Reply #117: Could be.

[Vektor]

There is a black lab in our neighborhood who is very mean to cats, and she's just a sweet ol' gal with everyone else. I think maybe she just never had exposure to them, and when she sees one on the street, thinks it's a small prey to chase.

The owner keeps her on a short leash and has NO idea why she acts that way, other than guessing she's never lived with a cat before, so maybe that has something to do with it.