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In reply to the discussion: Biden to announce 'historic partnership': Merck will help make Johnson & Johnson coronavirus vaccine [View all]BumRushDaShow
(128,941 posts)19. In general, there is pre-set criteria for efficacy of vaccines
and that is at least 50% effective. COVID-19 vaccine guidance (FDA PDF).
The FDA's cutoff for Covid-19 vaccine effectiveness is 50 percent. What does that mean?
No vaccine is 100 percent effective, but some work better than others.
Nov. 3, 2020, 4:58 AM EST
By Jacqueline Stenson
Over the summer, the Food and Drug Administration announced that in order for an experimental Covid-19 vaccine to get the green light, it would need to be safe and prevent disease or decrease its severity in at least 50 percent of people who are vaccinated.
In fact, no vaccine is 100 percent effective, but some work better than others. One of the most successful is the measles vaccine two doses are 97 percent effective in preventing the disease, according to the Centers for Disease Control and Prevention. Still, 50 percent sounds like a far cry from 97 percent.
I know that 50 percent does sound low but that is still some protection, and some protection is better than no protection, said Dr. Jeff Kwong, professor of public health and family medicine and interim director of the Centre for Vaccine Preventable Diseases at the University of Toronto.
Based on the effectiveness threshold the FDA has set for a Covid-19 vaccine to be approved or granted emergency use authorization, its possible a vaccine becomes available that helps only half of people receiving it, while offering no benefit to the other half. Its also possible that a vaccine could have different effects in different people helping to prevent disease in some people while reducing the severity of Covid-19 in others.
https://www.nbcnews.com/health/health-news/fda-s-cutoff-covid-19-vaccine-effectiveness-50-percent-what-n1245506
No vaccine is 100 percent effective, but some work better than others.
Nov. 3, 2020, 4:58 AM EST
By Jacqueline Stenson
Over the summer, the Food and Drug Administration announced that in order for an experimental Covid-19 vaccine to get the green light, it would need to be safe and prevent disease or decrease its severity in at least 50 percent of people who are vaccinated.
In fact, no vaccine is 100 percent effective, but some work better than others. One of the most successful is the measles vaccine two doses are 97 percent effective in preventing the disease, according to the Centers for Disease Control and Prevention. Still, 50 percent sounds like a far cry from 97 percent.
I know that 50 percent does sound low but that is still some protection, and some protection is better than no protection, said Dr. Jeff Kwong, professor of public health and family medicine and interim director of the Centre for Vaccine Preventable Diseases at the University of Toronto.
Based on the effectiveness threshold the FDA has set for a Covid-19 vaccine to be approved or granted emergency use authorization, its possible a vaccine becomes available that helps only half of people receiving it, while offering no benefit to the other half. Its also possible that a vaccine could have different effects in different people helping to prevent disease in some people while reducing the severity of Covid-19 in others.
https://www.nbcnews.com/health/health-news/fda-s-cutoff-covid-19-vaccine-effectiveness-50-percent-what-n1245506
Even with the annual flu vaccine(s), you are lucky to get 50 - 60% effectiveness if they can target the right ones that will end up in circulation here in the northern/western hemisphere.
Here is the general process for vaccine development - https://www.fda.gov/vaccines-blood-biologics/development-approval-process-cber/vaccine-development-101
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Biden to announce 'historic partnership': Merck will help make Johnson & Johnson coronavirus vaccine [View all]
BumRushDaShow
Mar 2021
OP
Only J&J has even been tested against variants. Your comparison is unfounded.
lagomorph777
Mar 2021
#30
Great, but too bad they aren't producing more of the more effective vaccines
SheltieLover
Mar 2021
#15
You're implying that this is the result of campaign contributions to Biden's campaign?
ForgoTheConsequence
Mar 2021
#54
Unfair comparison. J&J's lower number includes variants. The others were tested pre-variant.
lagomorph777
Mar 2021
#31
Profits. We live in a Global Corporate Oligarchy, never forget that simple fact.
Tommymac
Mar 2021
#40
February 11th, Biden announced a contract extension with Pfizer and Moderna.
House of Roberts
Mar 2021
#29
Pfizer and Moderna's tests were before the variants. J&J's number includes South African and others
lagomorph777
Mar 2021
#32
Here is a link to the FDA/CBER's Vaccine Advisory Committee's meeting with them last Friday
BumRushDaShow
Mar 2021
#53
"Biden boosted production by invoking the National 'whatever it is called' Act"
BumRushDaShow
Mar 2021
#56
I was skeptical of the whole plan, having lots of experience with big companies,
Steelrolled
Mar 2021
#73
I had seen where GSK/Sanofi were also going to try some of their other vaccine candidates
BumRushDaShow
Mar 2021
#66
Thank you for fighting back against the lazy misinformation of some of the posters.
SharonClark
Mar 2021
#64