Health

Red Pest

(288 posts)

14. Very interesting paper but...

Tue Jun 11, 2019, 05:13 PM

Jun 2019

1. These observations must be confirmed by others and extended.

2. They have yet to do any trials in animals to show that the inhibitors of PARPs will selectively block deposition in the ECM and not in bones.

3. Even if it works in mice or rats, it may not work in humans. There are all sorts of treatments that work in model animals like mice or rats, but fail to work or are unsafe in humans.

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Cause of Hardening of the Arteries- And Potential Treatment- Identified (H) [View all] appalachiablue Jun 2019 OP

To the Greatest Page with you. n/t area51 Jun 2019 #1

Treatment identified is good news pandr32 Jun 2019 #2

'Affordable,' yes! appalachiablue Jun 2019 #3

K&Fuckin' R Guy Whitey Corngood Jun 2019 #4

If the treatment doesn't lead to osteoporosis, it will be a huge breakthrough. DFW Jun 2019 #5

Hopefully they've factored that into reasearch, esp. since appalachiablue Jun 2019 #7

I really hope so, too. It's not much help if it's only a trade-off. DFW Jun 2019 #8

See #9 re 'bone' appalachiablue Jun 2019 #13

From the OP eggplant Jun 2019 #9

TY, that's impt. to know, and good news. appalachiablue Jun 2019 #12

K&R Great post, thanks. alwaysinasnit Jun 2019 #6

Science Marches On Progressive2020 Jun 2019 #10

No, no, no, no Farmer-Rick Jun 2019 #11

Very interesting paper but... Red Pest Jun 2019 #14

K&R UTUSN Jun 2019 #15