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Aloe Vera Gel effective in Oral Lichen Planus

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Celebration Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Feb-23-08 04:39 PM
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Aloe Vera Gel effective in Oral Lichen Planus
http://www.ncbi.nlm.nih.gov/pubmed/18093246?ordinalpos=16&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

Background Oral lichen planus (OLP) is a chronic inflammatory disease that can be painful especially in the atrophic and erosive forms. Several therapies have been tried, with varying results. There is one case report in which aloe vera (AV) was used successfully in the treatment of lichen planus. Objectives To compare the efficacy of AV and placebo in the topical management of OLP. Methods A randomized, double-blind, placebo-controlled trial was designed. Fifty-four patients were randomized into two groups to receive AV gel or placebo for 8 weeks. Results Fifty-four consecutive patients (34 women and 20 men) participated in the study. We found erosive and ulcerative lesions in 83% and 17%, respectively. The most common site of OLP was the lower lip. Twenty-two of 27 patients treated with AV (81%) had a good response after 8 weeks of treatment, while one of 27 placebo-treated patients (4%) had a similar response (P < 0.001). Furthermore, two patients treated with AV (7%) had a complete clinical remission. Burning pain completely disappeared in nine patients treated with AV (33%) and in one treated with placebo (4%) (P = 0.005). Symptomatology improved by at least 50% (good response) in 17 patients treated with AV (63%) and in two treated with placebo (7%) (P < 0.001). No serious side-effects were found in both groups. Conclusions AV gel is statistically significantly more effective than placebo in inducing clinical and symptomatological improvement of OLP. Therefore, AV gel can be considered a safe alternative treatment for patients with OLP.

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Jane Austin Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Feb-23-08 05:07 PM
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1. There are some great Aloe Vera products called Aloe80
that I've been using.

They have shampoo, facial cleanser, gel, hand soap, conditioner, facial toner - all kinds of things with 80% Aloe.

For me they calm down all sorts of skin issues.

Also, Kiss My Face or Jason has an Aloe Veral mouthwash that I like.
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