Most of the Middle East had been much more secular and peaceful.
The US armed the fundies to fight the commies. Most of the crazies were concentrated in US supported Saudi Arabia. The US very much helped spread the ideology. With the constant US brutalization of the entire region, that set up an environment where conservative religious views can much more easily spread.
The US also arms and supports the most brutal leaders, including supporting Saddam in his unprovoked war against Iran. The US helped in the creation of Iraq's chemical weapons program and supplied the intelligence on how to employ the chemical weapons against Iran, the very same Iran that the US had overthrown their secular leader and installed the brutal Shah.
The US helps in the ethnic cleansing of Palestine and Israel's brutalization of all of Israel's neighbors.
Under Barack Obama, the U.S. is currently bombing Afghanistan, Iraq, Pakistan, Yemen, Somalia, and Libya. According to some reports (see here and here), we can add Iran to this ever-expanding list. [Update: An Informed Comment reader named Shannon pointed out that in fact the United States bombed Iran in 1988 during Operating Praying Mantis, an act that cannot be justified according to the International Court of Justice.]
Thanks to American arms and funding, our stalwart ally Israel has bombed every single one of its neighbors, including Palestine, Lebanon, Syria, Jordan, and Egypt. Israel has also bombed Tunisia and Iraq (how many times can Americans and Israelis bomb this country?).
The total number of Muslim countries that America and Israel have bombed comes to fourteen: Afghanistan, Iraq, Pakistan, Yemen, Somalia, Libya, Iran, Sudan, Palestine, Lebanon, Syria, Jordan, Egypt, and Tunisia.
This is something approaching genocide.