Human microbiome churns out thousands of tiny novel proteins
From http://med.stanford.edu/news/all-news/2019/08/human-microbiome-churns-out-thousands-of-tiny-novel-proteins.html
Human microbiome churns out thousands of tiny novel proteins
The bacteria in our gut make thousands of tiny, previously unidentified proteins that could shed light on human health and advance drug development, Stanford researchers have found.
AUG 8 2019
Ami Bhatt and her collaborators found that microbes in the human gut are making thousands of proteins so small that they've previously gone undetected.
Norbert von der Groeben
Your body is a wonderland. A wonderland teeming with trillions of bacteria, that is. But its not as horrifying as it might sound. In fact, theres mounting evidence that many aspects of our health are closely intertwined with the composition and hardiness of our microscopic compatriots, though exactly how is still mostly unclear.
Now, researchers at the Stanford University School of Medicine have discovered that these microbial hitchhikers collectively known as the human microbiome are churning out tens of thousands of proteins so small that theyve gone unnoticed in previous studies. The proteins belong to more than 4,000 new biological families predicted to be involved in, among other processes, the warfare waged among different bacterial strains as they vie for primacy in coveted biological niches, the cell-to-cell communication between microbes and their unwitting hosts, and the critical day-to-day housekeeping duties that keep the bacteria happy and healthy.
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Link:
Large-Scale Analyses of Human Microbiomes Reveal Thousands of Small, Novel Genes
https://doi.org/10.1016/j.cell.2019.07.016