Save your parents....

[HysteryDiagnosis]

Many of you in here may have parents who have become diabetics, here is what you can do to help them avoid what I watched my grandfather go through.... many many years ago.


http://www.glucotize.com/images/mri_abc.rm

Diabetic complications such as neuropathy, retinopathy, and nephropathy are associated with a condition known as oxidative stress. Oxidative stress occurs as a result of cell damage caused by the proliferation of free radical molecules. Current studies suggest that the naturally occurring antioxidant a-lipoic acid is a potent oxidative stress antagonist.

Benefits

• The only controlled-release, patented a -lipoic acid
• May have the potential to reduce oxidative stress and help mitigate diabetic complications such as:
• Neuropathy
• Retinopathy
• Nephropathy
• Naturally occurring “master” antioxidant
• May aid in glucose control
• Clinically tested for safety in diabetics
• No drug interactions

Focus on Research

In the field of medicine, anecdotal evidence always precedes clinical research. To date, many diabetics (Type I & Type II) have reported the benefit of Glucotize (controlled-release a-lipoic acid) in relieving diabetic complications. Currently, clinical studies are underway to determine the exact physiological reasons why Glucotize reduces, delays and reverses oxidative stress. Two suggested studies of note are: Effects of alpha-lipoic acid on microcirculation in patients with peripheral diabetic neuropathy, E. Haak, et al; a-lipoic acid in the treatment of diabetic polyneuropathy in Germany: Current evidence from clinical trails, D. Ziegler, et al.

[LynzM]

1. I'm diabetic, and have never heard of this...

Off to do some research. I'm very skeptical of things like this, generally.

In terms of preventing Type 2 diabetes, maintaining a healthy weight level, eating well (less refined sugar, low-fat and high fiber) and exercizing regularly are some of the biggest factors. The DCCT (a 10-year study of diabetes complications in relation to glucose control) showed that the tighter your glycemic control, the lower your risk of complications.

[HysteryDiagnosis]

2. True all of that.... this will help (does help) people who cannot achieve

the type of behavior that you are describing. In some cases, it may help them to achieve those behaviors by alleviating pain, increasing energy and so forth. What are the people who have these neuropathies and retinopathies to do??

For backup, I offer this:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14984445
1: Diabet Med. 2004 Feb;21(2):114-21. Related Articles, Links

Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a meta-analysis.

Ziegler D, Nowak H, Kempler P, Vargha P, Low PA.
German Diabetes Research Institute, Leibriz Institute at the Heinrich Heine University, Dusseldorf, Germany. [e-mail]

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12423671
1: Neuropharmacology. 2002 Nov;43(6):1015-25. Related Articles, Links

Alpha-lipoic acid protects the retina against ischemia-reperfusion.

Chidlow G, Schmidt KG, Wood JP, Melena J, Osborne NN.

Nuffield Laboratory of Ophthalmology, University of Oxford, Walton Street, Oxford OX2 6AW, UK.


http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7832436
1: Ann N Y Acad Sci. 1994 Nov 17;738:257-64. Related Articles, Links

Antioxidant properties of lipoic acid and its therapeutic effects in prevention of diabetes complications and cataracts.

Packer L.

Department of Molecular and Cell Biology, University of California at Berkeley 94720.

Publication Types:

* Review
* Review, Tutorial


PMID: 7832436

[LynzM]

3. Cool, thanks for the links, I will check those out!

In terms of the other management, I meant that stuff more in terms of prevention than treatment (though it is useful for both). Particularly in people who are genetically or ethnically prone, paying attention to those things early (30s and 40s) and starting good habits then can prevent or lessen the effects later. But for those for whom it is too late, anything that helps without causing all sorts of nasty side effects is certainly welcomed! I didn't mean to imply that exercise and diet will always solve those problems, and I'm sorry if I came across that way! :)

[HysteryDiagnosis]

4. Ahhhhh, so many do come across that way and mean it.... for example

Coenzyme q10 is very protective of heart and liver tissue, glutathione, the body's own natural antioxidant is critical for persons with infectious disease, and unfortunately, it is greatly diminished in persons who start to show signs of various infectious disease, (when it starts to take them down)

This is the link to PubMed where you can research various supplements and their effects on disease. You can type in either Alpha Lipoic Acid Diabetes, or Pycnogenol Diabetes and see what turns up... you might also want to check Coenzyme q10 against diabetes as well.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi

Here is a list of papers showing the protective effects of Q10 against treatments used for a certain form of cancer....

1: Folkers K, Osterborg A, Nylander M, Morita M, Mellstedt H. Related Articles, Links
Abstract Activities of vitamin Q10 in animal models and a serious deficiency in patients with cancer.
Biochem Biophys Res Commun. 1997 May 19;234(2):296-9. Review.
PMID: 9177262
2: Iarussi D, Auricchio U, Agretto A, Murano A, Giuliano M, Casale F, Indolfi P, Iacono A. Related Articles, Links
Abstract Protective effect of coenzyme Q10 on anthracyclines cardiotoxicity: control study in children with acute lymphoblastic leukemia and non-Hodgkin lymphoma.
Mol Aspects Med. 1994;15 Suppl:s207-12.
PMID: 7752832
3: Wang SQ. Related Articles, Links
Abstract
Zhonghua Zhong Liu Za Zhi. 1991 Jan;13(1):71-3. Chinese.
PMID: 1889343
4: Tsubaki K, Horiuchi A, Kitani T, Taniguchi N, Masaoka T, Shibata H, Yonezawa T, Tsubakio T, Kawagoe H, Shinohara Y, et al. Related Articles, Links
Abstract
Gan To Kagaku Ryoho. 1984 Jul;11(7):1420-7. Japanese.
PMID: 6742867
5: Tajima M. Related Articles, Links
Abstract
Gan No Rinsho. 1984 Jul;30(9 Suppl):1211-6. Japanese.
PMID: 6471423
6: Okuma K, Furuta I, Ota K. Related Articles, Links
Abstract
Gan To Kagaku Ryoho. 1984 Mar;11(3):502-8. Japanese.
PMID: 6703724
7: Akihama T, Nakamoto Y, Shindo T, Nakayama Y, Miura A. Related Articles, Links
Abstract
Gan To Kagaku Ryoho. 1983 Oct;10(10):2125-9. Japanese.
PMID: 6354099
8: Kawase I, Niitani H, Saijo N, Sasaki H, Morita T. Related Articles, Links
Abstract Enhancing effect of coenzyme, Q10 on immunorestoration with Mycobacterium bovis BCG in tumor-bearing mice.
Gann. 1978 Aug;69(4):493-7.
PMID: 101414