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Science

Botany

(70,501 posts)

6. On Remdesivir ... in 1,090 test cases it dropped the mortality rate from 11.6% to 8.0%

Reply to NNadir (Original post)

Thu Apr 30, 2020, 10:17 AM

Apr 2020

Results from the preliminary trial show remdesivir improved recovery time for coronavirus patients from 15 to 11 days. That's similar to the effect that the influenza drug Tamiflu has on flu. Tamiflu also doesn't cure patients quickly, but can reduce how long they are sick.
"Although a 31% improvement doesn't seem like a knockout 100%, it is very important proof of concept," Fauci said of remdesivir.

"What it has proven is that a drug can block this virus."

Remdesivir also may reduce the likelihood that patients will die.

"Results also suggested a survival benefit, with a mortality rate of 8.0% for the group receiving remdesivir versus 11.6% for the placebo group," the NIAID said.

https://www.cnn.com/2020/04/29/health/gilead-sciences-remdesivir-covid-19-treatment/index.html

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Clinical Improvement in Covid Remdesivir Double Blind Study Is Not Statistically Significant. [View all] NNadir Apr 2020 OP

I understand that Gilead has ties with Kushner.. That is all we need to know secondwind Apr 2020 #1

yeah, but then it means NJCher Apr 2020 #3

It most assuredly does NOT mean that. The study to which I referred did not rule out... NNadir Apr 2020 #11

so were you aware of what Fauci said when you wrote this post? NJCher Apr 2020 #13

I did not review exactly what he said, but heard it by osmosis. The news item leading to the... NNadir Apr 2020 #16

There is a very valid scientific reason for evaluating this drug in Covid. NNadir Apr 2020 #5

That was my first guess when I heard 15 days shortened to 11 days unblock Apr 2020 #2

Also a nice look over there moment for Trump when he's getting pummeled. gibraltar72 Apr 2020 #4

A few things. Igel Apr 2020 #14

On Remdesivir ... in 1,090 test cases it dropped the mortality rate from 11.6% to 8.0% Botany Apr 2020 #6

We'll see. The study to which I referred did not say the drug didn't have any effect... NNadir Apr 2020 #9

Time will tell. With more numbers treated, it may well reach statistical signficance hlthe2b Apr 2020 #7

after working in big pharma for 25 years, I looked at the data NRaleighLiberal Apr 2020 #8

And that is the reason, the FDA always assembles a committee of scientists to review the data. NNadir Apr 2020 #18

Note: STOPPED early because of adverse events 12% versus 5% in placebo. . . nt Bernardo de La Paz Apr 2020 #10

That's the impression I had as well reading this. drray23 Apr 2020 #12

Also, it appears that "adverse effects" were more than double in the Remdesivir group... Sancho Apr 2020 #15

Every drug has side effects. This one, since it acts on nucleic acid synthesis... NNadir Apr 2020 #17