Is Vitamin D Deficiency Linked To Alzheimer's Disease And Vascular Dementia?

[Celebration]

http://www.sciencedaily.com/releases/2009/05/090526140747.htm

There are several risk factors for the development of Alzheimer's disease and vascular dementia. Based on an increasing number of studies linking these risk factors with Vitamin D deficiency, an article in the current issue of the Journal of Alzheimer's Disease (May 2009) by William B. Grant, PhD of the Sunlight, Nutrition, and Health Research Center (SUNARC) suggests that further investigation of possible direct or indirect linkages between Vitamin D and these dementias is needed.


Low serum levels of 25-hydroxyvitamin D <25(OH)D> have been associated with increased risk for cardiovascular diseases, diabetes mellitus, depression, dental caries, osteoporosis, and periodontal disease, all of which are either considered risk factors for dementia or have preceded incidence of dementia. In 2008, a number of studies reported that those with higher serum 25(OH)D levels had greatly reduced risk of incidence or death from cardiovascular diseases.

Several studies have correlated tooth loss with development of cognitive impairment and Alzheimer's disease or vascular dementia. There are two primary ways that people lose teeth: dental caries and periodontal disease. Both conditions are linked to low vitamin D levels, with induction of human cathelicidin by 1,25-dihydroxyvitamin D being the mechanism.

There is also laboratory evidence for the role of vitamin D in neuroprotection and reducing inflammation, and ample biological evidence to suggest an important role for vitamin D in brain development and function.

Given these supportive lines of evidence, Dr. Grant suggests that studies of incidence of dementia with respect to prediagnostic serum 25(OH)D or vitamin D supplementation are warranted. In addition, since the elderly are generally vitamin D deficient and since vitamin D has so many health benefits, those over the age of 60 years should consider having their serum 25(OH)D tested, looking for a level of at least 30 ng/mL but preferably over 40 ng/mL, and supplementing with 1000-2000 IU/day of vitamin D3 or increased time in the sun spring, summer, and fall if below those values.

[Why Syzygy]

1. +4

[Sanity Claws]

2. + infinity

I just felt competitive but didn't want to get off my butt and really do something.

[NYC_SKP]

7. + infinity and two snaps up!

[glitch]

3. Anti-flu, anti-cancer and now anti-alzheimers? K & R

time to take some vitamin d

[FourScore]

4. I believe that I once read that Alzheimer's could be what is called a "slow virus"

much like CJD (the human varient of mad cow) and other degenerative brain diseases.
If so, this article makes a lot of sense. Vitamin D is known for it's powerful anti-viral properties. (Remember that when flu season starts. It could help you against swine flu.)

Good post. bookmarking. Recommending.

[bettyellen]

5. i forgot about that - you have an interesting take on it.

it;s confusing. i mea, it seems like all deseases are somehow living things- parasites or germs and viruses. for me, the lines seem pretty blurred.

[kevinthomas]

6. fantastic information

it is great to know that how important is vitamin D in our body.
fantastic information.

[tiptoe]

8. k & r nt

[D-Lee]

9. go to this link for the Vitamin D Council for lots of other info

www.vitamindcouncil.org/

the newsletter is very informative