https://www.nytimes.com/2020/06/03/us/politics/coronavirus-vaccine-trump-moderna.html


Merck's initial attempt failed so they pulled out and had planned to partner with another vaccine maker since they have some new facilities designed to manufacture vaccines, but has now mainly shifted to work on supplying an anti-viral product.

Sanofi-GSK, who was not part of Operation Warp Speed also had issues with their first attempts and were to supposedly be planning to submit for EUA by the end of the year, and have their product currently under review in the EU.

You also have NovaVax who plans to submit data by the fall.

But note that doing the approvals is not just a review of the clinical data by ACIP (CDC) or VRBPAC (FDA). There is a review of the actual manufacturing and quality control processes that need to happen through inspections of the plants, and looking at sterility and other conditions.

And regarding that latter process, that is how they found out about the problems with Emergent BioSolutions - https://www.usatoday.com/story/news/nation/2021/04/21/covid-19-fda-issues-withering-report-us-factory-making-j-j-vaccine/7319674002/

Emergent had been contracted to produce Janssen's (J&J's) vaccine here in the U.S. that was actually being manufactured in Belgium and shipped from overseas, and AstraZeneca's vaccine, that was being manufactured in the UK and Sweden.
How did we get to the point where this wasn't a "NO BRAINER" at the earliest opportunity? bucolic_frolic Jul 2021 #1
It's because the bizarre, outlandish, and conspiratorial BumRushDaShow Jul 2021 #3
Because the Covid vaccine is still under "Experimental Use" LeftInTX Jul 2021 #12
That collection bucolic_frolic Jul 2021 #13
I have read some strange responses to news articles on Facebook... LeftInTX Jul 2021 #14
Emergency Use Authorization. Claire Oh Nette Jul 2021 #25
Then they can make it mandatory for doctors, nurses, other healthcare officials LeftInTX Jul 2021 #36
I've looked into the vaccine mandate issue a little. Tomconroy Jul 2021 #2
"Apparently it comes from a post 9/11 law." BumRushDaShow Jul 2021 #9
There's an article about this here: MisterNiceKitty Jul 2021 #16
Some people have that opinion. Others do not. Tomconroy Jul 2021 #20
True, you know I meant to point that out MisterNiceKitty Jul 2021 #21
Some big name colleges are mandating vaccines Tomconroy Jul 2021 #23
I do believe those "mandates" are in anticipation of full FDA approval by the Fall MisterNiceKitty Jul 2021 #26
Here's one: Tomconroy Jul 2021 #29
And my own Little Ivy League school: Tomconroy Jul 2021 #33
And from a school almost as good! Tomconroy Jul 2021 #34
Clean sweep among the Little Three! Tomconroy Jul 2021 #35
Yes & thanks MisterNiceKitty Jul 2021 #37
Ithink the number of those states is now up to 20. Tomconroy Jul 2021 #39
Also per CNN MisterNiceKitty Jul 2021 #38
NYC had a nice little wrinkle today: Tomconroy Jul 2021 #40
as it should be in a sane USA!! riversedge Jul 2021 #4
i thought that ALL health people were to get vaxxed first when the vaxx AllaN01Bear Jul 2021 #5
Some of them chose not to get it IronLionZion Jul 2021 #7
They were literally at the top of the list and front of the line BumRushDaShow Jul 2021 #11
Anti-vax healthcare workers are the worst IronLionZion Jul 2021 #6
There is no mandate for covid Quakerfriend Jul 2021 #8
Good idea! BlueWavePsych Jul 2021 #10
When it's fully approved, it has the effect of having law behind it and it can then be required. lark Jul 2021 #15
Interestingly enough, the same goes for the military BumRushDaShow Jul 2021 #17
How long before it's fully approved? And what's standing in the way of that? catrose Jul 2021 #18
I read yesterday that it will take 2 more months for full approval. lark Jul 2021 #19
"How long before it's fully approved? And what's standing in the way of that?" BumRushDaShow Jul 2021 #22
Mumps, 1967, took four years to develop Claire Oh Nette Jul 2021 #27
Yes - they started working on them back in 2003 BumRushDaShow Jul 2021 #30
Thanks for the detail. Claire Oh Nette Jul 2021 #31
You are welcome BumRushDaShow Jul 2021 #32
Only makes sense. Yo_Mama_Been_Loggin Jul 2021 #24
For those with an interest, here is a link Tomconroy Jul 2021 #28
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