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NNadir

(33,516 posts)
4. Yes, I stand corrected. Heaviest is appropriate.
Mon Dec 24, 2018, 12:59 AM
Dec 2018

I was relying on my memory, and I'm an old man and can be excused on grounds of senility.

I know that 17O has a spin of 5/2, but I can't recall ever reading about NMR experiments involving it, although I'm sure it's been done.

I'm so old that when I was a kid, people had to enrich 13C to get an NMR signal from it, and now of course, with high field instruments it's rather routine with native isotopes, no enrichment necessary.

Of course 13C is more than 1%.

I imagine that a 17O experiment would involve a lot of acquisition time and a very high field instrument, but I don't know.

Amazing things are happening in NMR if I understand correctly. I went to a lecture by a Pfizer guy not too long ago where he seemed to have a pulse sequence to suppress solvent peaks so that he could follow, in real time, reaction progress by NMR.

I'm so old that I didn't think things like that were possible, but they are.

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