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Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsThis new antibody can stop all COVID-19 strains, including new variants, experts say
Last edited Mon Aug 30, 2021, 02:54 AM - Edit history (1)
A new antibody theory can reportedly neutralize all COVID-19 strains and coronavirus, paving the way for stopping COVID-19https://www.deseret.com/coronavirus/2021/8/27/22643254/antibody-stops-covid-19-coronavirus-variants-delta-lambda
This undated electron microscope image made available by the U.S. National Institutes of Health in February 2020 shows the virus that causes COVID-19. NIAID-RML via Associated Press
A team of researchers may have found an antibody that can neutralize all known novel coronavirus strains, including the developing variants. GlaxoSmithKline and Vir Biotechnology recently conducted a huge collaborative study by scientists and developed a new antibody therapy, called Sotrovimab. During the project, they discovered a new natural antibody that has remarkable breadth and efficacy, according to the Berkeley Lab.
The scientists reportedly discovered a new antibody, called S309, which neutralizes all known SARS-CoV-2 strains including newly emerged mutants that can now escape from previous antibody therapies as well as the closely related original SARS-CoV virus, according to a press release from the Berkeley Lab. Structural biologist Jay Nix, who was involved with the project, said the antibody can potentially stop all coronaviruses similar to COVID-19.
The researchers want to do more tests with the antibodies using hamsters. They hope to give it prophylactically but its unclear when that would be. And, due to the unique binding site on mutation-resistant part of the virus, it may well be more difficult for a new strain to escape, he said in a release from Berkeley Lab. The information about the antibody was published in the journal Nature.
A similar study recently published in the New England Journal of Medicine said that researchers found high-level, broad-spectrum antibodies in blood samples from SARS outbreak survivors in 2003, as I explained for the Deseret News. Back in 2020, scientists at the University of Pittsburgh School of Medicine discovered the smallest biological molecule that completely and specifically neutralizes the novel coronavirus, too, as I wrote for the Deseret News. The scientists developed a drug, called Ab8, that would be used as a preventative measure against COVID-19, according to Fox News.
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littlemissmartypants
(22,656 posts)LW1977
(1,234 posts)Celerity
(43,349 posts)https://www.business-standard.com/article/current-affairs/south-africa-detects-new-variant-of-interest-of-covid-19-c-1-2-121082900752_1.html
South Africa has identified a potential variant of interest (VOI) of Covid-19 that is assigned to the PANGO lineage C.1.2. C.1.2 was first identified in May 2021 during the third wave of Covid in the country, said researchers from the country's National Institute for Communicable Diseases (NICD) and the KwaZulu-Natal Research Innovation and Sequencing Platform. It has since been detected across the majority of the provinces in South Africa and in seven other countries spanning Africa, Europe, Asia and Oceania, the researchers reported in the study that is yet to be peer-reviewed and is posted on pre-print server medRxiv.
The variant has evolved from C.1, one of the lineages that dominated the first wave of SARS-CoV-2 infections in South Africa and was last detected in January 2021. C.1.2 is "associated with increased transmissibility and reduced neutralisation sensitivity," wrote the team, including Cathrine Scheepers, from NICD, in the abstract. Compared to C.1, the new variant has "mutated substantially" and is more mutations away from the original virus detected in Wuhan than any other Variant of Concern (VOC) or VOI detected so far worldwide.
Further, the study also found consistent increases in the number of C.1.2 genomes in South Africa on a monthly basis, rising from 0.2 per cent in May to 1.6 per cent in June and 2.0 per cent in July. The researchers stated that it is similar to the increases seen in Beta and Delta in South Africa during early detection. As of August 20, 2021, 80 sequences that match the C.1.2 lineage have been listed on the open-access database GISAID (Global Initiative on Sharing Avian Influenza Data). More study is needed "to determine the functional impact of these mutations, which likely include neutralising antibody escape, and to investigate whether it confers advantage over the Delta variant," Scheepers said.
Meanwhile, India has also reported the presence of a new sub-lineage AY.12 of the Delta variant of Covid, that was recently classified in Israel. A recent report by the Indian SARS-CoV-2 Genomics Consortium (INSACOG), many cases in India that were earlier classified as Delta, are now being reclassified as AY.12.
friend of m and j
(220 posts)CREDIBLE IF IT WERE NOT BEING ANNOUNCED BY FOX NEWS.
Celerity
(43,349 posts)Pittsburgh School of Medicine were Fox News.
Who knew!
( not sure about that Nature dude. sounds a bit hipstir to me )
mahina
(17,652 posts)Why the irk?
Celerity
(43,349 posts)and the short Fox article at the last link was a hard news piece, with zero editorial. I see Murdoch's NY Post (every bit as RW as Fox News) used as the actual OP articles (and often slanted ones at that) here all the time and nary a boo is heard.
But dog forbid, one link in a non Fox OP, and to a hard news article (zero editorial slant) and all of sudden the entire OP is spun up as 'Fox News' and therefore somehow invalid. That is just bollocks. I may be young but I didn't just just fall off the banana lorry.
That poster was trying to toss FUD into my OP by both misrepresentation and 🍒 picking.
mahina
(17,652 posts)Curious. Ill have another look.
OhioChick
(23,218 posts)PSPS
(13,595 posts)NJCher
(35,667 posts)To hear something like this is in the pipeline!
Fiendish Thingy
(15,607 posts)Hopeful, but inconclusive, news at this point.
tanyev
(42,554 posts)With just a soupcon of the blood of Jesus.
ananda
(28,859 posts)!!!
MineralMan
(146,298 posts)much less in humans. We're far away from it being available to treat Covid-19 patients. Very early evidence that may or may not end up being useful.
Response to MineralMan (Reply #14)
Celerity This message was self-deleted by its author.
Celerity
(43,349 posts)much less in humans
Is simply untrue.
It has been in human trials for months and months , and the already FDA granted an EUA back in May.
https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-additional-monoclonal-antibody-treatment-covid-19
For Immediate Release:
May 26, 2021
Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the investigational monoclonal antibody therapy sotrovimab for the treatment of mild-to-moderate COVID-19 in adults and pediatric patients (12 years of age and older weighing at least 40 kilograms [about 88 pounds]) with positive results of direct SARS-CoV-2 viral testing and who are at high risk for progression to severe COVID-19, including hospitalization or death. This includes, for example, individuals who are 65 years of age and older or individuals who have certain medical conditions.