Cold Sore Virus Linked To Alzheimer's Disease: New Treatment, Or Even Vaccine Possible

[FarCenter]

Source: Science Daily


ScienceDaily (Dec. 7, 2008) — The virus behind cold sores is a major cause of the insoluble protein plaques found in the brains of Alzheimer's disease sufferers, University of Manchester researchers have revealed.

They believe the herpes simplex virus is a significant factor in developing the debilitating disease and could be treated by antiviral agents such as acyclovir, which is already used to treat cold sores and other diseases caused by the herpes virus. Another future possibility is vaccination against the virus to prevent the development of the disease in the first place.

Alzheimer's disease (AD) is characterised by progressive memory loss and severe cognitive impairment. It affects over 20 million people world-wide, and the numbers will rise with increasing longevity. However, despite enormous investment into research on the characteristic abnormalities of AD brain - amyloid plaques and neurofibrillary tangles - the underlying causes are unknown and current treatments are ineffectual.

Professor Ruth Itzhaki and her team at the University's Faculty of Life Sciences have investigated the role of herpes simplex virus type 1 (HSV1) in AD, publishing their very recent, highly significant findings in the Journal of Pathology.


Read more: http://www.sciencedaily.com/releases/2008/12/081207134109.htm

[Tangerine LaBamba]

1. It didn't used to be called Alzheimer's, right?

Wasn't it just "senility"?

[DJ13]

2. Wasn't it just "senility"?

I dont remember.

[Tangerine LaBamba]

8. HAHAHAHA!!!

Thank you. That really caught me and caused me to explode. Messy here now.

Good one.

:toast:

[pitohui]

3. there are many kinds of senility

such as age-related memory loss

this is a specific form of senility, it's more than just slowing down and not being able to win at jeopardy any more, you forgot how to eat or even that you just ate, you forget the name of your own children and how to go to the bathroom

[Tangerine LaBamba]

10. Oh, thank you.

I do know what Alzheimer's is, having just spent a lot of time with Alzheimer's patients in all stages.

I'm just wondering, though, if senility was what we called it back when I was a kid - a long time ago - when people didn't live as long as they do now, and perhaps "senility" didn't progress as far as it does now.

It is awful to witness. I hope it's not awful to endure. I hope those people are peaceful inside.

[pitohui]

25. don't thank me, actually read my post, that\'s all the thanks i want, i did ans. yr question

the answer is NO, senility is a general term, alzheimer's is a specific term -- i've had relatives with both and there's a huge difference between just gradually getting a little "slower" and alzheimer's, the difference in some cases between being able to keep your home until you die and being utterly helpless and unable to understand what is happening to you in the nursing home

when someone is screaming at you because they think you're starving him, because he can't remember you fed him 10 minutes ago, unfortunately it's safe to say that they're not somehow magically "peaceful" on the inside

of course alzheimer's is awful to endure, as it's in my family, my only wish is that the laws change so that when/if i get it, i can be put quietly to sleep instead of beggaring those who love me to pay for my torture

there are forms of senility that are "softer" where the person just loses their edge and gets ripped off more than they should by fuck-wits or just make rather poor decisions they wouldn't had made when younger but the difference is still night and day

admittedly there is a point where the person is not yet diagnosed with alzheimers but is already making poor judgments -- that's the time when you don't know whether it's just the natural waning of one's sharpness or if it's just the beginning of the terrible journey

[Tangerine LaBamba]

32. You didn't read my post carefully,

or you'd have responded differently.

I've got a lot of experience with people who are Alzheimer's patients. And it is regretful that it's in your family, as I am sad that it is in mine.

But, my point was that when I was a child, a long time ago, old people became senile, but there weren't any who went so far as the Alzheimer's patients I've known, and I wonder if the longer life span is something that contributes to this progression.

In short, is Alzheimer's simply an extension of what used to be called senility?

I'll ask some geriatric specialists I know. To do this on a message board is clearly a sign of my own impending senility.

Thanks anyway.

[pitohui]

39. i see you wish it otherwise, as do we all, but the answer to your question is still NO

alzheimer's disease is STILL not automatically the "senility" you knew as a child -- there are many kinds of senility, alzheimer is only one of them

you may have known, as a child, people who were senile who had alzheimer's but you may also knew people who were senile who didn't have alzheimer's -- at this distance it is impossible to say which

while your risk of alzheimer's increases with age, alzheimer's is caused by a gene

many people have early onset alzheimers -- a famous example would be john james audubon -- there are people who have alzheimer's in their 50s and 60s and always will be until we get a cure

alzheimer's is a SPECIFIC disease, senility is a GENERAL category of diseases and BOTH the general category and the specific disease have always existed

how do you work in health care and have this in the family and not know this except out of fear? look, i'm afraid too, desperately afraid, but it isn't the definitions and the words that will hurt us

if you don't have the alzheimer's gene, there are other forms of senility that can hurt you -- example, senility from age related memory loss, another example, senility caused by a stroke (i've seen people recover significant function from this one), etc.

please ask elsewhere and verify this information since you don't trust the answer you get here

but the answer won't change, no one knows what kind of senility the people you knew who were senile as a child, but we DO know that the awful disease of alzheimer's existed at least as far back as audubon's day as he is a classic and horrific example of early onset alzheimer's

[Tangerine LaBamba]

42. No one knows what causes it

Genetic markers are one theory - but only a theory.

You do use a lot of words, but, again, you obviously weren't able to understand what I wrote. You surely have things you like to write, but, alas, there is no communication here.

This is now no longer worth pursuing. Your language is not my language.

Good luck.

[pitohui]

53. it's genetic, i too wish it were not so, but it is

no amt of saying it isn't so will make it otherwise

read the article carefully, virtually the entire pop. is infected w. the virus in question (which people know already, since it's the very infamous herpes simplex virus 1!), those who have the genetic weakness will have an issue, those who don't...well they are the ones who don't get it

i think that's putting it in english words of one syllable -- truly if you don't understand that it's because you don't want to (believe me i understand why you don't want to)

no one wants to believe that they could develop a disease like this or that they could inherit it thru no fault of their own, people only get sick eating the bad food or fucking the bad boy, i know, i know...but that's a fantasy

alzheimer's is a genetic thing, like your height, your weight, your gender, you inherited it like it or not

[harpboy_ak]

57. Not always genetic

There are 2 kinds of Alzheimers: genetic-related Alzheimers, which is usually early onset AD, and non-genetic related AD, the cause or causes of which are only now starting to be discovered. So your statement really is a pit of hooey, since only a small portion of AD is genetic related.

To respond to other questions, the correct term is not "senility", it's "dementia". AD is only one of the common types of dementias; others include frontal lobe dementias (which can cause loss of inhibitions) and Lewy Body dementia. There are also dementias caused by strokes, blocked carotid arteries, hypoxia --- lack of oxygen, often due to COPD (aka emphysema), and several forms of hydrocephalus (fluid disorders that create pressure on the brain).

For complete information about dementias, check "The 36 Hour Day" by Mace & Rabin.

[Tangerine LaBamba]

65. Genetic or a virus?

And now a virus is genetic? You're stumbling over your own ideas.

I think you want to believe something and make it understandable for your own comfort. I wish you luck. Being scared is an awful way to go through life.

[Lydia Leftcoast]

72. No, there were people with Alzheimer's when I was a kid in the 1950s

I remember some cases from among my parents' friends and people in the neighborhood, people who exhibited clear symptoms of what we now call Alzheimer's, only we didn't distinguish among different types of dementia in those days, at least not outside the medical community.

[Tangerine LaBamba]

77. Exactly

That's what I was wondering. In my neighborhood, also in the fifties, there were families that had a Granny or an Aunt Mary upstairs in a bedroom with a door that was always closed, and sounds that escaped that scared the life out of us. We were told that Granny and Aunt Mary were old and sick, and that was that. To us kids, it was normal.

And it was called "senile."

That was my point, thank you for recognizing it. The pathology existed, but there was no other name for it. And there surely wasn't the amount of money going into research for it as there is now simply because the life span was shorter.

Amazing how rabid and off the wall some people get over a simple question.

[Coventina]

5. You've obviously never had a loved one with Alzheimer's or

any other form of dementia.

Count yourself lucky.

[Tangerine LaBamba]

11. And you're obviously

making assumptions out of nothing.

My aunt passed away two months ago after a years-long struggle with Alzheimer's. I spent almost a year in a nursing home with many Alzheimer's patients.

So take your sanctimonious and erroneous assumption, and shove it.

[Coventina]

14. "shove it"? Wow, nice.

You were the one showing the flippant attitude toward a disease that destroys entire families.

Sorry I made the assumption that you wouldn't be so cavalier about a disease that took a family member that was close to you.

Alzheimer's & related diseases are HELL for the victims & their families. I'm glad that you can laugh about it. I sure can't.

[Tangerine LaBamba]

17. "... flippant attitude...."?

How did you get "flippant" out of a simple question?

It's your perspective that's questionable, pal, and if a simple question spells "flippant" to you, then you're far too messed up for me to consider in any meaningful way.

Shame on you and your holier-than-thou attitude in light of a simple query. You're so special, you're the only one who's ever had any kind of hard times in your life.

Yes, shove it.

And now I'm sure you'll be busy pounding out responses to the people who made jokes in response to my query. Aren't they worthy of your mighty scorn, and don't you want to hurry and scold them for being "flippant"?

You total ass.

Edited to add that you're on Ignore. Who needs nonsense like yours?

[Coventina]

19. As a matter of fact, I do find jokes about devastating diseases

to be extremely distastful, in reference to some of the other posts on this thread. It was your initial post that sparked the others, so they apparently read your "simple question" as a joke as well.

[qazplm]

23. we laugh about death and disease all the time

and there is nothing wrong with it.

Like with everything else there is a time and place for it.

[Coventina]

30. That's fine as long as the joker understands that if it's done

in public (like on a message board) and within "hearing" of people that are hurting, they may not get a positive response.

[panader0]

6. I've heard it called CRS; Can't Remember Shit

Edit to add: My father was a victim.

[Tangerine LaBamba]

12. Some of it can be interesting

I knew a woman, 92 years old, lost in dementia, widow of a preacher man.

Every night, around 2 am, she'd start preaching at the top of her lungs. My favorite line came from her one night when she pronounced that "George Washington, who was the King of Egypt, lay down with the King of the Jews and brought forth Hitler."

[wildflower]

50. I've wondered the same thing

If the dementias we see now are new, or if they used to get lumped in with the term "senile" in the old days.

And if they are new, if it is because people are living longer.

[FlaGranny]

62. "Senile" dementia

covers Alzheimer's and also other kinds of dementia. Multi-infarct dementia is another type of senile dementia, which is caused by a series of small strokes.

It is not new. You might be interested in this: http://alzheimers.about.com/cs/caregivers/a/Alois_Alzheimer.htm

[wildflower]

66. I'm aware of the different types of dementias, but thanks for the link

The question is about what these dementias used to be called - whether they were all called "senility" - before people were aware of the different types.

As for Alzheimer's specifically, the question is, did that begin to occur as a result of environmental or other changes, or was it always there, but MRIs didn't exist to diagnose it. Or did we not see it show up very much because the human lifespan used to be much shorter.

(Edited to add more explanation)

[Tangerine LaBamba]

71. Thank you

You are the only person who read and understood my very simple question. Thank you for your clarity.

I was absolutely baffled by the kinds of responses that simple question elicited, but I suppose folks have their own agendae and need to say things that would probably go unheard in their real worlds.

The lack of reading comprehension at DU is very often a source of real mirth.

Again, thanks.

[wildflower]

73. You're welcome

I felt you were being misunderstood there.

I think somehow we were interpreted as if we were calling it senility, rather than saying that others in centuries past may have.

[FlaGranny]

75. All the dementias were called "senile"

and they mostly always were. The article I linked explains that Alzheimer was not the first to describe this particular type that we now call Alzheimer's. Others before him also noticed this type of dementia, but it was named after Alzheimer in 1906 - so this form has been around well over 100 years, but probably much longer. Senile dementia was first being discussed about 200 or so years ago. If we were looking for an environmental cause, that cause would have had to be present 200 years ago. My guess is that not very many people 200 years ago lived to be old enough to become demented so it was relatively uncommon. The industrial revolution in the 1700s with the increased use of coal and increased pollution is the only thing I could think of at that time that could be an environmental causative factor, not to say there might not be others.

[mainer]

4. Time to invest in Acyclovir?

This is pretty interesting.

[FarCenter]

9. I'd think that it is off-patent

Not pot of gold there.

Invented by Gertrude B. Elion, woman pharmacologist. Nobel Prize winner in 1988, and first woman to be inducted into the National Inventors Hall of Fame.

http://en.wikipedia.org/wiki/Gertrude_B._Elion

[HysteryDiagnosis]

7. Time to realize that all things infectious are not without some sort

of agonist in nature.


http://altmedicine.about.com/cs/supplements/a/ColdSores.htm

#
Resveratrol

Resveratrol, a compound found naturally in red grapes, has been shown to be active against the herpes simplex virus in laboratory studies.

A study by the Northeastern Ohio University demonstrated that resveratrol cream applied topically two, three, or five times a day effectively suppressed cold sore development if it was applied one or 6 hours after infection with the herpes virus.

Resveratrol cream was also found to be as effective as 5% acyclovir ointment (Zovirax). Resveratrol cream also effectively suppressed cold sore formation in animals with herpes simplex infection that was resistant to acyclovir. No side effects were reported.

[aquart]

15. 2000 mcg Lysine twice a day works.

Stops the developing cold sore in its tracks.

[Festivito]

31. Concur, Lysine, has worked for me for ten years.

Acyclovir was a great advance, but, Lysine remains the best thing I ever tried. When I feel it, I mega-dose, and if taken in a short time from feeling an outbreak, the skin is actually saved from peeling.

Got it as an invincible 15 year-old.

[Tangerine LaBamba]

33. When I feel that warmth starting,

I grab my tube of Zovirax, give the area a nice coat, and it stops.

Amazing how well it works for me.

[aquart]

37. Lysine. Poof!

[shanti]

48. is lysine

the primary ingredient in abreva? my son has had cold sores since age 2 (got it in daycare) and gets outbreaks which have him in bed for the first day almost every time, like having the flu. he got some prescription acyclovir, but only takes them when he thinks he'll get a sore. it would be nice for someone to cure this - he seems so miserable...:(

it pales when compared to alzheimer's tho. my grandmother suffered from it, and died shortly after diagnosis. i'm petrified that it might be hereditary...:(

[Timefortruth]

69. You might want to try elderberry syrup

It works very well for me, he might also like the taste.

[Sal Minella]

35. Yup. But it's so simple and cheap, people tend not to believe you when you tell them about lysine.

I've made converts out of several people who would listen. Daubing something on the outside of the coldsore makes less sense to me than taking something that suppresses the virus.

[dixiegrrrrl]

46. There aere certain foods which can cancel out L-Lysine.

L-Arginine is the "opposite" amino acid of L-Lysine.
I have found through experience that peanuts.nuts, peanut butter, will reduce the effectiveness
of my daily L-Lysine capsules.
It was a fascinating discovery.
Stress and nibbling nuts will increase chances of an outbreak for me.
L-Lysine stops the outbreak, lysine slave prevents the blisters.

[Sal Minella]

47. Ha! I couldn't think of "arginine" while I was writing that post! Thank you.

I learned to pop lysine after eating peanut butter and haven't had a cold sore for years now, but do go though a lot of peanut butter and a lot of lysine caps! Preventive medicine.

Arginine. That's it.

And as for stress, I am now (A) retired and (B) no longer married.
I suspect those two facts may have more to do with lack of cold sores than the lysine, actually!

[dixiegrrrrl]

49. Ahhh, yes...must stress the "stress" factor. I do tend to have more outbreaks, even mild ones, wh

As for stress here, I am retired AND finally happily married. !
Took me exactly 53 years to find "the other half".

Maybe that explains why I don't take as many Lysine caps as I used to.
( tho the election did call for an increase in them).

[Psephos]

44. Ok, I'm taking your advice and will buy some. Thanx :) n/t

[Krakowiak]

79. Yep, Lysine really does work.

[kimmerspixelated]

16. The voice of reason.

Thanks! We are lucky to be living in a time where so many good studies and reasearch has begun to prevail to prove that there are many natural cures out there. Most of the time intense nutritional therapy is what is needed to clear almost anything up. In addition,eliminating toxins will go a long way towards restoring health.

[HysteryDiagnosis]

24. Well, the resveratrol is some amazing stuff... but do read the rest

of the stuff on that page, the lysine must be mentioned there as well as others. Melissa extract is often prescribed or recommended for cold sores as well...

[hedgehog]

13. Anyone want to skip those chicken pox vaccinations any more?

It used to be that everyone was exposed to and carried the virus, but there has been speculation that it went on to cause diseases such as schizophrenia in susceptible individuals.

[kimmerspixelated]

18. Bingo!

There are many studies linking Alzheimer's to regular flu shots or innoculations. The body's immune system is always hurt by the injection of toxins. Anyone can look up the truth about the ingredients in any or all vaccines and be totally horrified. Those things have no place in the human body. Naturally, it takes it's toll eventually unless we detoxify and stay detoxified.

[Kali]

21. "There are many studies linking Alzheimer's to regular flu shots or innoculations"

please cite a few. thankyou.

[pitohui]

28. i'd be curious to see even one, alzheimer's is genetic

even this article acknowledges that virtually the entire population is already infected with herpes simplex 1 so it's still a matter of genetics if the infection leads to alzheimer's

[stray cat]

22. Antibiotics as well in your opinion?

[Bluebear]

51. "There are many studies linking Alzheimer's to regular flu shots or innoculations." - please cite 1.

[muriel_volestrangler]

61. Myth 6: Flu shots increase risk of Alzheimer’s disease

Reality: A theory linking flu shots to a greatly increased risk of Alzheimer’s disease has been proposed by a U.S. doctor whose license was suspended by the South Carolina Board of Medical Examiners. Several mainstream studies link flu shots and other vaccinations to a reduced risk of Alzheimer's disease and overall better health.

* A Nov. 27, 2001, Canadian Medical Journal report suggests older adults who were vaccinated against diphtheria or tetanus, polio, and influenza seemed to have a lower risk of developing Alzheimer’s disease than those not receiving these vaccinations. The full text of this report is posted on the journal’s Web site.

* A report in the Nov. 3, 2004, JAMA found that annual flu shots for older adults were associated with a reduced risk of death from all causes. The abstract of that report is posted on PubMed.

Alzheimer's Association

[HiFructosePronSyrup]

76. How wonderfully ironic.

Because the chicken pox virus is a close "relative" of the herpes virus.

So an variation of the chicken pox vaccine could wind up being a "vaccine" against Alzheimers.

[pitohui]

27. this isn't the same virus

this is herpes simplex 1 -- and the article says that virtually everyone is already infected with it, with about 20 to 40% of the population sometimes expressing it as a cold sore

i thought chicken pox was a varicella virus, a bit too tired to look it up right now...but i do know it's a misconception that chicken pox and smallpox are related to herpes, i once had the same misconception was corrected (i have had chicken pox and i support the vax because of the scarring i suffered as a result)

[kimmerspixelated]

20. I'm sorry, but

treating a toxin-based, or vaccine caused disease(we believe) with another vaccine, with more toxins again is kind of like adding gasoline to the fire you want to put out other than water.

[Ian David]

36. Oh, go take your unvaccinated children and live on an ilsand somewhere until you grow the fuck up.nt

[AngryAmish]

67. amen

[bananas]

26. So it's contagious?

"Don't kiss grandma"

[pitohui]

29. i don't want to call someone out

but there's a poster on this thread who has no clue what alzheimer's disease is or what the cause is

hint-- it is not caused by the flu or flu shots or vaccines for chicken pox or blah de blah de blah!

i'm sure YOU know that

[Tangerine LaBamba]

34. I'm curious

What causes it?

Do you know? Because the medical profession doesn't.

But, please, enlighten DU.

[pitohui]

40. the medical profession does know, it's well known to be genetic, esp. early onset

we know the cause of MANY forms of senility, in the case of alzheimer's there are genetic markers

in the case of pernicious anemia, the senility would be caused by lack of vit. B12 and not being dx'd in time

in the case of age related memory decline, the senility is caused by time

in some cases, the cause of the senility is a stroke or cerebral hemorrhage (argh can't spell)

the medical profession knows quite a lot, what it can do about what it knows is quite another issue

my friend w. pernicious anemia was able to stop his mental decline w. B12 injections until he got stomach cancer and it didn't seem to work any more (absorption issues?) and he became quite demented at the end

the many i've known w. alzheimer's did not have such a good result, the tools we have for that, are not good

but we do know the cause, just don't quite know where to go with the cause

hence the need for research

we're all worried and afraid, you know, no need to go tearing at each other

as the article says, almost everyone alive is infected with hsv1, yet everyone doesn't get alzheimer's...there's a genetic interaction...maybe we will have to give a vaccine to everyone (but at what age? if essentially everyone alive has the virus already, is it too late for a vaccine?) or maybe everyone with the genetic markers should be given valtrex, i dunno, but i do know it's genetic, that's a given

[Tangerine LaBamba]

41. Your information is interesting,

since not one geriatric specialist I've ever spoken with has been able to say that there is any identifiable cause for Alzheimer's.

All those words, and the answer is simply still that no one knows. Theories are nice, and a good start, but no one knows why it happens.

[Psephos]

45. We don't know exactly what causes poverty either, but we have some good ideas

Pitohui's info is both useful and current.

Senility, like cancer, is a collection of separate but related diseases, and there is no single-point cause for it. There will never be single-point cause identified for it. If you are looking for one, you are using an inadequate disease model. Research has borne good fruit so far and will bear much more in the years ahead.

[Tangerine LaBamba]

63. The cause of poverty?

Lack of money.

There. I'll bet that's been bothering you for a long time.

Glad to help.

[Psephos]

68. If you believe that then you've learned nothing from the past 40 years n/t

[Tangerine LaBamba]

70. Not lack of money?

Well, if those poor people have enough money, why are they called "poor"?

I think you're funnin' me.

[pitohui]

54. well science knows, i can't help those who have some religious reason not to read the article posted

if you have some reason not to read the article which is clearly posted what can we do?

if you have some reason not to talk to the doctors about your relative's illness what can we do?

it is well known that alzheimer's is inherited, there are genes that can be tested for and there is a search on for a cheaper test that can be done whilst we are still living and aware enough to plan for our futures -- i support this and plan to get the test when it's available because i'm at risk -- KIDDING MYSELF THAT IT AIN'T GENETIC IS UNFAIR TO MY FRIENDS AND FAMILY, GROK?

this article explains how it (possibly) interacts w. a virus that is distributed in virtually 100% of the population -- yet if you don't have the gene, the virus will just give you a cold sore or perhaps do nothing at all

READ THE DURN ARTICLE BEFORE COMMENTING

there is no serious mystery that alzheimer's is genetic, there is no serious mystery to the cause of MANY cases of senility, to pretend that there is ... counterproductive

[harpboy_ak]

59. PLEASE stop repeating this error!

You keep repeating that it's well known that AD is inherited, when that is simply NOT true. There is SOME evidence that SOME types of early onset AD MAY be inherited, but those folks are a small proportion of the AD population. You just keep repeating more hooey from your pit, when what you need to do is CHECK YOUR FACTS. What might be true for your family is not necessarily true for anyone else. Before you set yourself forth as an expert, you need to be far better informed. Right now, you're about as well informed as a majority of primary care physicians in the US, in other words, abysmally informed.

So PLEASE stop repeating your mistaken ideas as "truth".

[Tangerine LaBamba]

64. Right

The answers are in that article, right?

Theories are in that article. The word "knows" is significant here. If you know what causes something, no matter how complex it is, you are on the way to figuring out how to deal with it.

You just throw words out and think they have value. But, alas, they're meaningless if you can't make any valid point.

[alfredo]

43. So us Crohn's sufferers are at greater risk due to malabsorption of B12?

[pitohui]

55. you might be at risk for dementia caused by pernicious anemia if you can't absorb b12

i would keep an eye on it and i would never accept a dx of alzheimer's w.out getting a test for pernicious anemia, it's worth it just to make sure, because you can stop the progression of your disease by taking B12 shots if the cause is inability to absorb B12

don't know if you read all of my threads upstream, if you did, you know that eventually this man did become completely demented and raving as a result of stomach cancer but he really did last a long time and had quality of life much longer than he would have if the pernicious anemia hadn't been caught in time

he couldn't regain what he lost but he was able to stop the progression of the dementia and have some ability to reason for much longer than he would have without the B12 shots

i don't know much about crohn's disease but yeah, if it interferes w. B12 absorption i would keep a VERY sharp eye on this...if you start having "chemo fog" or "menopause fog" or whatever and you can't think clearly it can't hurt to test

you can be taught how to give yourself the B12 shots so you don't have to go to the doctor's every durn time, well worth it in my humble opinion

take care!

when you're younger apparently your body needs relatively little B12 but as you move into middle age or old age, it can be a concern, this guy was 42 when he started having symptoms

[alfredo]

58. My wife has gotten me into taking B 12 supplements. Don't know if they

help. My mom had Alzheimer's. My sister and I are waiting to see which one of us forgets the other first.

[Stuart G]

38. Sadly....600-800 Billion needed to find the direct cause and preventin..went to..

A needless war in a needless place. :(

[NoodleyAppendage]

52. Major Problem with HSV1 Theory: There are very old NORMALS with tons of amyloid plaques.

Amyloid plaque DOES NOT EQUAL Alzheimer's disease. Repeat three times, then slap media simplicity.

Actually, if anything dementia correlates with the burden of neurofibrillary tangles, not beta amyloid plaques.

J

[pitohui]

56. yeah i was thinking the same thing

but we got off on the side track of what is senility? what is alzheimer's?

[kickysnana]

60. Previous research states it is spirochetes. The plaques contain spirochtes. n/t

[Gin]

74. Geez...everything causes Alzheimer's or cancer...we should all just

throw in out cards now and get raptured.

[kickysnana]

78. How about putting the standards back into medical research that worked for centuries?

The system was changed for thte worse about 1993 and it has failed and we just need to restore it.