CDC gives three-month window of immunity after COVID-19 infection

[brooklynite]

Source: The Hill

A person who has recovered from COVID-19 will likely be safe from reinfection for three months, according to updated guidance from the Centers for Disease Control and Prevention (CDC).

The information marks the first acknowledgement of a defined immunity period for people who have recovered from a COVID-19 infection.

Prior research has shown antibodies from recovered patients will fade over the course of a few months, but federal scientists had not previously said what that means for immunity.

The CDC previously recommended that someone recovered from a COVID-19 infection doesn't need to be tested again for three months so long as that person is asymptomatic, but made clear that any correlation to immunity was still unknown.

Read more: https://thehill.com/policy/healthcare/512090-cdc-gives-three-month-window-of-immunity-after-covid-infection

[Tetrachloride]

1. Dr. Fauci is not likely to agree. MOREOVER, just because one might be

immune does not mean they are not a carrier.

Since the CDC has been compromised and subverted by Trump, I will wait for Dr. Fauci, the World Health Organization and a lettuce and tomato sandwich.

[yaesu]

2. pretty much like the common cold, another coronavirus. nt

[Celerity]

3. approx. 15% of common colds are caused by coronaviruses, rihnoviruses are the most common cause

https://en.wikipedia.org/wiki/Common_cold#Viruses

The common cold is a viral infection of the upper respiratory tract. The most commonly implicated virus is a rhinovirus (30–80%), a type of picornavirus with 99 known serotypes. Other commonly implicated viruses include human coronaviruses (? 15%), influenza viruses (10–15%), adenoviruses (5%), human respiratory syncytial virus (orthopneumovirus), enteroviruses other than rhinoviruses, human parainfluenza viruses, and human metapneumovirus. Frequently more than one virus is present. In total, more than 200 viral types are associated with colds.

[yaesu]

5. it would be interesting to find out if getting the common cold coronavirus helps with immunity

cross-immunity as some researchers claim. Also, some mild coronavirus T-cell immunity seems to last almost a year in some cases.

[Celerity]

8. Immunity to COVID-19 is probably higher than tests have shown

New research from Karolinska Institutet and Karolinska University Hospital shows that many people with mild or asymptomatic COVID-19 demonstrate so-called T-cell-mediated immunity to the new coronavirus, even if they have not tested positively for antibodies. According to the researchers, this means that public immunity is probably higher than antibody tests suggest. The article is freely available on the bioRxiv server and has been submitted for publication in a scientific journal.

https://news.ki.se/immunity-to-covid-19-is-probably-higher-than-tests-have-shown

“T cells are a type of white blood cells that are specialised in recognising virus-infected cells, and are an essential part of the immune system,” says Marcus Buggert, assistant professor at the Center for Infectious Medicine, Karolinska Institutet, and one of the paper’s main authors. “Advanced analyses have now enabled us to map in detail the T-cell response during and after a COVID-19 infection. Our results indicate that roughly twice as many people have developed T-cell immunity compared with those who we can detect antibodies in.” In the present study, the researchers performed immunological analyses of samples from over 200 people, many of whom had mild or no symptoms of COVID-19. The study included inpatients at Karolinska University Hospital and other patients and their exposed asymptomatic family members who returned to Stockholm after holidaying in the Alps in March. Healthy blood donors who gave blood during 2020 and 2019 (control group) were also included.

T-cell immunity in asymptomatic individuals

Consultant Soo Aleman and her colleagues at Karolinska University Hospital’s infection clinic have monitored and tested patients and their families since the disease period. “One interesting observation was that it wasn’t just individuals with verified COVID-19 who showed T-cell immunity but also many of their exposed asymptomatic family members,” says Soo Aleman. “Moreover, roughly 30 per cent of the blood donors who’d given blood in May 2020 had COVID-19-specific T cells, a figure that’s much higher than previous antibody tests have shown.” The T-cell response was consistent with measurements taken after vaccination with approved vaccines for other viruses. Patients with severe COVID-19 often developed a strong T-cell response and an antibody response; in those with milder symptoms it was not always possible to detect an antibody response, but despite this many still showed a marked T-cell response.

Very good news from a public health perspective

“Our results indicate that public immunity to COVID-19 is probably significantly higher than antibody tests have suggested,” says Professor Hans-Gustaf Ljunggren at the Center for Infectious Medicine, Karolinska Institutet, and co-senior author. “If this is the case, it is of course very good news from a public health perspective.” T-cell analyses are more complicated to perform than antibody tests and at present are therefore only done in specialised laboratories, such as that at the Center for Infectious Medicine at Karolinska Institutet. “Larger and more longitudinal studies must now be done on both T cells and antibodies to understand how long-lasting the immunity is and how these different components of COVID-19 immunity are related,” says Marcus Buggert.

The results are so new that they have not yet undergone peer review ahead of publication in a scientific journal. Pending such review, the article has been published on a preprint server, bioRxiv (see box). The study was financed by the Knut and Alice Wallenberg Foundation, Nordstjernan AB, the Swedish Research Council, Karolinska Institutet, the Swedish Society for Medical Research, the Jeansson Foundations, the Åke Wiberg Foundation, the Swedish Society of Medicine, the Swedish Cancer Society, the Swedish Childhood Cancer Foundation, the Magnus Bergvall Foundation, the Hedlund Foundation, the Lars Hierta Foundation, the Swedish Physicians against AIDS foundation, the Jonas Söderquist Foundation, the Clas Groschinsky Memorial Foundation, and the Wellcome Trust. The authors report no conflicts of interest or patents associated with the results of the study.

snip


Publication

https://doi.org/10.1101/2020.06.29.174888

“Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19”

Takuya Sekine, André Perez-Potti, Olga Rivera-Ballesteros, Jean-Baptiste Gorin, Annika Olsson, Habiba Kamal, Sian Llewellyn-Lacey, David Wulliman, Tobias Kamann, Gordana Bogdanovic, Sandra Muschiol, Elin Folkesson, Olav Rooyackers, Lars I. Eriksson, Anders Sönnerborg, Tobias Allander, Jan Albert, Morten Nielsen, Kristoffer Strålin, Sara Gredmark-Russ, Niklas K. Björkström, Johan K. Sandberg, David A. Price, Hans-Gustaf Ljunggren, Soo Aleman, Marcus Buggert, Karolinska COVID-19 Study Group.
bioRxiv, online 29 June 2020, doi: 10.1101/2020.06.29.174888

[Igel]

7. Except it's a statement of a minimum considered likely to be true.

Without an implied termination of immunity.

Paraphrase it as, "We're pretty certain that for the three months after recovery--unless you become symptomatic again--you won't be infectious. After that, we don't know." Versus "We're pretty certain that for the three months after recovery .... After that, you could easily become infected again and be contagious."

It takes a week or two to produce the guidance. That means the time that they started their count from is 5/5 or so. If it takes 3-4 weeks for recovery, that pushes it back to early-ish April. Which is about the time that there were significant numbers of domestic cases for study, as well as European cases. Everything before that relies on data that aren't very transparent or which are few in number.

[underpants]

4. Good news but this will be twisted probably into herd immunity BS

Just saying

[regnaD kciN]

9. I don't see how this is "good news"...

It would seem to suggest that any vaccine, should it come, would only be effective for three months.

It suggests that COVID is going to remain a lethal threat to all of us...well, forever.

[iluvtennis]

6. Until I hear it from Dr Fauci, I'm skeptical. nt

[catrose]

10. Me too. I'd cut that figure in half, at least, just as a working number.