A gene that causes a wide range of bacteria to become resistant to antibiotics has been found in the water supply in Delhi, with worrying implications for the rest of the globe. International travel and medical tourism have already brought the gene, known as NDM-1, to the UK. A team of scientists reported last year that they had found NDM-1 positive bacteria in a small number of patients who had visited India for kidney or bone marrow transplants, dialysis, pregnancy care or burns treatment, while others had undergone cosmetic surgery.
A paper by Timothy Walsh from Cardiff University and colleagues, published in the Lancet Infectious Diseases journal, reveals that the gene, known as NDM-1, is widespread in the water used for cooking, washing and drinking in Delhi. It will inevitably be brought into hospitals in the gut flora of patients. The potential for movement around the world is high.
NDM-1 can cause many types of bacteria – including E coli and Klebsiella pneumoniae – to become resistant to powerful antibiotics called carbapenems, which are used when other antibiotics fail to work. The team also found the gene had spread to bacteria that cause cholera and dysentery. "Worryingly, dysentery caused by this particular isolate is currently untreatable," said Mark Toleman, one of the authors.
The findings are published on World Health Day, which this year is dedicated to preserving the healing powers of the antibiotics we still have. The World Health Organisation warns that more than 25,000 people die every year in the EU alone from infections caused by antibiotic-resistant bacteria.
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http://www.guardian.co.uk/world/2011/apr/07/superbug-gene-rife-delhi-water