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Showing Original Post only (View all)Let's Be Accurate: The MMR Vaccine is Not Associated With Autism. But Neonatal Hep B in Males... [View all]
Here is the link to the study:
http://www.ncbi.nlm.nih.gov/pubmed/24814559
Here is the abstract:
There has been enormous debate regarding the possibility of a link between childhood vaccinations and the subsequent development of autism. This has in recent times become a major public health issue with vaccine preventable diseases increasing in the community due to the fear of a 'link' between vaccinations and autism. We performed a meta-analysis to summarise available evidence from case-control and cohort studies on this topic (MEDLINE, PubMed, EMBASE, Google Scholar up to April, 2014). Eligible studies assessed the relationship between vaccine administration and the subsequent development of autism or autism spectrum disorders (ASD). Two reviewers extracted data on study characteristics, methods, and outcomes. Disagreement was resolved by consensus with another author. Five cohort studies involving 1,256,407 children, and five case-control studies involving 9920 children were included in this analysis. The cohort data revealed no relationship between vaccination and autism (OR: 0.99; 95% CI: 0.92 to 1.06) or ASD (OR: 0.91; 95% CI: 0.68 to 1.20), or MMR (OR: 0.84; 95% CI: 0.70 to 1.01), or thimerosal (OR: 1.00; 95% CI: 0.77 to 1.31), or mercury (Hg) (OR: 1.00; 95% CI: 0.93 to 1.07). Similarly the case-control data found no evidence for increased risk of developing autism or ASD following MMR, Hg, or thimerosal exposure when grouped by condition (OR: 0.90, 95% CI: 0.83 to 0.98; p=0.02) or grouped by exposure type (OR: 0.85, 95% CI: 0.76 to 0.95; p=0.01). Findings of this meta-analysis suggest that vaccinations are not associated with the development of autism or autism spectrum disorder. Furthermore, the components of the vaccines (thimerosal or mercury) or multiple vaccines (MMR) are not associated with the development of autism or autism spectrum disorder.
Note that MMR was cleared. MMR was suspected because it is given at around 1 year of life. One year is when children typically walk and talk. If they do not walk and talk, the parents think back to the thing that happened right before they did not walk and talk---and they remember the MMR vaccine. This guilt by association obviously made no sense and it is a good thing that they have finally laid this myth to rest, since folks die of measles.
However, to say that no vaccine has been linked to autism is incorrect. There is one vaccine that is routinely given to newborn infants---infants whose brains and immune systems are so immature that simple viral infections can have devastating consequences. I am referring to the Hepatitis B vaccine. Why is this given to newborn infants? Because decades ago, scientists studied inner city hospitals where a lot of drug addicts gave birth and they discovered that it was cheaper to just immunize all the babies at birth than to test the mothers to see which were infected with Hep B and immunize their babies at birth. Meaning that you---you who are likely not an IV drug addict and who are likely immune to Hep B from the vaccine you received in school---will have a baby who will be given a vaccine shortly after its birth because that was what was best for drug addicts three decades ago.
What could go wrong with giving an extra, unnecessary vaccine to a newborn baby? The only study so far to find any statistical association between a vaccine and autism is one for male infants given the Hep B vaccine at birth.
http://www.ncbi.nlm.nih.gov/pubmed/21058170
Universal hepatitis B vaccination was recommended for U.S. newborns in 1991; however, safety findings are mixed. The association between hepatitis B vaccination of male neonates and parental report of autism diagnosis was determined. This cross-sectional study used weighted probability samples obtained from National Health Interview Survey 1997-2002 data sets. Vaccination status was determined from the vaccination record. Logistic regression was used to estimate the odds for autism diagnosis associated with neonatal hepatitis B vaccination among boys age 3-17 years, born before 1999, adjusted for race, maternal education, and two-parent household. Boys vaccinated as neonates had threefold greater odds for autism diagnosis compared to boys never vaccinated or vaccinated after the first month of life. Non-Hispanic white boys were 64% less likely to have autism diagnosis relative to nonwhite boys. Findings suggest that U.S. male neonates vaccinated with the hepatitis B vaccine prior to 1999 (from vaccination record) had a threefold higher risk for parental report of autism diagnosis compared to boys not vaccinated as neonates during that same time period. Nonwhite boys bore a greater risk.
Association does not prove causality. This study does not prove your child's autism was caused by a Hep B vaccine. It suggests that male children who get the vaccine at birth may be more likely to show signs of autism. I just did a Medline search and I can not find any more recent studies to either confirm or refute this study, meaning it is still up in the air. So, you get to decide what you do with the information. But, do not leave DU tonight telling all your friends "Great news. A study has cleared ALL vaccines."
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Let's Be Accurate: The MMR Vaccine is Not Associated With Autism. But Neonatal Hep B in Males... [View all]
McCamy Taylor
May 2014
OP
No argument here. Especially in China, India, Africa and places were chronic Hep B
McCamy Taylor
May 2014
#49
Actually, it is not hard to show that there is no association. If two things are
McCamy Taylor
May 2014
#7
Yes, there is a study that shows an association. It is the one linked above.
McCamy Taylor
May 2014
#25
You're not missing anything. This is just another study misrepresented by anti-vaxers.
HuckleB
May 2014
#28
No, it should be the job of those who would require all neonates to be given a vaccine
pnwmom
May 2014
#11
But they didn't find that correlation with MMR vaccine, which also changed significantly. n/t
lumberjack_jeff
May 2014
#34
actually it would get a pretty good chance of a lock as stupid ass CS bullshit.
Warren Stupidity
May 2014
#18
Nothing. It was nearly unanimous that more antivac idiocy wouldl be good for DU.
Warren Stupidity
May 2014
#64
That is true. That is why I am not Antivac. I am for informed Vaccination.
McCamy Taylor
May 2014
#36
My patients have to sign consent forms before they get vaccines. Big, long government consent forms.
McCamy Taylor
May 2014
#52
If it's not entirely due to Dx changes then there's an environmental factor.
lumberjack_jeff
May 2014
#57
If the rate is going up, and it's not entirely measurement error, then it's environmental.
lumberjack_jeff
May 2014
#62
Thanks. I tend to agree. However it can be very hard to get anyone interested in
McCamy Taylor
May 2014
#48
Agreed. With so many highly informed "experts" it should be no problem for them to
GoneFishin
May 2014
#76
You need to do an SOP alert. The OP is not rude or insulting, just whacko.
Warren Stupidity
May 2014
#46
yup you are right about this one Sid. Despite the horrifying effects of MMR antivac
Warren Stupidity
May 2014
#63
A study showing a statistical association is not cause for panic. It just means we need a
McCamy Taylor
May 2014
#21
I have a "rep"? This is the only study that has ever shown an association. Therefore it is the only
McCamy Taylor
May 2014
#30
Of course, studies about the safety of the full vaccination schedule show no issues.
HuckleB
May 2014
#44
And people here buy into it despite the disaster with the MMR antivac idiocy.
Warren Stupidity
May 2014
#66
One more thing to clarify,small premature babies should NOT get Hep B vaccine until one month of age
McCamy Taylor
May 2014
#70
The control group includes children born in 1980, 11 years before the vaccine was introduced
Major Nikon
May 2014
#73