Welcome to DU! The truly grassroots left-of-center political community where regular people, not algorithms, drive the discussions and set the standards. Join the community: Create a free account Support DU (and get rid of ads!): Become a Star Member Latest Breaking News General Discussion The DU Lounge All Forums Issue Forums Culture Forums Alliance Forums Region Forums Support Forums Help & Search

BumRushDaShow

(128,941 posts)
19. In general, there is pre-set criteria for efficacy of vaccines
Tue Mar 2, 2021, 10:33 AM
Mar 2021

and that is at least 50% effective. COVID-19 vaccine guidance (FDA PDF).

The FDA's cutoff for Covid-19 vaccine effectiveness is 50 percent. What does that mean?
No vaccine is 100 percent effective, but some work better than others.

Nov. 3, 2020, 4:58 AM EST
By Jacqueline Stenson

Over the summer, the Food and Drug Administration announced that in order for an experimental Covid-19 vaccine to get the green light, it would need to be safe and “prevent disease or decrease its severity in at least 50 percent of people who are vaccinated.”

In fact, no vaccine is 100 percent effective, but some work better than others. One of the most successful is the measles vaccine — two doses are 97 percent effective in preventing the disease, according to the Centers for Disease Control and Prevention. Still, 50 percent sounds like a far cry from 97 percent.

“I know that 50 percent does sound low but that is still some protection, and some protection is better than no protection,” said Dr. Jeff Kwong, professor of public health and family medicine and interim director of the Centre for Vaccine Preventable Diseases at the University of Toronto.

Based on the effectiveness threshold the FDA has set for a Covid-19 vaccine to be approved or granted emergency use authorization, it’s possible a vaccine becomes available that helps only half of people receiving it, while offering no benefit to the other half. It’s also possible that a vaccine could have different effects in different people – helping to prevent disease in some people while reducing the severity of Covid-19 in others.

https://www.nbcnews.com/health/health-news/fda-s-cutoff-covid-19-vaccine-effectiveness-50-percent-what-n1245506


Even with the annual flu vaccine(s), you are lucky to get 50 - 60% effectiveness if they can target the right ones that will end up in circulation here in the northern/western hemisphere.

Here is the general process for vaccine development - https://www.fda.gov/vaccines-blood-biologics/development-approval-process-cber/vaccine-development-101
Now that's unity! Auggie Mar 2021 #1
I'm sure they are gonna get a cut outta that! BumRushDaShow Mar 2021 #2
For sure ... Auggie Mar 2021 #4
Sweet! 2naSalit Mar 2021 #3
Fantastic news! NJCher Mar 2021 #5
I expect their vaccine production is done at different facitlies BumRushDaShow Mar 2021 #7
Great news! lkinwi Mar 2021 #6
This is great news. Arkansas Granny Mar 2021 #8
Grown ups are back Botany Mar 2021 #9
This is a BFD bucolic_frolic Mar 2021 #10
Post removed Post removed Mar 2021 #11
Janssen (J&J's company) is going through a trial with a double shot BumRushDaShow Mar 2021 #12
Until proven Bear Creek Mar 2021 #13
None of the vaccines are "approved" BumRushDaShow Mar 2021 #14
The others offer better protection Bear Creek Mar 2021 #16
In general, there is pre-set criteria for efficacy of vaccines BumRushDaShow Mar 2021 #19
Please stop spreading fear. The shot highly effective. tinrobot Mar 2021 #23
Post removed Post removed Mar 2021 #35
Again, please stop spreading misinformation. It does not help. tinrobot Mar 2021 #42
"It is not effective" TwilightZone Mar 2021 #63
Sorry - That's a badly misguided analysis FBaggins Mar 2021 #26
Actually it has Bear Creek Mar 2021 #37
No... it most certainly has not FBaggins Mar 2021 #48
That has nothing to do with the efficacy of the vaccine. TwilightZone Mar 2021 #65
Only J&J has even been tested against variants. Your comparison is unfounded. lagomorph777 Mar 2021 #30
Also tested in a different environment than Moderna/Pfizer Deminpenn Mar 2021 #47
Great, but too bad they aren't producing more of the more effective vaccines SheltieLover Mar 2021 #15
Exactly Bear Creek Mar 2021 #17
Exactly! SheltieLover Mar 2021 #18
You're not a scientist are you? BumRushDaShow Mar 2021 #21
No I'm not SheltieLover Mar 2021 #22
Hopefully this explains a little why this is going the way it is BumRushDaShow Mar 2021 #28
Post removed Post removed Mar 2021 #24
You're implying that this is the result of campaign contributions to Biden's campaign? ForgoTheConsequence Mar 2021 #54
Glad that got removed BumRushDaShow Mar 2021 #59
Same here. ForgoTheConsequence Mar 2021 #75
Remember that NORMAL vaccine devopment is a *multi-year* process BumRushDaShow Mar 2021 #20
Ty for sharing insights! SheltieLover Mar 2021 #25
Also see this (I think I stuck it in the wrong place) BumRushDaShow Mar 2021 #33
Ty again! SheltieLover Mar 2021 #44
YW BumRushDaShow Mar 2021 #49
No doubt! SheltieLover Mar 2021 #50
Unfair comparison. J&J's lower number includes variants. The others were tested pre-variant. lagomorph777 Mar 2021 #31
Sorry Bear Creek Mar 2021 #39
You're intentionally spreading misinformation. ForgoTheConsequence Mar 2021 #52
Profits. We live in a Global Corporate Oligarchy, never forget that simple fact. Tommymac Mar 2021 #40
I mentioned upthread that for big pharma BumRushDaShow Mar 2021 #45
See!! I knew they could do this! It's a win-win-win! lagomorph777 Mar 2021 #27
February 11th, Biden announced a contract extension with Pfizer and Moderna. House of Roberts Mar 2021 #29
Pfizer and Moderna's tests were before the variants. J&J's number includes South African and others lagomorph777 Mar 2021 #32
Can you show results of the J&J vaccine against the new variants House of Roberts Mar 2021 #36
No. The testing coincided with variant emergence. lagomorph777 Mar 2021 #38
Here is a link to the FDA/CBER's Vaccine Advisory Committee's meeting with them last Friday BumRushDaShow Mar 2021 #53
Please post a link to the studies otherwise this is just opinion. Tommymac Mar 2021 #41
Here you go lagomorph777 Mar 2021 #43
Here is the irony of this situation BumRushDaShow Mar 2021 #34
This is such good news for the entire world. THANK YOU for sharing h2ebits Mar 2021 #46
"Biden boosted production by invoking the National 'whatever it is called' Act" BumRushDaShow Mar 2021 #56
Yes and the orange dumbass was advised to do the same Yo_Mama_Been_Loggin Mar 2021 #58
They had Ford and GM make lots of ventilators BumRushDaShow Mar 2021 #60
I think they had to do the ventilator push Steelrolled Mar 2021 #67
When this was going on BumRushDaShow Mar 2021 #69
I was skeptical of the whole plan, having lots of experience with big companies, Steelrolled Mar 2021 #73
LOL--Whatever it takes to get my thoughts out h2ebits Mar 2021 #68
I know the feeling! BumRushDaShow Mar 2021 #70
The "wartime effort" was one of the things I was going to mention. BobTheSubgenius Mar 2021 #51
Excellent work Biden-Harris administration... Jon King Mar 2021 #55
This is what a real president does Donny boy Yo_Mama_Been_Loggin Mar 2021 #57
Good move. Similar to Sanofi and Pfizer. mwooldri Mar 2021 #61
I had seen where GSK/Sanofi were also going to try some of their other vaccine candidates BumRushDaShow Mar 2021 #66
This is HUGE! Bayard Mar 2021 #62
Of course Merck will do their own regular pharmaceutical stuff BumRushDaShow Mar 2021 #71
Thank you for fighting back against the lazy misinformation of some of the posters. SharonClark Mar 2021 #64
K and R oasis Mar 2021 #72
There are a lot of untrained and unlicensed amateur epidemiologists around these days. mpcamb Mar 2021 #74
Latest Discussions»Latest Breaking News»Biden to announce 'histor...»Reply #19