rather than taking a chance on someone who has been unemployed for some time. It's very difficult for the long term unemployed to even get interviews. Gratitude is a great attitude. Expressing negativity towards anything can be a big turnoff in job interviews.
Rather than being unhappy with my current job, I state that the company's major organizational changes are heading in a different direction from where I would like to go. Or vice versa, I see my career heading in a different direction or I want to leverage different skillsets than what they have me doing.
If you have been training and building up new skills in the work you want, put that right on the top. The stuff you want to go into should be the first thing anyone sees on your resume before going down to your work experience. That worked for me.
I recently got a new job offer after years of passively searching while I had a soul sucking job in the wrong field with multi-hour commutes to different cities. I'm nothing special, so it can be done by anyone. An optimistic attitude makes a big difference.
Good luck to all! 
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