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Related: About this forumUp to 7 years of hormone therapy is safe for postmenopausal women, new data show
Source: Los Angeles Times
Up to 7 years of hormone therapy is safe for postmenopausal women, new data show
By Melissa Healy
SEPTEMBER 12, 2017, 4:20 PM
For decades now, women navigating menopause have been buffeted by shifting research findings on the risks and possible benefits of hormone-replacement therapy. Now, a landmark clinical trial that followed more than 27,000 subjects for roughly 18 years has offered some conclusive evidence that neither the hype nor the grim warnings about hormone-replacement therapy were warranted.
In findings published Tuesday in the journal JAMA, women who were randomly assigned to take some form of hormone-replacement therapy for a median of six to seven years were no more, nor less, likely to die of any cause over the studys duration than were women who had been assigned to receive a placebo treatment.
The women who got synthetic estrogen and progesterone hormones to replace their naturally declining levels were no more (nor less) likely than those who got a placebo to die of stroke or heart failure. And they were neither more nor less likely to die of cardiovascular disease or cancer.
University of Pittsburgh Dr. Melissa McNeil, who wrote an editorial appearing alongside the new findings, called them both compelling and reassuring.
-snip-
By Melissa Healy
SEPTEMBER 12, 2017, 4:20 PM
For decades now, women navigating menopause have been buffeted by shifting research findings on the risks and possible benefits of hormone-replacement therapy. Now, a landmark clinical trial that followed more than 27,000 subjects for roughly 18 years has offered some conclusive evidence that neither the hype nor the grim warnings about hormone-replacement therapy were warranted.
In findings published Tuesday in the journal JAMA, women who were randomly assigned to take some form of hormone-replacement therapy for a median of six to seven years were no more, nor less, likely to die of any cause over the studys duration than were women who had been assigned to receive a placebo treatment.
The women who got synthetic estrogen and progesterone hormones to replace their naturally declining levels were no more (nor less) likely than those who got a placebo to die of stroke or heart failure. And they were neither more nor less likely to die of cardiovascular disease or cancer.
University of Pittsburgh Dr. Melissa McNeil, who wrote an editorial appearing alongside the new findings, called them both compelling and reassuring.
-snip-
Read more: http://www.latimes.com/science/sciencenow/la-sci-sn-hormone-therapy-safe-20170912-story.html
______________________________________________________________________
Related:
Findings: Menopausal Hormone Therapy and Long-term All-Cause and Cause-Specific Mortality (JAMA)
Editorial: Menopausal Hormone Therapy Understanding Long-term Risks and Benefits (JAMA)
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Up to 7 years of hormone therapy is safe for postmenopausal women, new data show (Original Post)
Eugene
Sep 2017
OP
It definitely is not safe if a woman has Leiden Factor V, a blood clotting condition.
blue neen
Sep 2017
#2
flamingdem
(39,313 posts)1. Thanks for posting this, it's a substantial study
and can put to rest some of the endless speculation and claims.
blue neen
(12,319 posts)2. It definitely is not safe if a woman has Leiden Factor V, a blood clotting condition.
Huh-uh.
Pregnant women with Leiden Factor V have to take Lovenox (blood thinner) shots. Estrogen and blood clotting disorders don't go together well.
MLAA
(17,288 posts)3. Thanks for posting.
still_one
(92,188 posts)4. Of course if someone has a breast cancer which is ER or PR positive, it would NOT be prudent to
supplement with Estrogen or Progesterone
Warpy
(111,255 posts)5. That is especially good for women in surgical menopause
and women in early perimenopause.
Laffy Kat
(16,377 posts)6. Uh oh. I might be reaching the limit.
They can have my HR pills when they pry them from my cold, dead fingers.
CountAllVotes
(20,868 posts)7. Reached that limit a couple of years ago
Now called "estrogen intolerant" ...
Very god damned unpleasant at best!
If lucky they'll give you some sort of cream that might help, MIGHT.
ms liberty
(8,573 posts)8. Bookmarking. Thanks for posting! n/t