The Germans had plenty of uranium (we made good use of it after capturing it) but they had no more heavy water nor any other critical materials necessary, nor any way to make use of the energy produced. Even if it had worked it would have been only a first experimental step like CP-1, and they had no resources to continue research. I once saw it stated that the only reason they were bothering was to salvage the reputation of German science once the war was well and truly lost.
If they had been able to pursue carbon as a moderator, or if they had not been denied isotope separation by the fact that the single means they had the resources to try didn't work with uranium hexaflouride, and most importantly if Hitler hadn't gotten the whole country bogged down in Russia in the winter with Operation Barbarossa, then there might have been a non-laughable chance of the Germans getting some kind of effective nuclear technology. As it was, just a useless waste of resources they would have gotten more benefit from directed toward some more practical element of the war -- much as with the V-weapons and jet aircraft which were never effective enough to justify their high costs.