Hereditary Heart Disease, Dr. Sinatra MD, cardiologist.

[HysteryDiagnosis]

This is as real and as truthful as it gets IMHO. I have been following this topic and the results of supplementation or dietary modification for quite a long time. We just lost a family member to sudden cardiac arrest. I will be giving this book out for xmas this year.

http://www.amazon.com/dp/1591201586/ref=pe_606_8658510_pe_ar_t1



http://ecx.images-amazon.com/images/I/512M4X76D9L._BO2,204,203,200_PIsitb-dp-500-arrow,TopRight,45,-64_OU01_AA240_SH20_.jpg

Unfavorable review reversed:

5.0 out of 5 stars vital information for medical providers, November 16, 2007
By Ira M. Edwards - See all my reviews
(REAL NAME)
I gave an unfavorable review a few days ago, thinking of cardiac patients who probably won't get far in a book that is not well written. But the information Dr. Sinatra presents is so important, and so neglected by medical doctors, that now I deleted my former review, and now rate it five stars. Many cardiac patients will be much healthier if their doctors understand the importance of magnesium, enzyme coQ10, carnitine and ribose.
I am the author of HONEST NUTRITION and a book in progress about chronic diseases. I have learned much from Dr. Sinatra and his great newsletter.


Great review:

By N. Tippett - See all my reviews
(REAL NAME)
I ordered Dr. Sinatra's other heart book "Heart Sense for Women" for my mother as a Mother's Day gift 5 years ago. The information she gleaned from that book has transformed her. Now both my parents are taking heart health supplements and doing great (they are in their 80's). They showed this latest book to their cardiologist (he is the head cardiologist at Johns Hopkins)who strongly recommended they continue on the supplements as he takes them as well. They look and feel great. I have since started supplementing myself since heart disease is hereditary. I would highly recommend this book to anyone concerned about their heart health. It's an eye opener.


Another great review:

By Tinkerbell (Miami) - See all my reviews
Dr Sinatra has written a great book ! It has lots of information that we can use.
He tells us that blood flow to the heart increases 38 % in people taking CoQ10, also this same people will have a 9 % improvement in the heart functional capacity. Foods rich in CoQ10 are Oily fish with high levels of Omega-3 (salmon ), organ meats and whole grains. (Just in case you decide to go the food way ). He also mentions that the best CoQ10 is made with the Bio-Solv technology and is called Q-Gel. Just Google it.

He says that the "Twin Pillars of Healing" are CoQ10 and L-Carnitine, they both enhance energy at a cellular level.
CoQ10 sparks energy in the cells and L-Carnitine is necessary to bring the fuel into the heart cells to be burned for energy, and the heart needs constant energy to pump properly.

He also talks about other very important nutrients like Alpha Lipoic Acid (ALA), N-Acetylcysteine (NAC), OPC's (grape seed and Pycnogenol ), etc.

Psssss......Let me tell you a secret.....All of my MD. friends take CoQ10.

Buy this book, it's so good ! has so much detail. Also "Heart Sense for Women" by Dr, Sinatra , is excellent.


All pretty much great reviews at this link ---> http://www.amazon.com/review/product/1591201586/ref=cm_cr_dp_synop?%5Fencoding=UTF8&sortBy=bySubmissionDateDescending#R93B3X43GSJO3

[medeak]

1. nothing new here to me

btw..the best place to get Q-gel CoQ10 is epic health online..most potent

[HysteryDiagnosis]

2. You're one of the lucky ones, wait until the sweepers come to

pick at this as if it were written by a 3rd grader.



34 of 34 people found the following review helpful:
5.0 out of 5 stars This works for me, August 28, 2005
By E. Lusignan "edlusign1" (MA United States) - See all my reviews
(REAL NAME)
I'm a person with severe heart problems I have been using his recommendations for 5 years and it has made a big difference to me. In this book he adds D Ribose to the treatment. This last material is one that I had never heard off. When I added it to the rest of things he recommends it really made a very big difference to me in reducing most all of my symtoms. If you have heart dissease you owe
it to yourself to read this book.

[trotsky]

6. "The sweepers," eh?

Yeah, someone's definitely ACTING like a 3rd grader.

The bottom line is, people should be suspicious of ANYONE pushing a miracle cure or treatment. NO ONE has all the answers, and anyone saying otherwise is DUPING you for money.

Most people have adequate CoQ10 from their diet, or by their own bodies making it themselves. No study has ever shown it to prevent or cure any condition. The ONLY study that has indicated it may be beneficial is in the case of patients who already have severe heart disease. It's also expensive, and considering how viciously "big pharma" is bashed in here because of its profit motive, you'd think CoQ10 would be viewed with a similarly skeptical eye. But no, it's all or none around here. Big pharma = evil, "supplements" = good.

[HysteryDiagnosis]

7. No study has ever shown it to prevent or cure any condition.

I beg to differ. Coenzyme Q10 can treat the disease caused by statin drugs (commonly called myopathy)


1: Am J Cardiol. 2007 May 15;99(10):1409-12. Epub 2007 Apr 3.Click here to read Links

Comment in:
Am J Cardiol. 2007 Nov 1;100(9):1497-8.

Effect of coenzyme q10 on myopathic symptoms in patients treated with statins.
Caso G, Kelly P, McNurlan MA, Lawson WE.

Department of Surgery, Division of Cardiology, Stony Brook University, Stony Brook, NY, USA. [e-mail]

Treatment of hypercholesterolemia with statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) is effective in the primary and secondary prevention of cardiovascular disease. However, statin use is often associated with a variety of muscle-related symptoms or myopathies. Myopathy may be related in part to statin inhibition of the endogenous synthesis of coenzyme Q10, an essential cofactor for mitochondrial energy production. The aim of this study is to determine whether coenzyme Q10 supplementation would reduce the degree of muscle pain associated with statin treatment.

Patients with myopathic symptoms were randomly assigned in a double-blinded protocol to treatment with coenzyme Q10 (100 mg/day, n = 18) or vitamin E (400 IU/day, n = 14) for 30 days. Muscle pain and pain interference with daily activities were assessed before and after treatment. After a 30-day intervention, pain severity decreased by 40% (p <0.001) and pain interference with daily activities decreased by 38% (p <0.02) in the group treated with coenzyme Q10. In contrast, no changes in pain severity (+9%, p = NS) or pain interference with daily activities (-11%, p = NS) was observed in the group treated with vitamin E. In conclusion, results suggest that coenzyme Q10 supplementation may decrease muscle pain associated with statin treatment. Thus, coenzyme Q10 supplementation may offer an alternative to stopping treatment with these vital drugs.

PMID: 17493470

[trotsky]

9. LOL

"may decrease muscle pain"

In other words, the one study you have indicates it may help a symptom that has NOTHING AT ALL to do with your OP.
:rofl:

[HysteryDiagnosis]

10. How many people have you healed in your time sonny?? What I

indicated was that your life saving drugs kill people. On the other hand, the supplements Dr. Sinatra heals people oftentimes without drugs. If you can't deal with it, ignore it.

[trotsky]

12. "My" life saving drugs?

It's too bad that you're so caught up in the black-vs-white mentality that you can't imagine anyone would disagree with you unless they're an agent of big pharma.

But guess what? Big pharma drugs have SAVED millions of people. I know that the all-or-none thinking you are stuck in can't acknowledge that part of the equation, but the fact is, they do save lives, extend lives, and improve the quality of life for millions. Are they perfect? Nope. Good thing neither I, nor anyone else in the Health Scare Lounge has ever said so! Dr. Sinatra is just the latest know-it-all peddling a wonder cure, and you're falling for him hook line and sinker. He's making LOTS of money - which is the very reason you distrust big pharma! But you'll never see why your behavior is inconsistent - you've got your good-vs-evil Republican-style thinking fully engaged and nothing's going to convince you otherwise. Good luck.

[HysteryDiagnosis]

11. Diabetes, I'm sure these medical professionals are doing this

Sort of work because you say there is nothing to it. What a joke.

Coenzyme Q(10) improves endothelial dysfunction of the brachial artery in Type II diabetes mellitus.
Watts GF, Playford DA, Croft KD, Ward NC, Mori TA, Burke V.

Department of Medicine, University of Western Australia, Royal Perth Hospital, Perth, Australia. [e-mail]

AIM/HYPOTHESIS: We assessed whether dietary supplementation with coenzyme Q(10) improves endothelial function of the brachial artery in patients with Type II (non-insulin-dependent) diabetes mellitus and dyslipidaemia. METHODS: A total of 40 patients with Type II diabetes and dyslipidaemia were randomized to receive 200 mg of coenzyme Q(10) or placebo orally for 12 weeks. Endothelium-dependent and independent function of the brachial artery was measured as flow-mediated dilatation and glyceryl-trinitrate-mediated dilatation, respectively. A computerized system was used to quantitate vessel diameter changes before and after intervention.

Arterial function was compared with 18 non-diabetic subjects. Oxidative stress was assessed by measuring plasma F(2)-isoprostane concentrations, and plasma antioxidant status by oxygen radical absorbance capacity. RESULTS: The diabetic patients had impaired flow-mediated dilation <3.8 % (SEM 0.5) vs 6.4 % (SEM 1.0), p = 0.016>, but preserved glyceryl-trinitrate-mediated dilation, of the brachial artery compared with non-diabetic subjects. Flow-mediated dilation of the brachial artery increased by 1.6 % (SEM 0.3) with coenzyme Q(10) and decreased by -0.4 % (SEM 0.5) with placebo (p = 0.005); there were no group differences in the changes in pre-stimulatory arterial diameter, post-ischaemic hyperaemia or glyceryl-trinitrate-mediated dilation response. Coenzyme Q(10) treatment resulted in a threefold increase in plasma coenzyme Q(10) (p < 0.001) but did not alter plasma F(2)-isoprostanes, oxygen radical absorbance capacity, lipid concentrations, glycaemic control or blood pressure.

CONCLUSION/INTERPRETATION: Coenzyme Q(10) supplementation improves endothelial function of conduit arteries of the peripheral circulation in dyslipidaemic patients with Type II diabetes. The mechanism could involve increased endothelial release and/or activity of nitric oxide due to improvement in vascular oxidative stress, an effect that might not be reflected by changes in plasma F(2)-isoprostane concentrations.

PMID: 11914748

The effect of coenzyme Q10 administration on metabolic control in patients with type 2 diabetes mellitus.
Eriksson JG, Forsén TJ, Mortensen SA, Rohde M.

National Public Health Institute, Department of Epidemiology and Health Promotion, Helsinki, Finland. [e-mail]

A possible relationship between the pathogenesis of type 2 diabetes and coenzyme Q10 (CoQ10) deficiency has been proposed. The aim of this study was to assess the effect of CoQ10 on metabolic control in 23 type 2 diabetic patients in a randomized, placebo-controlled trial. Treatment with CoQ10 100 mg bid caused a more than 3-fold rise in serum CoQ10 concentration (p < 0.001). No correlation was observed between serum CoQ10 concentration and metabolic control. No significant changes in metabolic parameters were observed during CoQ10 supplementation. The treatment was well tolerated and did not interfere with glycemic control, therefore CoQ10 may be used as adjunctive therapy in patients with associated cardiovascular diseases.

PMID: 10416046

[trotsky]

13. Totally supports what I already said.

The only confirmed benefit from CoQ10 so far has been in patients WITH heart disease. Your huckster is trying to sell a cure-all/preventative, and there is no evidence to date that CoQ10 is such a thing. Keep attacking me if you wish, but until you can provide some kind of evidence supporting your position you'll just look more bitter and foolish.

[grasswire]

14. I do not know where these vicious people come from...

...and I'm sorry they have attacked you for posting useful information. It has happened to me as well, previously. They call certain doctors "hucksters" and defend big pharma?

Crazy.

[trotsky]

16. Why can't you just speak to me instead of playing this silly game?

When a doctor is saying things that aren't supported by research, he's cheating people of their money. That, to me, is a huckster. Sorry if you see things differently.

[HysteryDiagnosis]

17. They come from the sea of unknowingness. They should stay

there so that truth and knowledge can spread as it should. Thanks for the thumbs up. :)

[trotsky]

18. How childish.

Anything that can't withstand the "sea" of TRUTH isn't worth believing. Your doctor hero is making unsupported claims and swindling people of their money. I care about that. You obviously don't, because he's saying things you want to hear, and in your black-and-white world, that's just swell.

Let me know when you're out of junior high and can discuss the issue rather than toss juvenile insults.

[HysteryDiagnosis]

19. What? This doctor is swindling people by telling them about

things that "may and often do" improve a person's quality of life. Rubbish. You have come this .. close to being on ignore. I have no one on ignore but certainly you will be the first. If you are unawares as to the therapeutic benefits of Co Q10, L-carnitine, D-Ribose, Hawthorn, Omega threes and the like, AND if you don't want to know about them sign off. If you do, buy the book, eat some crow and then see how things look to you AFTER you have read the FACTS.

[trotsky]

20. You can ignore the truth if you wish.

Clearly you've made up your mind, and you have to view things in such black-and-white terms that you simply refuse to listen to real evidence, instead picking and choosing just the data you want to believe.

I'm sorry, but science and medicine don't work that way.

Studies simply don't support the claims your latest hero is saying. Feel free to ignore me if you can't stand THAT fact. Follow through on your threat - ignore me if you can. But I'll be here, countering every time you post opinion as fact and spread medical misinformation that could harm people or steal their money for false hope.

[Fire_Medic_Dave]

21. The risk of statin related myopathy is extremely low.

The patients complaining of muscle pain associated with statin use is low 1 in 10,000 patients. For some people, change in diet, exercise and taking supplements help tremendously. For others with familial hypercholesterolemia, statins or similar drugs are needed.

David

[Celebration]

22. it depends on the profile of the person

Beware if you are someone who exercises a lot!!

http://www.drmirkin.com/heart/statins_muscle_pain.html

Some patients with high cholesterol levels are afraid to take statins because off fear of developing side effects such as muscle pain. A study from Scripps Mercy Hospital in San Diego reviews the latest data on side effects of statins (The American Journal of Medicine, May 2006). This review found that statin- induced muscle damage is more common in Asians, people who exercise, have had recent surgery, have kidney, liver or thyroid disease, or have high triglycerides. The incidence of muscle pain and damage from statins is extremely low in non- exercisers, three to ten percent in those who exercise, and very high in competitive athletes.

Most athletes refuse to take statin drugs because they train by taking a hard workout that damages their muscles. Then they must take easy workouts until the soreness disappears and muscles heal. When statins prevent this muscle healing, the athlete must train at reduced intensity for a much longer period of time. Brand names of statins include: Altoprev, Crestor, Lipitor, Mevacor, Pravachol and Zocor.

[Fire_Medic_Dave]

23. I don't take statins I take fibrates.

I haven't experienced any side effects from them and my triglycerides and cholesterol have improved.

David

[grasswire]

4. what the drug stores don't tell people....

...is that all that CoQ10 they are selling is hard to absorb. Sinatra recommends finding water soluble product. And I haven't seen that yet in a local drug store.

[Warpy]

8. You can probably order it online

and some health foods outlets with large vitamin counters probably stock it.

However, the oil soluble form is absorbed, just not as completely. People who produce the oil soluble for in capsules compensate for bumping the dose up.

[medeak]

15. http://www.epic4health.com/

was directed to this site by parkinson's association as parkinson's pts recommended to take 1200 mg per day.. this is the most potent and best absorbed maker I was told by not just Parkinson's assoc...but several docs.

They're great re service as well.

edited to say...did my own research and started husband on it 5 yrs ago..motion disorder specialist called last year and said new findings by FDA and AMA recommended 1200 mg. I didn't say anything that we had started it years ago...but was glad conventional medicine had caught up.

[grasswire]

3. much of his info is available at his web site

His cardiac recommendations are there. I've been working toward the goal of taking the supplements he recommends.

See his web site for LOTS of info.

And a note to mods: Do NOT lock this thread, I beg you. This is advice from a prominent physician, not we amateurs. Everyone who reads this should check with their physician about supplements, obviously.

Dr. Sinatra's top 15 tips for a healthy heart:

1. Modified Medterranean diet.

2. Raise your fitness level.

3. Join a cardiac rehab program. (Most people can't afford to do that.)

4. Reduce your stress.

5. Multi-vitamin with carotenoidfs, flavonoids, vitamins C,E and B, selenium and cardiac-supporting herbs.

6. Coenzyme Q10. Water-soluble is best if you can find it.

7. L-carnitine

8. Magnesium and calcium.

9. Fish oil

10 Stop smoking.

11. L-arginine, an amino acid.

12. Taurine for CHF

13. Nattokinase

14. If your response to CoQ10 is insufficient and you have CHF, add hawthorn berry.

15. Alcohol: limit it!

Then here is his expanded list of supplements:

Vitamin E
Tocotrienols
Carotenoids
Lutein
Magnesium
B-Vitamins and Folic Acid
Vitamin C
CoQ10
L-Carnitine
Alpha Lipoic Acid
N-acetylcysteine
Oligomeric Proanthocyanidins
L-arginine
Good multi-vitamin.

I urge you all to explore his web site. http://www.drsinatra.com

[HysteryDiagnosis]

5. Read my new and improved sig line and thanks for the positive

input. :)