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Fri Mar 8, 2019, 05:08 AM

New Ketamine-Related Drug for Depression- 'Spravato' Approved By FDA

Last edited Fri Mar 8, 2019, 04:44 PM - Edit history (1)

"New ketamine-related drug could be ‘watershed’ in treating depression." ‘Rapid acting’ esketamine was approved by the FDA to treat people who don’t respond to traditional psychiatric drugs. The Guardian, March 7, 2019.

Experts are cautiously optimistic a drug related to ketamine, recently approved by the US Food and Drug Administration, could be a “watershed” moment in the treatment of depression, and one of the first drugs to be a “rapid acting” medicine to treat the chronic disease. The new drug, called esketamine, will be sold under the brand name Spravato, and was approved to treat people with depression who don’t respond to traditional psychiatric drugs.

“For a long time, all our standard antidepressants have been ‘me too’ drugs,” said Dr Walter S Dunn, a professor of psychiatry at the University of California Los Angeles, and a member of the FDA advisory committee which recommended the drug be approved. “As much as the companies like to say our drug is better than the next, they were pretty much all the same,” said Dunn, referring to brand name drugs which work on similar pathways in the brain, such as selective serotonin re-uptake inhibitors like Prozac.

The newly-approved drug builds on years of research into ketamine as a treatment for major depression. Ketamine has long been seen as a safe drug for anesthesia, and has recently developed as a treatment for depression...


> MORE on Ketamine, psychedelic and other treatments:

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Reply New Ketamine-Related Drug for Depression- 'Spravato' Approved By FDA (Original post)
appalachiablue Mar 2019 OP
Sinistrous Mar 2019 #1
hlthe2b Mar 2019 #2

Response to appalachiablue (Original post)

Fri Mar 8, 2019, 05:35 AM

1. Approvals such as this make me wonder

who is going to get rich on this stuff.

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Response to Sinistrous (Reply #1)

Fri Mar 8, 2019, 06:26 AM

2. Especially since a generic form of ketamine is already legally used off label for this purpose

which has been found quite effective. Frankly, I would hope enough of those prescribing physician psychiatrists continue to use the generic form.

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