You have heard of tissue expanders to increase the surface area of skin to be transplanted to areas where it is needed. Here is a technique for creating heart muscle by growing it in a biodegradable "scaffold" was seeded with immature cells taken from the hearts of newborn rats. For 48 hours, this was exposed to a cocktail of growth-promoting chemicals in the laboratory. Then it was transplanted into a rat's abdomen where it developed a network of blood vessels and muscle fibres. In human patients, grafts would probably be seeded with cells derived from stem cells.
'Patch' able to mend a broken heartA "patch" has been made from heart muscle that can be used to fix scarring left over from a heart attack.
Writing in the journal PNAS, the scientists describe how the technique strengthened the hearts of rats that had suffered heart attacks.
The "patch" was grown in abdominal tissue first, then transplanted to damaged areas of the heart.
This experiment is the first to show that such patches can actually improve the health of a heart after it has been damaged.
Broken hearts mend with 'patch'