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Has there ever been studies of certain diseases that look at a nominal rate from generation to generation, a nominal rate would be one adjusted for population growth.

Have such studies been done for various cancers, muscular problems, deadly allergies like nut allergies?

The reason that I ask this is some wondering that I did on the role of our modern diet, natural exercise rate changes (people used to do more manual work and got a workout from that), things like the air being full of low level electromagnetic waves today with modern communication, ect.